An outbreak of Shiga toxin-producing Escherichia coli O104:H4 hemolytic uremic syndrome in Germany: presentation and short-term outcome in children.

  • Sebastian Loos
  • Thurid Ahlenstiel
  • Brigitta Kranz
  • Hagen Staude
  • Lars Pape
  • Christoph Härtel
  • Udo Vester
  • Laura Buchtala
  • Kerstin Benz
  • Bernd Hoppe
  • Ortraud Beringer
  • Martin Krause
  • Dominik Müller
  • Martin Pohl
  • Johanna Lemke
  • Georg Hillebrand
  • Martin Kreuzer
  • Jens König
  • Marianne Wigger
  • Martin Konrad
  • Dieter Haffner
  • Jun Oh
  • Markus J. Kemper

Abstract

In May and June 2011 the largest known outbreak of hemolytic uremic syndrome (HUS) occurred in northern Germany. Because, quite unusually, a large number of adults was affected and the causative Escherichia coli strain, serotype O104:H4, showed an atypical virulence factor pattern, it was speculated that this outbreak was associated with an aggressive course and an unfavorable prognosis also in children.

Bibliografische Daten

OriginalspracheEnglisch
Aufsatznummer6
ISSN1058-4838
StatusVeröffentlicht - 2012
pubmed 22670043