Association between c135G/A genotype and RET proto-oncogene germline mutations and phenotype of Hirschsprung's disease.
Beteiligte Einrichtungen
Abstract
Several genes, including the major susceptibility gene RET, have roles in development of Hirschsprung's disease. Results of genetic-linkage analysis of patients with familial disease with both long-segment and short-segment phenotypes have shown close linkage with the RET locus. We aimed to investigate whether both RET mutations and polymorphisms contribute to phenotype of Hirschsprung's disease.
Bibliografische Daten
| Originalsprache | Deutsch |
|---|---|
| Aufsatznummer | 9313 |
| ISSN | 0140-6736 |
| Status | Veröffentlicht - 2002 |
| pubmed | 11955539 |
|---|
