Atrial fibrillation in women: treatment
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Atrial fibrillation in women: treatment. / Ko, Darae; Rahman, Faisal; Martins, Maria A P; Hylek, Elaine M; Ellinor, Patrick T; Schnabel, Renate B; Benjamin, Emelia J; Christophersen, Ingrid E.
in: NAT REV CARDIOL, Jahrgang 14, Nr. 2, 02.2017, S. 113-124.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung
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TY - JOUR
T1 - Atrial fibrillation in women: treatment
AU - Ko, Darae
AU - Rahman, Faisal
AU - Martins, Maria A P
AU - Hylek, Elaine M
AU - Ellinor, Patrick T
AU - Schnabel, Renate B
AU - Benjamin, Emelia J
AU - Christophersen, Ingrid E
PY - 2017/2
Y1 - 2017/2
N2 - Sex-specific differences in the epidemiology, pathophysiology, presentation, prognosis, and treatment of atrial fibrillation (AF) are increasingly recognized. Women with AF generally experience worse symptoms, poorer quality of life, and have higher risk of stroke and death than men with AF. Effective treatment of the arrhythmia in women is critical to reduce the rate of adverse events. We review the current evidence on sex-specific differences in the utilization and outcomes of treatments for AF, including rate-control and rhythm-control strategies, and stroke-prevention therapy. In addition, we provide a critical evaluation of potential disparities and biases in health-care use that might be associated with differences in the outcomes between women and men. We underscore current knowledge gaps that need to be addressed in future studies to improve the management of AF in women. In particular, we suggest several strategies to produce high-quality evidence from randomized clinical trials for women with AF.
AB - Sex-specific differences in the epidemiology, pathophysiology, presentation, prognosis, and treatment of atrial fibrillation (AF) are increasingly recognized. Women with AF generally experience worse symptoms, poorer quality of life, and have higher risk of stroke and death than men with AF. Effective treatment of the arrhythmia in women is critical to reduce the rate of adverse events. We review the current evidence on sex-specific differences in the utilization and outcomes of treatments for AF, including rate-control and rhythm-control strategies, and stroke-prevention therapy. In addition, we provide a critical evaluation of potential disparities and biases in health-care use that might be associated with differences in the outcomes between women and men. We underscore current knowledge gaps that need to be addressed in future studies to improve the management of AF in women. In particular, we suggest several strategies to produce high-quality evidence from randomized clinical trials for women with AF.
KW - Atrial Fibrillation/epidemiology
KW - Female
KW - Humans
KW - Patient Care Management/methods
KW - Prognosis
KW - Quality of Life
KW - Sex Factors
U2 - 10.1038/nrcardio.2016.171
DO - 10.1038/nrcardio.2016.171
M3 - SCORING: Review article
C2 - 27786235
VL - 14
SP - 113
EP - 124
JO - NAT REV CARDIOL
JF - NAT REV CARDIOL
SN - 1759-5002
IS - 2
ER -