Alterations of time-intervals of the ductus venosus and atrioventricular flow velocity waveforms in growth restricted fetuses
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Alterations of time-intervals of the ductus venosus and atrioventricular flow velocity waveforms in growth restricted fetuses. / Wada, N; Tachibana, D; Kurihara, Y; Nakagawa, K; Nakano, A; Terada, H; Tanaka, K; Fukui, M; Koyama, M; Hecher, K.
in: ULTRASOUND OBST GYN, Jahrgang 46, Nr. 2, 08.2015, S. 221-226.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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T1 - Alterations of time-intervals of the ductus venosus and atrioventricular flow velocity waveforms in growth restricted fetuses
AU - Wada, N
AU - Tachibana, D
AU - Kurihara, Y
AU - Nakagawa, K
AU - Nakano, A
AU - Terada, H
AU - Tanaka, K
AU - Fukui, M
AU - Koyama, M
AU - Hecher, K
N1 - This article is protected by copyright. All rights reserved.
PY - 2015/8
Y1 - 2015/8
N2 - OBJECTIVE: To investigate time intervals of the ductus venosus (DV) flow velocity waveform (FVW) and those of cardiac cycle which correspond with each DV-FVW component in fetuses complicated with intrauterine growth restriction (IUGR) due to placental insufficiency.METHODS: Time intervals for systolic (S) and diastolic (D) components were measured in DV-FVW as following: SDV , from the nadir of the a-wave during atrial contraction to the nadir between S-wave and D-wave; DDV , from the nadir between S-wave and D-wave to the nadir of a-wave. Regarding the cardiac cycles, the following variables were measured in ventricular inflow through tricuspid valve (TV) and mitral valve (MV): STV and SMV , from the second peak of ventricular inflow caused by atrial contraction (A-wave) to the opening of the atrio-ventricular valve; DTV and DMV , from the opening of the atrio-ventricular valve to the peak of A-wave. All variables were statistically analyzed using z-score.RESULTS: The data were obtained from 249 normal fetuses and 26 IUGR fetuses. Compared to normal fetuses, SDV showed a significant decrease (P < 0.001), while DDV increased significantly (P < 0.001) in the IUGR group. Regarding the cardiac cycles, STV and SMV decreased significantly (P = 0.014 and P < 0.001, respectively), and DTV and DMV showed significant increases (P = 0.008 and P = 0.002, respectively) in IUGR fetuses.CONCLUSION: Time interval alterations of DV-FVW in growth restricted fetuses reflect the hemodynamic events caused by placental insufficiency.
AB - OBJECTIVE: To investigate time intervals of the ductus venosus (DV) flow velocity waveform (FVW) and those of cardiac cycle which correspond with each DV-FVW component in fetuses complicated with intrauterine growth restriction (IUGR) due to placental insufficiency.METHODS: Time intervals for systolic (S) and diastolic (D) components were measured in DV-FVW as following: SDV , from the nadir of the a-wave during atrial contraction to the nadir between S-wave and D-wave; DDV , from the nadir between S-wave and D-wave to the nadir of a-wave. Regarding the cardiac cycles, the following variables were measured in ventricular inflow through tricuspid valve (TV) and mitral valve (MV): STV and SMV , from the second peak of ventricular inflow caused by atrial contraction (A-wave) to the opening of the atrio-ventricular valve; DTV and DMV , from the opening of the atrio-ventricular valve to the peak of A-wave. All variables were statistically analyzed using z-score.RESULTS: The data were obtained from 249 normal fetuses and 26 IUGR fetuses. Compared to normal fetuses, SDV showed a significant decrease (P < 0.001), while DDV increased significantly (P < 0.001) in the IUGR group. Regarding the cardiac cycles, STV and SMV decreased significantly (P = 0.014 and P < 0.001, respectively), and DTV and DMV showed significant increases (P = 0.008 and P = 0.002, respectively) in IUGR fetuses.CONCLUSION: Time interval alterations of DV-FVW in growth restricted fetuses reflect the hemodynamic events caused by placental insufficiency.
U2 - 10.1002/uog.14717
DO - 10.1002/uog.14717
M3 - SCORING: Journal article
C2 - 25366537
VL - 46
SP - 221
EP - 226
JO - ULTRASOUND OBST GYN
JF - ULTRASOUND OBST GYN
SN - 0960-7692
IS - 2
ER -