Assessment of the enhancement in predictive accuracy provided by systematic biopsy in predicting outcome for clinically localized prostate cancer.
Standard
Assessment of the enhancement in predictive accuracy provided by systematic biopsy in predicting outcome for clinically localized prostate cancer. / Graefen, Markus; Ohori, Makoto; Karakiewicz, Pierre I; Cagiannos, Ilias; Hammerer, Peter G; Haese, Alexander; Erbersdobler, Andreas; Henke, Rolf-Peter; Huland, Hartwig; Wheeler, Thomas M; Slawin, Kevin; Scardino, Peter T; Kattan, Michael W.
in: J UROLOGY, Jahrgang 171, Nr. 1, 1, 2004, S. 200-203.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Assessment of the enhancement in predictive accuracy provided by systematic biopsy in predicting outcome for clinically localized prostate cancer.
AU - Graefen, Markus
AU - Ohori, Makoto
AU - Karakiewicz, Pierre I
AU - Cagiannos, Ilias
AU - Hammerer, Peter G
AU - Haese, Alexander
AU - Erbersdobler, Andreas
AU - Henke, Rolf-Peter
AU - Huland, Hartwig
AU - Wheeler, Thomas M
AU - Slawin, Kevin
AU - Scardino, Peter T
AU - Kattan, Michael W
PY - 2004
Y1 - 2004
N2 - PURPOSE: Current localized prostate cancer treatment outcome nomograms rely on prostate specific antigen (PSA), tumor stage and grade. We investigated whether the addition of prostate biopsy features may enhance the accuracy of a nomogram predicting recurrence after radical prostatectomy (RP). MATERIALS AND METHODS: Clinical data from 1,152 patients who underwent RP were used and included PSA, clinical stage, biopsy Gleason grade and systematic biopsy information that quantified the amount of cancer and high grade cancer. Predictive accuracy for freedom from recurrence after RP was assessed with and without tumor quantification in the biopsy by the area under the receiver operating characteristics curve (AUC). RESULTS: Percentage and number of cores with cancer, and percentage and number of cores with high grade cancer were predictors of outcome when added to models that included PSA, Gleason grade and clinical stage (all p
AB - PURPOSE: Current localized prostate cancer treatment outcome nomograms rely on prostate specific antigen (PSA), tumor stage and grade. We investigated whether the addition of prostate biopsy features may enhance the accuracy of a nomogram predicting recurrence after radical prostatectomy (RP). MATERIALS AND METHODS: Clinical data from 1,152 patients who underwent RP were used and included PSA, clinical stage, biopsy Gleason grade and systematic biopsy information that quantified the amount of cancer and high grade cancer. Predictive accuracy for freedom from recurrence after RP was assessed with and without tumor quantification in the biopsy by the area under the receiver operating characteristics curve (AUC). RESULTS: Percentage and number of cores with cancer, and percentage and number of cores with high grade cancer were predictors of outcome when added to models that included PSA, Gleason grade and clinical stage (all p
M3 - SCORING: Zeitschriftenaufsatz
VL - 171
SP - 200
EP - 203
JO - J UROLOGY
JF - J UROLOGY
SN - 0022-5347
IS - 1
M1 - 1
ER -