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Aortic arch repair: let it beat!

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Aortic arch repair: let it beat! / Rüffer, A; Klopsch, C; Münch, F; Gottschalk, U; Mir, T S; Weil, J; Reichenspurner, H C; Cesnjevar, R A.

in: THORAC CARDIOV SURG, Jahrgang 60, Nr. 3, 04.2012, S. 189-194.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Rüffer, A, Klopsch, C, Münch, F, Gottschalk, U, Mir, TS, Weil, J, Reichenspurner, HC & Cesnjevar, RA 2012, 'Aortic arch repair: let it beat!', THORAC CARDIOV SURG, Jg. 60, Nr. 3, S. 189-194. https://doi.org/10.1055/s-0030-1271042

APA

Rüffer, A., Klopsch, C., Münch, F., Gottschalk, U., Mir, T. S., Weil, J., Reichenspurner, H. C., & Cesnjevar, R. A. (2012). Aortic arch repair: let it beat! THORAC CARDIOV SURG, 60(3), 189-194. https://doi.org/10.1055/s-0030-1271042

Vancouver

Rüffer A, Klopsch C, Münch F, Gottschalk U, Mir TS, Weil J et al. Aortic arch repair: let it beat! THORAC CARDIOV SURG. 2012 Apr;60(3):189-194. https://doi.org/10.1055/s-0030-1271042

Bibtex

@article{907ff38e4e814587b6017cad406a7e84,
title = "Aortic arch repair: let it beat!",
abstract = "Objective aortic arch repair (AAR) on the beating heart may reduce cross-clamping times and offer improved postoperative cardiac function.Methods A single-center review of all patients (n = 24) who underwent surgical AAR during biventricular repair between 01/2006 and 01/2008 was done. All patients were operated on under cardiopulmonary bypass (CPB) with antegrade cerebral perfusion (ACP). During AAR, 13 patients (group 1) received cardioplegic arrest, and were compared to 11 patients (group 2) who underwent a beating-heart modification with selective myocardial perfusion. Seventeen patients had additional intracardiac lesions and underwent simultaneous correction during the procedure.Results Durations of CPB, AAR and ACP did not differ statistically between groups. Cardioplegic arrest time was significantly lower in group 1 (34 ± 13 vs. 76 ± 11 min, p = 0.02) and resulted in a subsequent reduction of myocardial ischemic damage as borne out by lower postoperative levels of troponin T and CK-MB (2.5 ± 0.7 vs. 7.1 ± 1.4 ng/mL, p = 0.02; 68.7 ± 11.5 vs. 149.1 ± 27.2 U/l, p = 0.03). We observed an enhanced patient recovery with shorter inotropic and ventilatory support times (p < 0.05).Conclusion Pediatric aortic arch correction on a CPB beating heart with selective myocardial perfusion is technically feasible and safe. The reduction of the myocardial ischemic time is effective and results in less myocardial damage.",
keywords = "Aorta, Thoracic/abnormalities, Biomarkers/blood, Cardiopulmonary Bypass, Cardiotonic Agents/therapeutic use, Cerebrovascular Circulation, Coronary Circulation, Creatine Kinase, MB Form/blood, Female, Germany, Heart Arrest, Induced/adverse effects, Heart Defects, Congenital/diagnostic imaging, Hospital Mortality, Humans, Infant, Infant, Newborn, Male, Myocardial Ischemia/blood, Perfusion/methods, Recovery of Function, Respiration, Artificial, Retrospective Studies, Time Factors, Treatment Outcome, Troponin T/blood, Ultrasonography, Vascular Surgical Procedures/adverse effects",
author = "A R{\"u}ffer and C Klopsch and F M{\"u}nch and U Gottschalk and Mir, {T S} and J Weil and Reichenspurner, {H C} and Cesnjevar, {R A}",
note = "Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.",
year = "2012",
month = apr,
doi = "10.1055/s-0030-1271042",
language = "English",
volume = "60",
pages = "189--194",
journal = "THORAC CARDIOV SURG",
issn = "0171-6425",
publisher = "Georg Thieme Verlag KG",
number = "3",

}

RIS

TY - JOUR

T1 - Aortic arch repair: let it beat!

AU - Rüffer, A

AU - Klopsch, C

AU - Münch, F

AU - Gottschalk, U

AU - Mir, T S

AU - Weil, J

AU - Reichenspurner, H C

AU - Cesnjevar, R A

N1 - Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

PY - 2012/4

Y1 - 2012/4

N2 - Objective aortic arch repair (AAR) on the beating heart may reduce cross-clamping times and offer improved postoperative cardiac function.Methods A single-center review of all patients (n = 24) who underwent surgical AAR during biventricular repair between 01/2006 and 01/2008 was done. All patients were operated on under cardiopulmonary bypass (CPB) with antegrade cerebral perfusion (ACP). During AAR, 13 patients (group 1) received cardioplegic arrest, and were compared to 11 patients (group 2) who underwent a beating-heart modification with selective myocardial perfusion. Seventeen patients had additional intracardiac lesions and underwent simultaneous correction during the procedure.Results Durations of CPB, AAR and ACP did not differ statistically between groups. Cardioplegic arrest time was significantly lower in group 1 (34 ± 13 vs. 76 ± 11 min, p = 0.02) and resulted in a subsequent reduction of myocardial ischemic damage as borne out by lower postoperative levels of troponin T and CK-MB (2.5 ± 0.7 vs. 7.1 ± 1.4 ng/mL, p = 0.02; 68.7 ± 11.5 vs. 149.1 ± 27.2 U/l, p = 0.03). We observed an enhanced patient recovery with shorter inotropic and ventilatory support times (p < 0.05).Conclusion Pediatric aortic arch correction on a CPB beating heart with selective myocardial perfusion is technically feasible and safe. The reduction of the myocardial ischemic time is effective and results in less myocardial damage.

AB - Objective aortic arch repair (AAR) on the beating heart may reduce cross-clamping times and offer improved postoperative cardiac function.Methods A single-center review of all patients (n = 24) who underwent surgical AAR during biventricular repair between 01/2006 and 01/2008 was done. All patients were operated on under cardiopulmonary bypass (CPB) with antegrade cerebral perfusion (ACP). During AAR, 13 patients (group 1) received cardioplegic arrest, and were compared to 11 patients (group 2) who underwent a beating-heart modification with selective myocardial perfusion. Seventeen patients had additional intracardiac lesions and underwent simultaneous correction during the procedure.Results Durations of CPB, AAR and ACP did not differ statistically between groups. Cardioplegic arrest time was significantly lower in group 1 (34 ± 13 vs. 76 ± 11 min, p = 0.02) and resulted in a subsequent reduction of myocardial ischemic damage as borne out by lower postoperative levels of troponin T and CK-MB (2.5 ± 0.7 vs. 7.1 ± 1.4 ng/mL, p = 0.02; 68.7 ± 11.5 vs. 149.1 ± 27.2 U/l, p = 0.03). We observed an enhanced patient recovery with shorter inotropic and ventilatory support times (p < 0.05).Conclusion Pediatric aortic arch correction on a CPB beating heart with selective myocardial perfusion is technically feasible and safe. The reduction of the myocardial ischemic time is effective and results in less myocardial damage.

KW - Aorta, Thoracic/abnormalities

KW - Biomarkers/blood

KW - Cardiopulmonary Bypass

KW - Cardiotonic Agents/therapeutic use

KW - Cerebrovascular Circulation

KW - Coronary Circulation

KW - Creatine Kinase, MB Form/blood

KW - Female

KW - Germany

KW - Heart Arrest, Induced/adverse effects

KW - Heart Defects, Congenital/diagnostic imaging

KW - Hospital Mortality

KW - Humans

KW - Infant

KW - Infant, Newborn

KW - Male

KW - Myocardial Ischemia/blood

KW - Perfusion/methods

KW - Recovery of Function

KW - Respiration, Artificial

KW - Retrospective Studies

KW - Time Factors

KW - Treatment Outcome

KW - Troponin T/blood

KW - Ultrasonography

KW - Vascular Surgical Procedures/adverse effects

U2 - 10.1055/s-0030-1271042

DO - 10.1055/s-0030-1271042

M3 - SCORING: Journal article

C2 - 21528469

VL - 60

SP - 189

EP - 194

JO - THORAC CARDIOV SURG

JF - THORAC CARDIOV SURG

SN - 0171-6425

IS - 3

ER -