Across scales: novel insights into kidney health and disease by structural biology

Nicola M Tomas; Simon A Mortensen; Matthias Wilmanns; Tobias B Huber

doi:10.1016/j.kint.2021.03.042

Across scales: novel insights into kidney health and disease by structural biology

Standard

Across scales: novel insights into kidney health and disease by structural biology. / Tomas, Nicola M; Mortensen, Simon A; Wilmanns, Matthias; Huber, Tobias B.

in: KIDNEY INT, Jahrgang 100, Nr. 2, 08.2021, S. 281-288.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung

Harvard

Tomas, NM, Mortensen, SA, Wilmanns, M & Huber, TB 2021, 'Across scales: novel insights into kidney health and disease by structural biology', KIDNEY INT, Jg. 100, Nr. 2, S. 281-288. https://doi.org/10.1016/j.kint.2021.03.042

APA

Tomas, N. M., Mortensen, S. A., Wilmanns, M., & Huber, T. B. (2021). Across scales: novel insights into kidney health and disease by structural biology. KIDNEY INT, 100(2), 281-288. https://doi.org/10.1016/j.kint.2021.03.042

Vancouver

Tomas NM, Mortensen SA, Wilmanns M, Huber TB. Across scales: novel insights into kidney health and disease by structural biology. KIDNEY INT. 2021 Aug;100(2):281-288. https://doi.org/10.1016/j.kint.2021.03.042

Bibtex

@article{f61696b7a74d47ca8b64c34ffac9cf45,

title = "Across scales: novel insights into kidney health and disease by structural biology",

abstract = "Over the past decades, structural biology methods such as X-ray crystallography and cryo-electron microscopy have been increasingly used to study protein functions, molecular interactions, physiological processes, and disease mechanisms. This review outlines a selection of structural biology methods, highlights recent examples of how structural analyses have contributed to a more profound understanding of the machinery of life, and gives a perspective on how these methods can be applied to investigate functions of kidney molecules and pathogenic mechanisms of renal diseases.",

keywords = "Biology, Cryoelectron Microscopy, Crystallography, X-Ray, Kidney, Proteins",

author = "Tomas, {Nicola M} and Mortensen, {Simon A} and Matthias Wilmanns and Huber, {Tobias B}",

year = "2021",

month = aug,

doi = "10.1016/j.kint.2021.03.042",

language = "English",

volume = "100",

pages = "281--288",

journal = "KIDNEY INT",

issn = "0085-2538",

publisher = "NATURE PUBLISHING GROUP",

number = "2",

}

RIS

TY - JOUR

T1 - Across scales: novel insights into kidney health and disease by structural biology

AU - Tomas, Nicola M

AU - Mortensen, Simon A

AU - Wilmanns, Matthias

AU - Huber, Tobias B

PY - 2021/8

Y1 - 2021/8

N2 - Over the past decades, structural biology methods such as X-ray crystallography and cryo-electron microscopy have been increasingly used to study protein functions, molecular interactions, physiological processes, and disease mechanisms. This review outlines a selection of structural biology methods, highlights recent examples of how structural analyses have contributed to a more profound understanding of the machinery of life, and gives a perspective on how these methods can be applied to investigate functions of kidney molecules and pathogenic mechanisms of renal diseases.

AB - Over the past decades, structural biology methods such as X-ray crystallography and cryo-electron microscopy have been increasingly used to study protein functions, molecular interactions, physiological processes, and disease mechanisms. This review outlines a selection of structural biology methods, highlights recent examples of how structural analyses have contributed to a more profound understanding of the machinery of life, and gives a perspective on how these methods can be applied to investigate functions of kidney molecules and pathogenic mechanisms of renal diseases.

KW - Biology

KW - Cryoelectron Microscopy

KW - Crystallography, X-Ray

KW - Kidney

KW - Proteins

U2 - 10.1016/j.kint.2021.03.042

DO - 10.1016/j.kint.2021.03.042

M3 - SCORING: Review article

C2 - 33940110

VL - 100

SP - 281

EP - 288

JO - KIDNEY INT

JF - KIDNEY INT

SN - 0085-2538

IS - 2

ER -