Association between a serotonin transporter gene variant and hopelessness among men in the heart and soul study.

  • Kirsten Neudoerffer Kangelaris
  • Eric Vittinghoff
  • Christian Otte
  • Beeya Na
  • Andrew D Auerbach
  • Mary A Whooley

Abstract

Hopelessness is associated with mortality in patients with cardiac disease even after accounting for severity of depression. We sought to determine whether a polymorphism in the promoter region of the serotonin transporter gene (5-HTTLPR) is associated with increased hopelessness, and whether this effect is modified by sex, age, antidepressant use or depression in patients with coronary heart disease.

Bibliografische Daten

OriginalspracheDeutsch
Aufsatznummer10
ISSN0884-8734
StatusVeröffentlicht - 2010
pubmed 20509052