Betel quid-associated oral lesions and oral Candida species in a female Cambodian cohort
Standard
Betel quid-associated oral lesions and oral Candida species in a female Cambodian cohort. / Reichart, P A; Schmidtberg, W; Samaranayake, L P; Scheifele, C.
in: J ORAL PATHOL MED, Jahrgang 31, Nr. 8, 01.09.2002, S. 468-72.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Betel quid-associated oral lesions and oral Candida species in a female Cambodian cohort
AU - Reichart, P A
AU - Schmidtberg, W
AU - Samaranayake, L P
AU - Scheifele, C
PY - 2002/9/1
Y1 - 2002/9/1
N2 - BACKGROUND: Betel quid chewing (BQC) is still prevalent among elderly Cambodian women and is associated with a wide variety of oral mucosal lesions. BQC has also been associated with a reduced rate of dental caries and changes in the oral microbiological flora.METHODS: Since no studies were available on the impact of BQC on the oral carriage of Candida species, in this study oral swabs (Fungiquick, Hain Diagnostika, Germany) were taken from the tongue and palate of 48 Cambodian women with BQC habit (study group) and 13 control subjects without BQC habit (control group) to determine the spectrum of Candida species in these two groups. In addition, we investigated lesions of the oral mucosa likely to be associated with BQC habit in both study and control groups.RESULTS: The median duration of BQC was 10 years (range 10 months-30 years). The following oral lesions were found in the study group: betel chewer's mucosa (85.4%), oral leukoplakia (8.3%), leukoedema (37.5%) and oral lichen planus (4.2%). Oral candidiasis was seen neither in BQ-chewers nor in controls. Candida spp. were found in 70.8% of the cases (controls 69.2%). Whilst C. albicans was isolated from 27.1% of the study cohort, C. tropicalis was the second most common isolate. One control case was colonised by C. dubliniensis--the first report of this organism from a Cambodian population. There was no significant difference in the candidal carriage rate or the Candida species isolated between the study and the control group.CONCLUSIONS: Mycological findings from the present study do not indicate that BQC has a significant effect on oral colonisation by Candida species.
AB - BACKGROUND: Betel quid chewing (BQC) is still prevalent among elderly Cambodian women and is associated with a wide variety of oral mucosal lesions. BQC has also been associated with a reduced rate of dental caries and changes in the oral microbiological flora.METHODS: Since no studies were available on the impact of BQC on the oral carriage of Candida species, in this study oral swabs (Fungiquick, Hain Diagnostika, Germany) were taken from the tongue and palate of 48 Cambodian women with BQC habit (study group) and 13 control subjects without BQC habit (control group) to determine the spectrum of Candida species in these two groups. In addition, we investigated lesions of the oral mucosa likely to be associated with BQC habit in both study and control groups.RESULTS: The median duration of BQC was 10 years (range 10 months-30 years). The following oral lesions were found in the study group: betel chewer's mucosa (85.4%), oral leukoplakia (8.3%), leukoedema (37.5%) and oral lichen planus (4.2%). Oral candidiasis was seen neither in BQ-chewers nor in controls. Candida spp. were found in 70.8% of the cases (controls 69.2%). Whilst C. albicans was isolated from 27.1% of the study cohort, C. tropicalis was the second most common isolate. One control case was colonised by C. dubliniensis--the first report of this organism from a Cambodian population. There was no significant difference in the candidal carriage rate or the Candida species isolated between the study and the control group.CONCLUSIONS: Mycological findings from the present study do not indicate that BQC has a significant effect on oral colonisation by Candida species.
KW - Adult
KW - Aged
KW - Aged, 80 and over
KW - Areca/adverse effects
KW - Cambodia
KW - Candida/classification
KW - Candida albicans/isolation & purification
KW - Candida glabrata/isolation & purification
KW - Candida tropicalis/isolation & purification
KW - Chi-Square Distribution
KW - Cohort Studies
KW - Colony Count, Microbial
KW - Female
KW - Humans
KW - Leukoedema, Oral/etiology
KW - Leukoplakia, Oral/etiology
KW - Lichen Planus, Oral/etiology
KW - Middle Aged
KW - Mouth Diseases/etiology
KW - Mouth Mucosa/microbiology
KW - Palate/microbiology
KW - Reagent Strips
KW - Smoking/adverse effects
KW - Statistics, Nonparametric
KW - Time Factors
KW - Tongue/microbiology
U2 - 10.1034/j.1600-0714.2002.00009.x
DO - 10.1034/j.1600-0714.2002.00009.x
M3 - SCORING: Journal article
C2 - 12220354
VL - 31
SP - 468
EP - 472
JO - J ORAL PATHOL MED
JF - J ORAL PATHOL MED
SN - 0904-2512
IS - 8
ER -