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Acute liver failure following minocycline treatment - a case report and review of the literature.

Standard

Acute liver failure following minocycline treatment - a case report and review of the literature. / Kuhn, Anne; Weiler-Normann, Christina; Schramm, Christoph; Kluge, Stefan; Behne, Martin; Lohse, Ansgar W.; Benten, Daniel.

in: Z GASTROENTEROL, Jahrgang 50, Nr. 8, 8, 2012, S. 771-775.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Kuhn, A, Weiler-Normann, C, Schramm, C, Kluge, S, Behne, M, Lohse, AW & Benten, D 2012, 'Acute liver failure following minocycline treatment - a case report and review of the literature.', Z GASTROENTEROL, Jg. 50, Nr. 8, 8, S. 771-775. <http://www.ncbi.nlm.nih.gov/pubmed/22895906?dopt=Citation>

APA

Kuhn, A., Weiler-Normann, C., Schramm, C., Kluge, S., Behne, M., Lohse, A. W., & Benten, D. (2012). Acute liver failure following minocycline treatment - a case report and review of the literature. Z GASTROENTEROL, 50(8), 771-775. [8]. http://www.ncbi.nlm.nih.gov/pubmed/22895906?dopt=Citation

Vancouver

Kuhn A, Weiler-Normann C, Schramm C, Kluge S, Behne M, Lohse AW et al. Acute liver failure following minocycline treatment - a case report and review of the literature. Z GASTROENTEROL. 2012;50(8):771-775. 8.

Bibtex

@article{4e741ec613ad4a51af0622113181aeab,
title = "Acute liver failure following minocycline treatment - a case report and review of the literature.",
abstract = "We present the case of a 23-year-old female patient with acute liver failure following intake of minocycline. This patient had severe hypereosinophilia and massively increased IgE levels. Experimental studies in this case revealed elevated IFN-?-, as well as TNF-?-producing CD4+ and CD8+ T-cells after in vitro stimulation with minocycline, indicating a type I/IgE-mediated as well as type II/cytotoxic reaction in the pathogenesis of minocycline-induced liver failure. Although mild forms of liver involvement are well known side effects of minocycline, only 8 cases with acute liver failure have been reported, and we present a review of all cases.",
keywords = "Diagnosis, Differential, Humans, Female, Young Adult, Anti-Bacterial Agents/adverse effects, Liver Failure, Acute/*chemically induced/diagnosis/*prevention & control, Minocycline/*adverse effects, Diagnosis, Differential, Humans, Female, Young Adult, Anti-Bacterial Agents/adverse effects, Liver Failure, Acute/*chemically induced/diagnosis/*prevention & control, Minocycline/*adverse effects",
author = "Anne Kuhn and Christina Weiler-Normann and Christoph Schramm and Stefan Kluge and Martin Behne and Lohse, {Ansgar W.} and Daniel Benten",
year = "2012",
language = "English",
volume = "50",
pages = "771--775",
journal = "Z GASTROENTEROL",
issn = "0044-2771",
publisher = "Karl Demeter Verlag GmbH",
number = "8",

}

RIS

TY - JOUR

T1 - Acute liver failure following minocycline treatment - a case report and review of the literature.

AU - Kuhn, Anne

AU - Weiler-Normann, Christina

AU - Schramm, Christoph

AU - Kluge, Stefan

AU - Behne, Martin

AU - Lohse, Ansgar W.

AU - Benten, Daniel

PY - 2012

Y1 - 2012

N2 - We present the case of a 23-year-old female patient with acute liver failure following intake of minocycline. This patient had severe hypereosinophilia and massively increased IgE levels. Experimental studies in this case revealed elevated IFN-?-, as well as TNF-?-producing CD4+ and CD8+ T-cells after in vitro stimulation with minocycline, indicating a type I/IgE-mediated as well as type II/cytotoxic reaction in the pathogenesis of minocycline-induced liver failure. Although mild forms of liver involvement are well known side effects of minocycline, only 8 cases with acute liver failure have been reported, and we present a review of all cases.

AB - We present the case of a 23-year-old female patient with acute liver failure following intake of minocycline. This patient had severe hypereosinophilia and massively increased IgE levels. Experimental studies in this case revealed elevated IFN-?-, as well as TNF-?-producing CD4+ and CD8+ T-cells after in vitro stimulation with minocycline, indicating a type I/IgE-mediated as well as type II/cytotoxic reaction in the pathogenesis of minocycline-induced liver failure. Although mild forms of liver involvement are well known side effects of minocycline, only 8 cases with acute liver failure have been reported, and we present a review of all cases.

KW - Diagnosis, Differential

KW - Humans

KW - Female

KW - Young Adult

KW - Anti-Bacterial Agents/adverse effects

KW - Liver Failure, Acute/chemically induced/diagnosis/prevention & control

KW - Minocycline/adverse effects

KW - Diagnosis, Differential

KW - Humans

KW - Female

KW - Young Adult

KW - Anti-Bacterial Agents/adverse effects

KW - Liver Failure, Acute/chemically induced/diagnosis/prevention & control

KW - Minocycline/adverse effects

M3 - SCORING: Journal article

VL - 50

SP - 771

EP - 775

JO - Z GASTROENTEROL

JF - Z GASTROENTEROL

SN - 0044-2771

IS - 8

M1 - 8

ER -