Biofilm formation in medical device-related infection.

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Biofilm formation in medical device-related infection. / Mack, D; Rohde, Holger; Harris, L G; Davies, A P; Horstkotte, M A; Knobloch, J K-M.

in: INT J ARTIF ORGANS, Jahrgang 29, Nr. 4, 4, 2006, S. 343-359.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{b2799a7a26a94965bd8f3225c5a745a7,
title = "Biofilm formation in medical device-related infection.",
abstract = "Medical device-associated infections, most frequently caused by coagulase-negative staphylococci, especially Staphylococcus epidermidis, are of increasing importance in modern medicine. Regularly, antimicrobial therapy fails without removal of the implanted device. The most important factor in the pathogenesis of medical device-associated staphylococcal infections is the formation of adherent, multilayered bacterial biofilms. There is urgent need for an increased understanding of the functional factors involved in biofilm formation, the regulation of their expression, and the interaction of those potential virulence factors in device related infection with the host. Significant progress has been made in recent years which may ultimately lead to new rational approaches for better preventive, therapeutic, and diagnostic measures.",
author = "D Mack and Holger Rohde and Harris, {L G} and Davies, {A P} and Horstkotte, {M A} and Knobloch, {J K-M}",
year = "2006",
doi = "10.1177/039139880602900404",
language = "Deutsch",
volume = "29",
pages = "343--359",
journal = "INT J ARTIF ORGANS",
issn = "0391-3988",
publisher = "Wichtig Publishing",
number = "4",

}

RIS

TY - JOUR

T1 - Biofilm formation in medical device-related infection.

AU - Mack, D

AU - Rohde, Holger

AU - Harris, L G

AU - Davies, A P

AU - Horstkotte, M A

AU - Knobloch, J K-M

PY - 2006

Y1 - 2006

N2 - Medical device-associated infections, most frequently caused by coagulase-negative staphylococci, especially Staphylococcus epidermidis, are of increasing importance in modern medicine. Regularly, antimicrobial therapy fails without removal of the implanted device. The most important factor in the pathogenesis of medical device-associated staphylococcal infections is the formation of adherent, multilayered bacterial biofilms. There is urgent need for an increased understanding of the functional factors involved in biofilm formation, the regulation of their expression, and the interaction of those potential virulence factors in device related infection with the host. Significant progress has been made in recent years which may ultimately lead to new rational approaches for better preventive, therapeutic, and diagnostic measures.

AB - Medical device-associated infections, most frequently caused by coagulase-negative staphylococci, especially Staphylococcus epidermidis, are of increasing importance in modern medicine. Regularly, antimicrobial therapy fails without removal of the implanted device. The most important factor in the pathogenesis of medical device-associated staphylococcal infections is the formation of adherent, multilayered bacterial biofilms. There is urgent need for an increased understanding of the functional factors involved in biofilm formation, the regulation of their expression, and the interaction of those potential virulence factors in device related infection with the host. Significant progress has been made in recent years which may ultimately lead to new rational approaches for better preventive, therapeutic, and diagnostic measures.

U2 - 10.1177/039139880602900404

DO - 10.1177/039139880602900404

M3 - SCORING: Zeitschriftenaufsatz

VL - 29

SP - 343

EP - 359

JO - INT J ARTIF ORGANS

JF - INT J ARTIF ORGANS

SN - 0391-3988

IS - 4

M1 - 4

ER -