An unexpected role of steroid on podocytes: from zebrafish to human nephrotic syndrome?

Abstract

In this issue of Kidney International, Jobst-Schwan et al. developed a zebrafish model of MAGI2-deficiency, which recapitulates findings of human nephrotic syndrome due to MAGI2 mutations. The authors use this model system to screen for drugs that might target and alleviate MAGI2-associated nephrotic syndrome pathways. The scientific context of this publication and the significance of its key findings are discussed in this commentary.

Bibliografische Daten

OriginalspracheEnglisch
ISSN0085-2538
DOIs
StatusVeröffentlicht - 05.2019

Anmerkungen des Dekanats

Copyright © 2019 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.

PubMed 31010473