Anwendung und Nutzen kardialer Biomarker in der Praxis
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Anwendung und Nutzen kardialer Biomarker in der Praxis. / Brunner, F. J.; Blankenberg, S.
in: KARDIOLOGE, Jahrgang 7, Nr. 5, 10.2013, S. 377-386.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung
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TY - JOUR
T1 - Anwendung und Nutzen kardialer Biomarker in der Praxis
AU - Brunner, F. J.
AU - Blankenberg, S.
PY - 2013/10
Y1 - 2013/10
N2 - For the application of biological markers in the clinical routine a benefit in the diagnosis of acute and chronic cardiac diseases is well known. Currently, the use of cardiac troponins to identify patients with acute non-ST-segment elevation myocardial infarction is well established. Furthermore, the quantification of natriuretic peptides can be used for the exclusion of acute and chronic heart failure. Additionally, the possible implementation of biological markers in the individual risk prediction is under investigation. Further studies need to be carried out to show whether the use of different biological markers could lead to a better treatment in a primary or secondary preventive setting. Due to the development of new assays detection of cardiac troponin levels at a very low concentration is possible. In the future the detection of these low troponin concentrations could become a diagnostic benefit for cardiovascular risk prediction.
AB - For the application of biological markers in the clinical routine a benefit in the diagnosis of acute and chronic cardiac diseases is well known. Currently, the use of cardiac troponins to identify patients with acute non-ST-segment elevation myocardial infarction is well established. Furthermore, the quantification of natriuretic peptides can be used for the exclusion of acute and chronic heart failure. Additionally, the possible implementation of biological markers in the individual risk prediction is under investigation. Further studies need to be carried out to show whether the use of different biological markers could lead to a better treatment in a primary or secondary preventive setting. Due to the development of new assays detection of cardiac troponin levels at a very low concentration is possible. In the future the detection of these low troponin concentrations could become a diagnostic benefit for cardiovascular risk prediction.
KW - Cardiac troponin
KW - Heart failure
KW - Myocardial infarction
KW - Natriuretic peptide
KW - Prevention
UR - http://www.scopus.com/inward/record.url?scp=84892947228&partnerID=8YFLogxK
U2 - 10.1007/s12181-013-0500-9
DO - 10.1007/s12181-013-0500-9
M3 - SCORING: Zeitschriftenaufsatz
AN - SCOPUS:84892947228
VL - 7
SP - 377
EP - 386
JO - KARDIOLOGE
JF - KARDIOLOGE
SN - 1864-9718
IS - 5
ER -