PortalPublikationenAdult and pediatric medulloblastomas are genetically distinc...

Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification.

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  • Andrey Korshunov
  • Marc Remke
  • Wiebke Werft
  • Axel Benner
  • Marina Ryzhova
  • Hendrik Witt
  • Dominik Sturm
  • Andrea Wittmann
  • Anna Schöttler
  • Jörg Felsberg
  • Guido Reifenberger
  • Stefan Rutkowski
  • Wolfram Scheurlen
  • Andreas E Kulozik
  • Andreas von Deimling
  • Peter Lichter
  • Stefan M Pfister

Beteiligte Einrichtungen

Abstract

Medulloblastoma (MB) is the most common malignant brain tumor in children, whereas it rarely presents in adults. We aimed to identify genetic aberrations in 146 adult MBs to evaluate age-dependent differences in tumor biology and adapt age-specific risk stratification models.

Bibliografische Daten

OriginalspracheDeutsch
Aufsatznummer18
ISSN0732-183X
StatusVeröffentlicht - 2010
pubmed 20479417