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Biologically Active Metabolites from the Marine Sediment-Derived Fungus Aspergillus flocculosus

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Biologically Active Metabolites from the Marine Sediment-Derived Fungus Aspergillus flocculosus. / Yurchenko, Anton N; Trinh, Phan Thi Hoai; Girich Ivanets, Elena V; Smetanina, Olga F; Rasin, Anton B; Popov, Roman S; Dyshlovoy, Sergey A; von Amsberg, Gunhild; Menchinskaya, Ekaterina S; Thanh Van, Tran Thi; Afiyatullov, Shamil Sh.

in: MAR DRUGS, Jahrgang 17, Nr. 10, 11.10.2019.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Yurchenko, AN, Trinh, PTH, Girich Ivanets, EV, Smetanina, OF, Rasin, AB, Popov, RS, Dyshlovoy, SA, von Amsberg, G, Menchinskaya, ES, Thanh Van, TT & Afiyatullov, SS 2019, 'Biologically Active Metabolites from the Marine Sediment-Derived Fungus Aspergillus flocculosus', MAR DRUGS, Jg. 17, Nr. 10. https://doi.org/10.3390/md17100579

APA

Yurchenko, A. N., Trinh, P. T. H., Girich Ivanets, E. V., Smetanina, O. F., Rasin, A. B., Popov, R. S., Dyshlovoy, S. A., von Amsberg, G., Menchinskaya, E. S., Thanh Van, T. T., & Afiyatullov, S. S. (2019). Biologically Active Metabolites from the Marine Sediment-Derived Fungus Aspergillus flocculosus. MAR DRUGS, 17(10). https://doi.org/10.3390/md17100579

Vancouver

Yurchenko AN, Trinh PTH, Girich Ivanets EV, Smetanina OF, Rasin AB, Popov RS et al. Biologically Active Metabolites from the Marine Sediment-Derived Fungus Aspergillus flocculosus. MAR DRUGS. 2019 Okt 11;17(10). https://doi.org/10.3390/md17100579

Bibtex

@article{a37cc511e4cf4da6b4c30f16fea081ee,
title = "Biologically Active Metabolites from the Marine Sediment-Derived Fungus Aspergillus flocculosus",
abstract = "Four new compounds were isolated from the Vietnamese marine sediment-derived fungus Aspergillus flocculosus, one aspyrone-related polyketide aspilactonol G (2), one meroterpenoid 12-epi-aspertetranone D (4), two drimane derivatives (7,9), together with five known metabolites (1,3,5,6,8,10). The structures of compounds 1-10 were established by NMR and MS techniques. The absolute stereoconfigurations of compounds 1 and 2 were determined by a modified Mosher's method. The absolute configurations of compounds 4 and 7 were established by a combination of analysis of ROESY data and coupling constants as well as biogenetic considerations. Compounds 7 and 8 exhibited cytotoxic activity toward human prostate cancer 22Rv1, human breast cancer MCF-7, and murine neuroblastoma Neuro-2a cells.",
author = "Yurchenko, {Anton N} and Trinh, {Phan Thi Hoai} and {Girich Ivanets}, {Elena V} and Smetanina, {Olga F} and Rasin, {Anton B} and Popov, {Roman S} and Dyshlovoy, {Sergey A} and {von Amsberg}, Gunhild and Menchinskaya, {Ekaterina S} and {Thanh Van}, {Tran Thi} and Afiyatullov, {Shamil Sh}",
year = "2019",
month = oct,
day = "11",
doi = "10.3390/md17100579",
language = "English",
volume = "17",
journal = "MAR DRUGS",
issn = "1660-3397",
publisher = "MDPI AG",
number = "10",

}

RIS

TY - JOUR

T1 - Biologically Active Metabolites from the Marine Sediment-Derived Fungus Aspergillus flocculosus

AU - Yurchenko, Anton N

AU - Trinh, Phan Thi Hoai

AU - Girich Ivanets, Elena V

AU - Smetanina, Olga F

AU - Rasin, Anton B

AU - Popov, Roman S

AU - Dyshlovoy, Sergey A

AU - von Amsberg, Gunhild

AU - Menchinskaya, Ekaterina S

AU - Thanh Van, Tran Thi

AU - Afiyatullov, Shamil Sh

PY - 2019/10/11

Y1 - 2019/10/11

N2 - Four new compounds were isolated from the Vietnamese marine sediment-derived fungus Aspergillus flocculosus, one aspyrone-related polyketide aspilactonol G (2), one meroterpenoid 12-epi-aspertetranone D (4), two drimane derivatives (7,9), together with five known metabolites (1,3,5,6,8,10). The structures of compounds 1-10 were established by NMR and MS techniques. The absolute stereoconfigurations of compounds 1 and 2 were determined by a modified Mosher's method. The absolute configurations of compounds 4 and 7 were established by a combination of analysis of ROESY data and coupling constants as well as biogenetic considerations. Compounds 7 and 8 exhibited cytotoxic activity toward human prostate cancer 22Rv1, human breast cancer MCF-7, and murine neuroblastoma Neuro-2a cells.

AB - Four new compounds were isolated from the Vietnamese marine sediment-derived fungus Aspergillus flocculosus, one aspyrone-related polyketide aspilactonol G (2), one meroterpenoid 12-epi-aspertetranone D (4), two drimane derivatives (7,9), together with five known metabolites (1,3,5,6,8,10). The structures of compounds 1-10 were established by NMR and MS techniques. The absolute stereoconfigurations of compounds 1 and 2 were determined by a modified Mosher's method. The absolute configurations of compounds 4 and 7 were established by a combination of analysis of ROESY data and coupling constants as well as biogenetic considerations. Compounds 7 and 8 exhibited cytotoxic activity toward human prostate cancer 22Rv1, human breast cancer MCF-7, and murine neuroblastoma Neuro-2a cells.

U2 - 10.3390/md17100579

DO - 10.3390/md17100579

M3 - SCORING: Journal article

C2 - 31614563

VL - 17

JO - MAR DRUGS

JF - MAR DRUGS

SN - 1660-3397

IS - 10

ER -