Analyses of thrombi in acute ischemic stroke: A consensus statement on current knowledge and future directions

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Analyses of thrombi in acute ischemic stroke: A consensus statement on current knowledge and future directions. / De Meyer, Simon F; Andersson, Tommy; Baxter, Blaise; Bendszus, Martin; Brouwer, Patrick; Brinjikji, Waleed; Campbell, Bruce Cv; Costalat, Vincent; Dávalos, Antoni; Demchuk, Andrew; Dippel, Diederik; Fiehler, Jens; Fischer, Urs; Gilvarry, Michael; Gounis, Matthew J; Gralla, Jan; Jansen, Olav; Jovin, Tudor; Kallmes, David; Khatri, Pooja; Lees, Kennedy R; López-Cancio, Elena; Majoie, Charles; Marquering, Henk; Narata, Ana Paula; Nogueira, Raul; Ringleb, Peter; Siddiqui, Adnan; Szikora, István; Vale, David; von Kummer, Rüdiger; Yoo, Albert J; Hacke, Werner; Liebeskind, David S; Clot Summit Group.

in: INT J STROKE, Jahrgang 12, Nr. 6, 08.2017, S. 606-614.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

Harvard

De Meyer, SF, Andersson, T, Baxter, B, Bendszus, M, Brouwer, P, Brinjikji, W, Campbell, BC, Costalat, V, Dávalos, A, Demchuk, A, Dippel, D, Fiehler, J, Fischer, U, Gilvarry, M, Gounis, MJ, Gralla, J, Jansen, O, Jovin, T, Kallmes, D, Khatri, P, Lees, KR, López-Cancio, E, Majoie, C, Marquering, H, Narata, AP, Nogueira, R, Ringleb, P, Siddiqui, A, Szikora, I, Vale, D, von Kummer, R, Yoo, AJ, Hacke, W, Liebeskind, DS & Clot Summit Group 2017, 'Analyses of thrombi in acute ischemic stroke: A consensus statement on current knowledge and future directions', INT J STROKE, Jg. 12, Nr. 6, S. 606-614. https://doi.org/10.1177/1747493017709671

APA

De Meyer, S. F., Andersson, T., Baxter, B., Bendszus, M., Brouwer, P., Brinjikji, W., Campbell, B. C., Costalat, V., Dávalos, A., Demchuk, A., Dippel, D., Fiehler, J., Fischer, U., Gilvarry, M., Gounis, M. J., Gralla, J., Jansen, O., Jovin, T., Kallmes, D., ... Clot Summit Group (2017). Analyses of thrombi in acute ischemic stroke: A consensus statement on current knowledge and future directions. INT J STROKE, 12(6), 606-614. https://doi.org/10.1177/1747493017709671

Vancouver

Bibtex

@article{c87b81bff1124055a281f73b45e5029e,
title = "Analyses of thrombi in acute ischemic stroke: A consensus statement on current knowledge and future directions",
abstract = "Limited data exist on clot composition and detailed characteristics of arterial thrombi associated with large vessel occlusion in acute ischemic stroke. Advances in endovascular thrombectomy and related imaging modalities have created a unique opportunity to analyze thrombi removed from cerebral arteries. Insights into thrombus composition, etiology, physical properties and neurovascular interactions may lead to future advancements in acute ischemic stroke treatment and improved clinical outcomes. Advances in imaging techniques may enhance clot characterization and inform therapeutic decision-making prior to treatment and reveal stroke etiology to guide secondary prevention. Current imaging techniques can provide some information about thrombi, but there remains much to evaluate about relationships that may exist among thrombus composition, occlusion characteristics and treatment outcomes. Improved pathophysiological characterization of clot types, their properties and how these properties change over time, together with clinical correlates from ongoing studies, may facilitate revascularization with thrombolysis and thrombectomy. Interdisciplinary approaches covering clinical, engineering and scientific aspects of thrombus research will be key to advancing the understanding of thrombi and improving acute ischemic stroke therapy. This consensus statement integrates recent research on clots and thrombi retrieved from cerebral arteries and provides a rationale for further analyses, including current opportunities and limitations.",
keywords = "Journal Article",
author = "{De Meyer}, {Simon F} and Tommy Andersson and Blaise Baxter and Martin Bendszus and Patrick Brouwer and Waleed Brinjikji and Campbell, {Bruce Cv} and Vincent Costalat and Antoni D{\'a}valos and Andrew Demchuk and Diederik Dippel and Jens Fiehler and Urs Fischer and Michael Gilvarry and Gounis, {Matthew J} and Jan Gralla and Olav Jansen and Tudor Jovin and David Kallmes and Pooja Khatri and Lees, {Kennedy R} and Elena L{\'o}pez-Cancio and Charles Majoie and Henk Marquering and Narata, {Ana Paula} and Raul Nogueira and Peter Ringleb and Adnan Siddiqui and Istv{\'a}n Szikora and David Vale and {von Kummer}, R{\"u}diger and Yoo, {Albert J} and Werner Hacke and Liebeskind, {David S} and {Clot Summit Group}",
year = "2017",
month = aug,
doi = "10.1177/1747493017709671",
language = "English",
volume = "12",
pages = "606--614",
journal = "INT J STROKE",
issn = "1747-4930",
publisher = "Wiley-Blackwell",
number = "6",

}

RIS

TY - JOUR

T1 - Analyses of thrombi in acute ischemic stroke: A consensus statement on current knowledge and future directions

AU - De Meyer, Simon F

AU - Andersson, Tommy

AU - Baxter, Blaise

AU - Bendszus, Martin

AU - Brouwer, Patrick

AU - Brinjikji, Waleed

AU - Campbell, Bruce Cv

AU - Costalat, Vincent

AU - Dávalos, Antoni

AU - Demchuk, Andrew

AU - Dippel, Diederik

AU - Fiehler, Jens

AU - Fischer, Urs

AU - Gilvarry, Michael

AU - Gounis, Matthew J

AU - Gralla, Jan

AU - Jansen, Olav

AU - Jovin, Tudor

AU - Kallmes, David

AU - Khatri, Pooja

AU - Lees, Kennedy R

AU - López-Cancio, Elena

AU - Majoie, Charles

AU - Marquering, Henk

AU - Narata, Ana Paula

AU - Nogueira, Raul

AU - Ringleb, Peter

AU - Siddiqui, Adnan

AU - Szikora, István

AU - Vale, David

AU - von Kummer, Rüdiger

AU - Yoo, Albert J

AU - Hacke, Werner

AU - Liebeskind, David S

AU - Clot Summit Group

PY - 2017/8

Y1 - 2017/8

N2 - Limited data exist on clot composition and detailed characteristics of arterial thrombi associated with large vessel occlusion in acute ischemic stroke. Advances in endovascular thrombectomy and related imaging modalities have created a unique opportunity to analyze thrombi removed from cerebral arteries. Insights into thrombus composition, etiology, physical properties and neurovascular interactions may lead to future advancements in acute ischemic stroke treatment and improved clinical outcomes. Advances in imaging techniques may enhance clot characterization and inform therapeutic decision-making prior to treatment and reveal stroke etiology to guide secondary prevention. Current imaging techniques can provide some information about thrombi, but there remains much to evaluate about relationships that may exist among thrombus composition, occlusion characteristics and treatment outcomes. Improved pathophysiological characterization of clot types, their properties and how these properties change over time, together with clinical correlates from ongoing studies, may facilitate revascularization with thrombolysis and thrombectomy. Interdisciplinary approaches covering clinical, engineering and scientific aspects of thrombus research will be key to advancing the understanding of thrombi and improving acute ischemic stroke therapy. This consensus statement integrates recent research on clots and thrombi retrieved from cerebral arteries and provides a rationale for further analyses, including current opportunities and limitations.

AB - Limited data exist on clot composition and detailed characteristics of arterial thrombi associated with large vessel occlusion in acute ischemic stroke. Advances in endovascular thrombectomy and related imaging modalities have created a unique opportunity to analyze thrombi removed from cerebral arteries. Insights into thrombus composition, etiology, physical properties and neurovascular interactions may lead to future advancements in acute ischemic stroke treatment and improved clinical outcomes. Advances in imaging techniques may enhance clot characterization and inform therapeutic decision-making prior to treatment and reveal stroke etiology to guide secondary prevention. Current imaging techniques can provide some information about thrombi, but there remains much to evaluate about relationships that may exist among thrombus composition, occlusion characteristics and treatment outcomes. Improved pathophysiological characterization of clot types, their properties and how these properties change over time, together with clinical correlates from ongoing studies, may facilitate revascularization with thrombolysis and thrombectomy. Interdisciplinary approaches covering clinical, engineering and scientific aspects of thrombus research will be key to advancing the understanding of thrombi and improving acute ischemic stroke therapy. This consensus statement integrates recent research on clots and thrombi retrieved from cerebral arteries and provides a rationale for further analyses, including current opportunities and limitations.

KW - Journal Article

U2 - 10.1177/1747493017709671

DO - 10.1177/1747493017709671

M3 - SCORING: Journal article

C2 - 28534706

VL - 12

SP - 606

EP - 614

JO - INT J STROKE

JF - INT J STROKE

SN - 1747-4930

IS - 6

ER -