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Blood B, T, CD4+ and CD8+ lymphocytes in female Wistar rats

Standard

Blood B, T, CD4+ and CD8+ lymphocytes in female Wistar rats. / Franch, A; Castellote, C; Pelegrí, C; Tolosa, E; Castell, M.

in: ANN HEMATOL, Jahrgang 67, Nr. 3, 01.09.1993, S. 115-8.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Franch, A, Castellote, C, Pelegrí, C, Tolosa, E & Castell, M 1993, 'Blood B, T, CD4+ and CD8+ lymphocytes in female Wistar rats', ANN HEMATOL, Jg. 67, Nr. 3, S. 115-8.

APA

Franch, A., Castellote, C., Pelegrí, C., Tolosa, E., & Castell, M. (1993). Blood B, T, CD4+ and CD8+ lymphocytes in female Wistar rats. ANN HEMATOL, 67(3), 115-8.

Vancouver

Franch A, Castellote C, Pelegrí C, Tolosa E, Castell M. Blood B, T, CD4+ and CD8+ lymphocytes in female Wistar rats. ANN HEMATOL. 1993 Sep 1;67(3):115-8.

Bibtex

@article{9417a2cc324643e1adafaa197b9181b0,
title = "Blood B, T, CD4+ and CD8+ lymphocytes in female Wistar rats",
abstract = "We have established reference values of peripheral blood lymphocyte subsets in healthy female Wistar rats under highly standardized conditions. Using monoclonal antibodies and flow cytometry, T lymphocytes (OX19+), B lymphocytes (OX6+ and anti-Ig+), T-helper/inducer (W3/25+), and T-suppressor/cytotoxic subsets (OX8+) were determined, from week 11 to week 21 after birth. The mean percentages of T and B lymphocytes with respect to total lymphocytes were 78.5% and 18%, respectively; the mean percentages of T-helper/inducer and T-suppressor/cytotoxic cells in relation to T lymphocytes were 59% and 25%, respectively (n = 48). No difference in total leukocyte count, differential leukocyte analysis, or lymphocyte subsets was observed during the 10 weeks the rats were studied under standard housing conditions. Therefore, the period considered seems the most appropriate in which to carry out experiments that could involve lymphocyte subset disturbances.",
keywords = "Animals, Antigens, CD8, B-Lymphocyte Subsets, CD4-Positive T-Lymphocytes, Cell Separation, Female, Flow Cytometry, Leukocyte Count, Lymphocyte Subsets, Rats, Rats, Wistar, Reference Values, T-Lymphocyte Subsets",
author = "A Franch and C Castellote and C Pelegr{\'i} and E Tolosa and M Castell",
year = "1993",
month = sep,
day = "1",
language = "English",
volume = "67",
pages = "115--8",
journal = "ANN HEMATOL",
issn = "0939-5555",
publisher = "Springer",
number = "3",

}

RIS

TY - JOUR

T1 - Blood B, T, CD4+ and CD8+ lymphocytes in female Wistar rats

AU - Franch, A

AU - Castellote, C

AU - Pelegrí, C

AU - Tolosa, E

AU - Castell, M

PY - 1993/9/1

Y1 - 1993/9/1

N2 - We have established reference values of peripheral blood lymphocyte subsets in healthy female Wistar rats under highly standardized conditions. Using monoclonal antibodies and flow cytometry, T lymphocytes (OX19+), B lymphocytes (OX6+ and anti-Ig+), T-helper/inducer (W3/25+), and T-suppressor/cytotoxic subsets (OX8+) were determined, from week 11 to week 21 after birth. The mean percentages of T and B lymphocytes with respect to total lymphocytes were 78.5% and 18%, respectively; the mean percentages of T-helper/inducer and T-suppressor/cytotoxic cells in relation to T lymphocytes were 59% and 25%, respectively (n = 48). No difference in total leukocyte count, differential leukocyte analysis, or lymphocyte subsets was observed during the 10 weeks the rats were studied under standard housing conditions. Therefore, the period considered seems the most appropriate in which to carry out experiments that could involve lymphocyte subset disturbances.

AB - We have established reference values of peripheral blood lymphocyte subsets in healthy female Wistar rats under highly standardized conditions. Using monoclonal antibodies and flow cytometry, T lymphocytes (OX19+), B lymphocytes (OX6+ and anti-Ig+), T-helper/inducer (W3/25+), and T-suppressor/cytotoxic subsets (OX8+) were determined, from week 11 to week 21 after birth. The mean percentages of T and B lymphocytes with respect to total lymphocytes were 78.5% and 18%, respectively; the mean percentages of T-helper/inducer and T-suppressor/cytotoxic cells in relation to T lymphocytes were 59% and 25%, respectively (n = 48). No difference in total leukocyte count, differential leukocyte analysis, or lymphocyte subsets was observed during the 10 weeks the rats were studied under standard housing conditions. Therefore, the period considered seems the most appropriate in which to carry out experiments that could involve lymphocyte subset disturbances.

KW - Animals

KW - Antigens, CD8

KW - B-Lymphocyte Subsets

KW - CD4-Positive T-Lymphocytes

KW - Cell Separation

KW - Female

KW - Flow Cytometry

KW - Leukocyte Count

KW - Lymphocyte Subsets

KW - Rats

KW - Rats, Wistar

KW - Reference Values

KW - T-Lymphocyte Subsets

M3 - SCORING: Journal article

C2 - 8104040

VL - 67

SP - 115

EP - 118

JO - ANN HEMATOL

JF - ANN HEMATOL

SN - 0939-5555

IS - 3

ER -