Ascending aortic aneurysm and aortic valve dysfunction in bicuspid aortic valve disease.

Muhammet Ali Aydin; Nikolaus Desai; Alexander Bernhardt; Hendrik Treede; Christian Detter; Sara Sheikhzadeh; Meike Rybczynski; Mathias Hillebrand; Viktoria Lorenzen; Kai Mortensen; Peter N Robinson; Jürgen Berger; Hermann Reichenspurner; Thomas Meinertz; Stephan Willems; Yskert Von Kodolitsch

doi:10.1016/j.ijcard.2011.07.018

Ascending aortic aneurysm and aortic valve dysfunction in bicuspid aortic valve disease.

Standard

Ascending aortic aneurysm and aortic valve dysfunction in bicuspid aortic valve disease. / Aydin, Muhammet Ali; Desai, Nikolaus; Bernhardt, Alexander ; Treede, Hendrik ; Detter, Christian; Sheikhzadeh, Sara; Rybczynski, Meike; Hillebrand, Mathias; Lorenzen, Viktoria; Mortensen, Kai; Robinson, Peter N; Berger, Jürgen; Reichenspurner, Hermann; Meinertz, Thomas; Willems, Stephan; Von Kodolitsch, Yskert.

in: INT J CARDIOL, Jahrgang 164, Nr. 3, 15.04.2013, S. 301-305.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Aydin, MA, Desai, N, Bernhardt, A , Treede, H , Detter, C, Sheikhzadeh, S, Rybczynski, M, Hillebrand, M, Lorenzen, V, Mortensen, K, Robinson, PN, Berger, J, Reichenspurner, H, Meinertz, T, Willems, S & Von Kodolitsch, Y 2013, 'Ascending aortic aneurysm and aortic valve dysfunction in bicuspid aortic valve disease.', INT J CARDIOL, Jg. 164, Nr. 3, S. 301-305. https://doi.org/10.1016/j.ijcard.2011.07.018

APA

Aydin, M. A., Desai, N., Bernhardt, A., Treede, H., Detter, C., Sheikhzadeh, S., Rybczynski, M., Hillebrand, M., Lorenzen, V., Mortensen, K., Robinson, P. N., Berger, J., Reichenspurner, H., Meinertz, T., Willems, S., & Von Kodolitsch, Y. (2013). Ascending aortic aneurysm and aortic valve dysfunction in bicuspid aortic valve disease. INT J CARDIOL, 164(3), 301-305. https://doi.org/10.1016/j.ijcard.2011.07.018

Vancouver

Aydin MA, Desai N, Bernhardt A , Treede H , Detter C, Sheikhzadeh S et al. Ascending aortic aneurysm and aortic valve dysfunction in bicuspid aortic valve disease. INT J CARDIOL. 2013 Apr 15;164(3):301-305. https://doi.org/10.1016/j.ijcard.2011.07.018

Bibtex

@article{86ec943d54fc4195b3942df216090863,

title = "Ascending aortic aneurysm and aortic valve dysfunction in bicuspid aortic valve disease.",

abstract = "BACKGROUND: The relationship of aortic valve dysfunction and ascending aortic aneurysm is unclear in adults with bicuspid aortic valve disease.METHODS: We retrospectively studied 134 consecutive out-patients (98 men, 36 women aged 43 ± 18 years) with bicuspid aortic valve disease. To investigate the relationship of ascending aortic aneurysm and aortic valve dysfunction we exclusively considered severe pathologies that required treatment by surgical or percutaneous intervention.RESULTS: Of 134 patients, 39 had aortic valve dysfunction without concomitant ascending aortic aneurysm which had been treated previously with isolated valve surgery or percutaneous valvuloplasty comprising 25 patients with aortic stenosis (19%) and 14 patients with aortic regurgitation (10%). Conversely, 26 patients had ascending aortic aneurysm which had been treated previously with aortic surgery (19%). Of these, ascending aortic aneurysm was associated with severe aortic stenosis in 13 patients and with severe aortic regurgitation in 7 patients, whereas aneurysm was unrelated to severe aortic valve dysfunction in the remaining 6 patients including 2 without any degree of aortic valve dysfunction. The maximal aortic diameters were similar at the time of aortic surgery irrespective of presence of severe aortic valve dysfunction (P=.527). Other characteristics of patients with ascending aortic aneurysm were also similar irrespective of presence or type of aortic valve dysfunction.CONCLUSION: The majority of patients with bicuspid aortic valve disease exhibit ascending aortic aneurysm in conjunction with severe aortic valve dysfunction. However, in our study 6 of 134 (5%) of persons with bicuspid aortic valve disease developed ascending aortic aneurysm without aortic valve dysfunction.",

author = "Aydin, {Muhammet Ali} and Nikolaus Desai and Alexander Bernhardt and Hendrik Treede and Christian Detter and Sara Sheikhzadeh and Meike Rybczynski and Mathias Hillebrand and Viktoria Lorenzen and Kai Mortensen and Robinson, {Peter N} and J{\"u}rgen Berger and Hermann Reichenspurner and Thomas Meinertz and Stephan Willems and {Von Kodolitsch}, Yskert",

year = "2013",

month = apr,

day = "15",

doi = "10.1016/j.ijcard.2011.07.018",

language = "English",

volume = "164",

pages = "301--305",

journal = "INT J CARDIOL",

issn = "0167-5273",

publisher = "Elsevier Ireland Ltd",

number = "3",

}

RIS

TY - JOUR

T1 - Ascending aortic aneurysm and aortic valve dysfunction in bicuspid aortic valve disease.

AU - Aydin, Muhammet Ali

AU - Desai, Nikolaus

AU - Bernhardt, Alexander

AU - Treede, Hendrik

AU - Detter, Christian

AU - Sheikhzadeh, Sara

AU - Rybczynski, Meike

AU - Hillebrand, Mathias

AU - Lorenzen, Viktoria

AU - Mortensen, Kai

AU - Robinson, Peter N

AU - Berger, Jürgen

AU - Reichenspurner, Hermann

AU - Meinertz, Thomas

AU - Willems, Stephan

AU - Von Kodolitsch, Yskert

PY - 2013/4/15

Y1 - 2013/4/15

N2 - BACKGROUND: The relationship of aortic valve dysfunction and ascending aortic aneurysm is unclear in adults with bicuspid aortic valve disease.METHODS: We retrospectively studied 134 consecutive out-patients (98 men, 36 women aged 43 ± 18 years) with bicuspid aortic valve disease. To investigate the relationship of ascending aortic aneurysm and aortic valve dysfunction we exclusively considered severe pathologies that required treatment by surgical or percutaneous intervention.RESULTS: Of 134 patients, 39 had aortic valve dysfunction without concomitant ascending aortic aneurysm which had been treated previously with isolated valve surgery or percutaneous valvuloplasty comprising 25 patients with aortic stenosis (19%) and 14 patients with aortic regurgitation (10%). Conversely, 26 patients had ascending aortic aneurysm which had been treated previously with aortic surgery (19%). Of these, ascending aortic aneurysm was associated with severe aortic stenosis in 13 patients and with severe aortic regurgitation in 7 patients, whereas aneurysm was unrelated to severe aortic valve dysfunction in the remaining 6 patients including 2 without any degree of aortic valve dysfunction. The maximal aortic diameters were similar at the time of aortic surgery irrespective of presence of severe aortic valve dysfunction (P=.527). Other characteristics of patients with ascending aortic aneurysm were also similar irrespective of presence or type of aortic valve dysfunction.CONCLUSION: The majority of patients with bicuspid aortic valve disease exhibit ascending aortic aneurysm in conjunction with severe aortic valve dysfunction. However, in our study 6 of 134 (5%) of persons with bicuspid aortic valve disease developed ascending aortic aneurysm without aortic valve dysfunction.

AB - BACKGROUND: The relationship of aortic valve dysfunction and ascending aortic aneurysm is unclear in adults with bicuspid aortic valve disease.METHODS: We retrospectively studied 134 consecutive out-patients (98 men, 36 women aged 43 ± 18 years) with bicuspid aortic valve disease. To investigate the relationship of ascending aortic aneurysm and aortic valve dysfunction we exclusively considered severe pathologies that required treatment by surgical or percutaneous intervention.RESULTS: Of 134 patients, 39 had aortic valve dysfunction without concomitant ascending aortic aneurysm which had been treated previously with isolated valve surgery or percutaneous valvuloplasty comprising 25 patients with aortic stenosis (19%) and 14 patients with aortic regurgitation (10%). Conversely, 26 patients had ascending aortic aneurysm which had been treated previously with aortic surgery (19%). Of these, ascending aortic aneurysm was associated with severe aortic stenosis in 13 patients and with severe aortic regurgitation in 7 patients, whereas aneurysm was unrelated to severe aortic valve dysfunction in the remaining 6 patients including 2 without any degree of aortic valve dysfunction. The maximal aortic diameters were similar at the time of aortic surgery irrespective of presence of severe aortic valve dysfunction (P=.527). Other characteristics of patients with ascending aortic aneurysm were also similar irrespective of presence or type of aortic valve dysfunction.CONCLUSION: The majority of patients with bicuspid aortic valve disease exhibit ascending aortic aneurysm in conjunction with severe aortic valve dysfunction. However, in our study 6 of 134 (5%) of persons with bicuspid aortic valve disease developed ascending aortic aneurysm without aortic valve dysfunction.

U2 - 10.1016/j.ijcard.2011.07.018

DO - 10.1016/j.ijcard.2011.07.018

M3 - SCORING: Journal article

C2 - 21802748

VL - 164

SP - 301

EP - 305

JO - INT J CARDIOL

JF - INT J CARDIOL

SN - 0167-5273

IS - 3

ER -