Analysis of posaconazole as oral antifungal prophylaxis in pediatric patients under 12 years of age following allogeneic stem cell transplantation.

  • Michaela Döring
  • Carsten Müller
  • Pascal-David Johann
  • Annika Erbacher
  • Astrid Kimmig
  • Carl-Philipp Schwarze
  • Peter Lang
  • Rupert Handgretinger
  • Ingo Müller

Abstract

Pediatric patients undergoing hematopoietic stem cell transplantation (HSCT) are at high risk of acquiring fungal infections. Antifungal prophylaxis shortly after transplantation is therefore indicated, but data for pediatric patients under 12 years of age are scarce. To address this issue, we retrospectively assessed the safety, feasibility, and initial efficacy of prophylactic posaconazole in children.

Bibliografische Daten

OriginalspracheEnglisch
ISSN1471-2334
DOIs
StatusVeröffentlicht - 2012
pubmed 23082876