INTRODUCTION: For patients attending the emergency room (ER) valid diagnostic criteria which identify patients at risk for an adverse outcome are needed. We investigated the predictive value of asymmetric dimethylarginine (ADMA) in unselected patients attending an internal medicine ER regarding outcome of the patients and duration of stay in the hospital. PATIENTS AND METHODS: Patients (n=417) attending the ER were classified according to their primary diagnosis. Routine laboratory tests were performed and ADMA was determined. Patients were followed for a primary endpoint of in hospital death and complicated outcome. RESULTS: ADMA levels were highest in patients with a cancer-related diagnosis (0.76 (0.63-0.93) micromol/L) and in patients with a cardiovascular diagnosis (0.69 (0.60-0.80) micromol/L; p
