Asymmetric and symmetric dimethylarginine and risk of secondary cardiovascular disease events and mortality in patients with stable coronary heart disease: the KAROLA follow-up study.

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Asymmetric and symmetric dimethylarginine and risk of secondary cardiovascular disease events and mortality in patients with stable coronary heart disease: the KAROLA follow-up study. / Siegerink, Bob; Maas, Renke; Vossen, Carla Y; Schwedhelm, Edzard; Koenig, Wolfgang; Böger, Rainer; Rothenbacher, Dietrich; Brenner, Hermann; Breitling, Lutz P.

in: CLIN RES CARDIOL, Jahrgang 102, Nr. 3, 3, 2013, S. 193-202.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{233b80948ffd49da9983a08807058de1,
title = "Asymmetric and symmetric dimethylarginine and risk of secondary cardiovascular disease events and mortality in patients with stable coronary heart disease: the KAROLA follow-up study.",
abstract = "Asymmetric dimethylarginine (ADMA) is an endogenous nitric oxide synthase inhibitor, which has been associated with total and cardiovascular mortality in various clinical settings. Studies on its structural isomer, symmetric dimethylarginine (SDMA), are scarce. This study aimed to determine the associations of both ADMA and SDMA levels with secondary cardiovascular disease events and all-cause mortality in patients with stable coronary heart disease (CHD).",
keywords = "Humans, Male, Aged, Female, Middle Aged, Risk Factors, Multivariate Analysis, Prospective Studies, Predictive Value of Tests, Prognosis, Risk Assessment, Follow-Up Studies, Time Factors, Proportional Hazards Models, Cause of Death, Recurrence, Kaplan-Meier Estimate, Chromatography, Liquid, Tandem Mass Spectrometry, Germany/epidemiology, Arginine/*analogs & derivatives/blood, Biological Markers/blood, Coronary Disease/*blood/diagnosis/*mortality, Humans, Male, Aged, Female, Middle Aged, Risk Factors, Multivariate Analysis, Prospective Studies, Predictive Value of Tests, Prognosis, Risk Assessment, Follow-Up Studies, Time Factors, Proportional Hazards Models, Cause of Death, Recurrence, Kaplan-Meier Estimate, Chromatography, Liquid, Tandem Mass Spectrometry, Germany/epidemiology, Arginine/*analogs & derivatives/blood, Biological Markers/blood, Coronary Disease/*blood/diagnosis/*mortality",
author = "Bob Siegerink and Renke Maas and Vossen, {Carla Y} and Edzard Schwedhelm and Wolfgang Koenig and Rainer B{\"o}ger and Dietrich Rothenbacher and Hermann Brenner and Breitling, {Lutz P}",
year = "2013",
language = "English",
volume = "102",
pages = "193--202",
journal = "CLIN RES CARDIOL",
issn = "1861-0684",
publisher = "D. Steinkopff-Verlag",
number = "3",

}

RIS

TY - JOUR

T1 - Asymmetric and symmetric dimethylarginine and risk of secondary cardiovascular disease events and mortality in patients with stable coronary heart disease: the KAROLA follow-up study.

AU - Siegerink, Bob

AU - Maas, Renke

AU - Vossen, Carla Y

AU - Schwedhelm, Edzard

AU - Koenig, Wolfgang

AU - Böger, Rainer

AU - Rothenbacher, Dietrich

AU - Brenner, Hermann

AU - Breitling, Lutz P

PY - 2013

Y1 - 2013

N2 - Asymmetric dimethylarginine (ADMA) is an endogenous nitric oxide synthase inhibitor, which has been associated with total and cardiovascular mortality in various clinical settings. Studies on its structural isomer, symmetric dimethylarginine (SDMA), are scarce. This study aimed to determine the associations of both ADMA and SDMA levels with secondary cardiovascular disease events and all-cause mortality in patients with stable coronary heart disease (CHD).

AB - Asymmetric dimethylarginine (ADMA) is an endogenous nitric oxide synthase inhibitor, which has been associated with total and cardiovascular mortality in various clinical settings. Studies on its structural isomer, symmetric dimethylarginine (SDMA), are scarce. This study aimed to determine the associations of both ADMA and SDMA levels with secondary cardiovascular disease events and all-cause mortality in patients with stable coronary heart disease (CHD).

KW - Humans

KW - Male

KW - Aged

KW - Female

KW - Middle Aged

KW - Risk Factors

KW - Multivariate Analysis

KW - Prospective Studies

KW - Predictive Value of Tests

KW - Prognosis

KW - Risk Assessment

KW - Follow-Up Studies

KW - Time Factors

KW - Proportional Hazards Models

KW - Cause of Death

KW - Recurrence

KW - Kaplan-Meier Estimate

KW - Chromatography, Liquid

KW - Tandem Mass Spectrometry

KW - Germany/epidemiology

KW - Arginine/analogs & derivatives/blood

KW - Biological Markers/blood

KW - Coronary Disease/blood/diagnosis/mortality

KW - Humans

KW - Male

KW - Aged

KW - Female

KW - Middle Aged

KW - Risk Factors

KW - Multivariate Analysis

KW - Prospective Studies

KW - Predictive Value of Tests

KW - Prognosis

KW - Risk Assessment

KW - Follow-Up Studies

KW - Time Factors

KW - Proportional Hazards Models

KW - Cause of Death

KW - Recurrence

KW - Kaplan-Meier Estimate

KW - Chromatography, Liquid

KW - Tandem Mass Spectrometry

KW - Germany/epidemiology

KW - Arginine/analogs & derivatives/blood

KW - Biological Markers/blood

KW - Coronary Disease/blood/diagnosis/mortality

M3 - SCORING: Journal article

VL - 102

SP - 193

EP - 202

JO - CLIN RES CARDIOL

JF - CLIN RES CARDIOL

SN - 1861-0684

IS - 3

M1 - 3

ER -