beta-Endorphin immunoreactive materials in human plasma determined by a multiple radioimmunoassay system.

Klaus Wiedemann; H Teschemacher

beta-Endorphin immunoreactive materials in human plasma determined by a multiple radioimmunoassay system.

Standard

beta-Endorphin immunoreactive materials in human plasma determined by a multiple radioimmunoassay system. / Wiedemann, Klaus; Teschemacher, H.

in: LIFE SCI, Jahrgang 33, Nr. 1, 1, 1983, S. 89-92.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Wiedemann, K & Teschemacher, H 1983, 'beta-Endorphin immunoreactive materials in human plasma determined by a multiple radioimmunoassay system.', LIFE SCI, Jg. 33, Nr. 1, 1, S. 89-92. <http://www.ncbi.nlm.nih.gov/pubmed/6319930?dopt=Citation>

APA

Wiedemann, K., & Teschemacher, H. (1983). beta-Endorphin immunoreactive materials in human plasma determined by a multiple radioimmunoassay system. LIFE SCI, 33(1), 89-92. [1]. http://www.ncbi.nlm.nih.gov/pubmed/6319930?dopt=Citation

Vancouver

Wiedemann K, Teschemacher H. beta-Endorphin immunoreactive materials in human plasma determined by a multiple radioimmunoassay system. LIFE SCI. 1983;33(1):89-92. 1.

Bibtex

@article{fd075d3d1996409aba5e96fc28777a16,

title = "beta-Endorphin immunoreactive materials in human plasma determined by a multiple radioimmunoassay system.",

abstract = "Extracts of plasma obtained from adult humans before and immediately after physical stress were subjected to high pressure liquid chromatography (HPLC); extracts or HPLC fractions, resp., were analysed for the presence of human beta-endorphin (beta H-endorphin) or fragments thereof by several radioimmunoassays using antibodies directed against the C-terminus and two {"}middle{"} regions of beta H-endorphin. Using an antibody ({"}Don Antonio{"}) apparently directed against a beta H-endorphin fragment including positions 17 to 22 or somewhat adjacent regions, concentrations of beta H-endorphin immunoreactivity were found to be in the well-known range under normal conditions and to increase after physical stress. However, only a minor portion of this material proved to be identical with beta H-endorphin, whereas the major portion behaved like a smaller fragment thereof. In addition, high amounts of an immunoreactive material obviously containing a C-terminal sequence of beta H-endorphin were found, indicating the presence of an immunologically relevant beta H-endorphin fragment in the plasma.",

author = "Klaus Wiedemann and H Teschemacher",

year = "1983",

language = "Deutsch",

volume = "33",

pages = "89--92",

journal = "LIFE SCI",

issn = "0024-3205",

publisher = "Elsevier Inc.",

number = "1",

}

RIS

TY - JOUR

T1 - beta-Endorphin immunoreactive materials in human plasma determined by a multiple radioimmunoassay system.

AU - Wiedemann, Klaus

AU - Teschemacher, H

PY - 1983

Y1 - 1983

N2 - Extracts of plasma obtained from adult humans before and immediately after physical stress were subjected to high pressure liquid chromatography (HPLC); extracts or HPLC fractions, resp., were analysed for the presence of human beta-endorphin (beta H-endorphin) or fragments thereof by several radioimmunoassays using antibodies directed against the C-terminus and two "middle" regions of beta H-endorphin. Using an antibody ("Don Antonio") apparently directed against a beta H-endorphin fragment including positions 17 to 22 or somewhat adjacent regions, concentrations of beta H-endorphin immunoreactivity were found to be in the well-known range under normal conditions and to increase after physical stress. However, only a minor portion of this material proved to be identical with beta H-endorphin, whereas the major portion behaved like a smaller fragment thereof. In addition, high amounts of an immunoreactive material obviously containing a C-terminal sequence of beta H-endorphin were found, indicating the presence of an immunologically relevant beta H-endorphin fragment in the plasma.

AB - Extracts of plasma obtained from adult humans before and immediately after physical stress were subjected to high pressure liquid chromatography (HPLC); extracts or HPLC fractions, resp., were analysed for the presence of human beta-endorphin (beta H-endorphin) or fragments thereof by several radioimmunoassays using antibodies directed against the C-terminus and two "middle" regions of beta H-endorphin. Using an antibody ("Don Antonio") apparently directed against a beta H-endorphin fragment including positions 17 to 22 or somewhat adjacent regions, concentrations of beta H-endorphin immunoreactivity were found to be in the well-known range under normal conditions and to increase after physical stress. However, only a minor portion of this material proved to be identical with beta H-endorphin, whereas the major portion behaved like a smaller fragment thereof. In addition, high amounts of an immunoreactive material obviously containing a C-terminal sequence of beta H-endorphin were found, indicating the presence of an immunologically relevant beta H-endorphin fragment in the plasma.

M3 - SCORING: Zeitschriftenaufsatz

VL - 33

SP - 89

EP - 92

JO - LIFE SCI

JF - LIFE SCI

SN - 0024-3205

IS - 1

M1 - 1

ER -