An unexpected role of steroid on podocytes: from zebrafish to human nephrotic syndrome?
Beteiligte Einrichtungen
Abstract
In this issue of Kidney International, Jobst-Schwan et al. developed a zebrafish model of MAGI2-deficiency, which recapitulates findings of human nephrotic syndrome due to MAGI2 mutations. The authors use this model system to screen for drugs that might target and alleviate MAGI2-associated nephrotic syndrome pathways. The scientific context of this publication and the significance of its key findings are discussed in this commentary.
Bibliografische Daten
Originalsprache | Englisch |
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ISSN | 0085-2538 |
DOIs | |
Status | Veröffentlicht - 05.2019 |
Anmerkungen des Dekanats
Copyright © 2019 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.
PubMed | 31010473 |
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