Algorithm for the automatic computation of the modified Anderson-Wilkins acuteness score of ischemia from the pre-hospital ECG in ST-segment elevation myocardial infarction
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Algorithm for the automatic computation of the modified Anderson-Wilkins acuteness score of ischemia from the pre-hospital ECG in ST-segment elevation myocardial infarction. / Fakhri, Yama; Sejersten, Maria; Schoos, Mikkel Malby; Melgaard, Jacob; Graff, Claus; Wagner, Galen S; Clemmensen, Peter; Kastrup, Jens.
in: J ELECTROCARDIOL, Jahrgang 50, Nr. 1, 28.11.2016, S. 97-101.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Algorithm for the automatic computation of the modified Anderson-Wilkins acuteness score of ischemia from the pre-hospital ECG in ST-segment elevation myocardial infarction
AU - Fakhri, Yama
AU - Sejersten, Maria
AU - Schoos, Mikkel Malby
AU - Melgaard, Jacob
AU - Graff, Claus
AU - Wagner, Galen S
AU - Clemmensen, Peter
AU - Kastrup, Jens
N1 - Copyright © 2016 Elsevier Inc. All rights reserved.
PY - 2016/11/28
Y1 - 2016/11/28
N2 - BACKGROUND: The acuteness score (based on the modified Anderson-Wilkins score) estimates the acuteness of ischemia based on ST-segment, Q-wave and T-wave measurements obtained from the electrocardiogram (ECG) in patients with ST Elevation Myocardial Infarction (STEMI). The score (range 1 (least acute) to 4 (most acute)) identifies patients with substantial myocardial salvage potential regardless of patient reported symptom duration. However, due to the complexity of the score, it is not used in clinical practice. Therefore, we aimed to develop a reliable algorithm that automatically computes the acuteness score.METHODS: We scored 50 pre-hospital ECGs from STEMI patients, manually and by the automated algorithm. We assessed the reliability test between the manual and automated algorithm by interclass correlation coefficient (ICC) and Bland-Altman plot.RESULTS: The ICC was 0.84 (95% CI 0.72-0.91), P<0.0001. The mean difference between manual and automated acuteness score was 0.17±0.66. In only two cases, there was a major disagreement between the two scores. There was an excellent agreement between the scores for the remaining 48 ECGs, all within the upper (1.46) and lower (-1.12) limits of agreement.CONCLUSION: In conclusion, we have developed an automated algorithm for measurement of the modified Anderson-Wilkins ECG acuteness score from the pre-hospital ECG in STEMI patients. This automated algorithm is highly reliable, can be applied in daily practice for research purposes and may be implemented in commercial automated ECG analysis programs to achieve practical use for decision support in the acute phase of STEMI.
AB - BACKGROUND: The acuteness score (based on the modified Anderson-Wilkins score) estimates the acuteness of ischemia based on ST-segment, Q-wave and T-wave measurements obtained from the electrocardiogram (ECG) in patients with ST Elevation Myocardial Infarction (STEMI). The score (range 1 (least acute) to 4 (most acute)) identifies patients with substantial myocardial salvage potential regardless of patient reported symptom duration. However, due to the complexity of the score, it is not used in clinical practice. Therefore, we aimed to develop a reliable algorithm that automatically computes the acuteness score.METHODS: We scored 50 pre-hospital ECGs from STEMI patients, manually and by the automated algorithm. We assessed the reliability test between the manual and automated algorithm by interclass correlation coefficient (ICC) and Bland-Altman plot.RESULTS: The ICC was 0.84 (95% CI 0.72-0.91), P<0.0001. The mean difference between manual and automated acuteness score was 0.17±0.66. In only two cases, there was a major disagreement between the two scores. There was an excellent agreement between the scores for the remaining 48 ECGs, all within the upper (1.46) and lower (-1.12) limits of agreement.CONCLUSION: In conclusion, we have developed an automated algorithm for measurement of the modified Anderson-Wilkins ECG acuteness score from the pre-hospital ECG in STEMI patients. This automated algorithm is highly reliable, can be applied in daily practice for research purposes and may be implemented in commercial automated ECG analysis programs to achieve practical use for decision support in the acute phase of STEMI.
KW - Acute Disease
KW - Algorithms
KW - Diagnosis, Computer-Assisted/methods
KW - Electrocardiography/methods
KW - Emergency Medical Services/methods
KW - Female
KW - Humans
KW - Male
KW - Middle Aged
KW - Observer Variation
KW - Pattern Recognition, Automated/methods
KW - Reproducibility of Results
KW - ST Elevation Myocardial Infarction/diagnosis
KW - Sensitivity and Specificity
KW - Severity of Illness Index
U2 - 10.1016/j.jelectrocard.2016.11.005
DO - 10.1016/j.jelectrocard.2016.11.005
M3 - SCORING: Journal article
C2 - 27889057
VL - 50
SP - 97
EP - 101
JO - J ELECTROCARDIOL
JF - J ELECTROCARDIOL
SN - 0022-0736
IS - 1
ER -