Analysis of testosterone suppression in men receiving histrelin, a novel GnRH agonist for the treatment of prostate cancer.
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Analysis of testosterone suppression in men receiving histrelin, a novel GnRH agonist for the treatment of prostate cancer. / Bob, Djavan; Schlegel, Peter; Salomon, Georg; Eckersberger, Elisabeth; Sadri, Helen; Graefen, Markus.
in: CAN J UROL, Jahrgang 17, Nr. 4, 4, 2010, S. 5265-5271.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Analysis of testosterone suppression in men receiving histrelin, a novel GnRH agonist for the treatment of prostate cancer.
AU - Bob, Djavan
AU - Schlegel, Peter
AU - Salomon, Georg
AU - Eckersberger, Elisabeth
AU - Sadri, Helen
AU - Graefen, Markus
PY - 2010
Y1 - 2010
N2 - Androgen deprivation therapy (ADT) is the standard care in men with advanced prostate cancer. Continuous testosterone suppression is essential to treatment efficacy. Recently a 1 year depot compound, histrelin, (VANTAS: Orion Pharmaceuticals, Finland; Endo Pharmaceuticals, USA), a gonadotropin-releasing hormone (GnRH) analog, was approved for hormone therapy of prostate cancer. In the present study the therapeutic efficacy of this compound was investigated, in addition to its impact on testosterone values and velocity as well as PSA.
AB - Androgen deprivation therapy (ADT) is the standard care in men with advanced prostate cancer. Continuous testosterone suppression is essential to treatment efficacy. Recently a 1 year depot compound, histrelin, (VANTAS: Orion Pharmaceuticals, Finland; Endo Pharmaceuticals, USA), a gonadotropin-releasing hormone (GnRH) analog, was approved for hormone therapy of prostate cancer. In the present study the therapeutic efficacy of this compound was investigated, in addition to its impact on testosterone values and velocity as well as PSA.
M3 - SCORING: Zeitschriftenaufsatz
VL - 17
SP - 5265
EP - 5271
JO - CAN J UROL
JF - CAN J UROL
SN - 1195-9479
IS - 4
M1 - 4
ER -