Anti-proliferative activity of the quassinoid NBT-272 in childhood medulloblastoma cells.

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Anti-proliferative activity of the quassinoid NBT-272 in childhood medulloblastoma cells. / von Bueren, André; André, O; Shalaby, Tarek; Rajtarova, Julia; Stearns, Duncan; Eberhart, Charles G; Helson, Lawrence; Arcaro, Alexandre; Grotzer, Michael A.

in: BMC CANCER, Jahrgang 7, 2007, S. 19.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

Harvard

von Bueren, A, André, O, Shalaby, T, Rajtarova, J, Stearns, D, Eberhart, CG, Helson, L, Arcaro, A & Grotzer, MA 2007, 'Anti-proliferative activity of the quassinoid NBT-272 in childhood medulloblastoma cells.', BMC CANCER, Jg. 7, S. 19. <http://www.ncbi.nlm.nih.gov/pubmed/17254356?dopt=Citation>

APA

von Bueren, A., André, O., Shalaby, T., Rajtarova, J., Stearns, D., Eberhart, C. G., Helson, L., Arcaro, A., & Grotzer, M. A. (2007). Anti-proliferative activity of the quassinoid NBT-272 in childhood medulloblastoma cells. BMC CANCER, 7, 19. http://www.ncbi.nlm.nih.gov/pubmed/17254356?dopt=Citation

Vancouver

von Bueren A, André O, Shalaby T, Rajtarova J, Stearns D, Eberhart CG et al. Anti-proliferative activity of the quassinoid NBT-272 in childhood medulloblastoma cells. BMC CANCER. 2007;7:19.

Bibtex

@article{c6b9eda811734d22853072107977a8bd,
title = "Anti-proliferative activity of the quassinoid NBT-272 in childhood medulloblastoma cells.",
abstract = "With current treatment strategies, nearly half of all medulloblastoma (MB) patients die from progressive tumors. Accordingly, the identification of novel therapeutic strategies remains a major goal. Deregulation of c-MYC is evident in numerous human cancers. In MB, over-expression of c-MYC has been shown to correlate with anaplasia and unfavorable prognosis. In neuroblastoma--an embryonal tumor with biological similarities to MB--the quassinoid NBT-272 has been demonstrated to inhibit cellular proliferation and to down-regulate c-MYC protein expression.",
author = "{von Bueren}, Andr{\'e} and O Andr{\'e} and Tarek Shalaby and Julia Rajtarova and Duncan Stearns and Eberhart, {Charles G} and Lawrence Helson and Alexandre Arcaro and Grotzer, {Michael A}",
year = "2007",
language = "Deutsch",
volume = "7",
pages = "19",
journal = "BMC CANCER",
issn = "1471-2407",
publisher = "BioMed Central Ltd.",

}

RIS

TY - JOUR

T1 - Anti-proliferative activity of the quassinoid NBT-272 in childhood medulloblastoma cells.

AU - von Bueren, André

AU - André, O

AU - Shalaby, Tarek

AU - Rajtarova, Julia

AU - Stearns, Duncan

AU - Eberhart, Charles G

AU - Helson, Lawrence

AU - Arcaro, Alexandre

AU - Grotzer, Michael A

PY - 2007

Y1 - 2007

N2 - With current treatment strategies, nearly half of all medulloblastoma (MB) patients die from progressive tumors. Accordingly, the identification of novel therapeutic strategies remains a major goal. Deregulation of c-MYC is evident in numerous human cancers. In MB, over-expression of c-MYC has been shown to correlate with anaplasia and unfavorable prognosis. In neuroblastoma--an embryonal tumor with biological similarities to MB--the quassinoid NBT-272 has been demonstrated to inhibit cellular proliferation and to down-regulate c-MYC protein expression.

AB - With current treatment strategies, nearly half of all medulloblastoma (MB) patients die from progressive tumors. Accordingly, the identification of novel therapeutic strategies remains a major goal. Deregulation of c-MYC is evident in numerous human cancers. In MB, over-expression of c-MYC has been shown to correlate with anaplasia and unfavorable prognosis. In neuroblastoma--an embryonal tumor with biological similarities to MB--the quassinoid NBT-272 has been demonstrated to inhibit cellular proliferation and to down-regulate c-MYC protein expression.

M3 - SCORING: Zeitschriftenaufsatz

VL - 7

SP - 19

JO - BMC CANCER

JF - BMC CANCER

SN - 1471-2407

ER -