Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinoma.
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Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinoma. / Mansour Khalfallah, Wael Yassin; Bogdanova, Natalia V; Kasten-Pisula, Ulla; Rieckmann, Thorsten; Köcher, Sabrina; Borgmann, Kerstin; Baumann, Michael; Krause, Mechtild; Petersen, Cordula; Hu, Hailiang; Gatti, Richard A; Dikomey, Ekkehard; Dörk, Thilo; Dahm-Daphi, Jochen.
in: RADIOTHER ONCOL, Jahrgang 106, Nr. 1, 1, 2013, S. 147-154.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinoma.
AU - Mansour Khalfallah, Wael Yassin
AU - Bogdanova, Natalia V
AU - Kasten-Pisula, Ulla
AU - Rieckmann, Thorsten
AU - Köcher, Sabrina
AU - Borgmann, Kerstin
AU - Baumann, Michael
AU - Krause, Mechtild
AU - Petersen, Cordula
AU - Hu, Hailiang
AU - Gatti, Richard A
AU - Dikomey, Ekkehard
AU - Dörk, Thilo
AU - Dahm-Daphi, Jochen
PY - 2013
Y1 - 2013
N2 - Cellular and clinical sensitivity to ionizing radiation (IR) is determined by DNA double-strand breaks (DSB) repair. Here, we investigate the molecular mechanism underlying the extreme response of a head and neck tumor case (SKX) to standard radiotherapy.
AB - Cellular and clinical sensitivity to ionizing radiation (IR) is determined by DNA double-strand breaks (DSB) repair. Here, we investigate the molecular mechanism underlying the extreme response of a head and neck tumor case (SKX) to standard radiotherapy.
M3 - SCORING: Journal article
VL - 106
SP - 147
EP - 154
JO - RADIOTHER ONCOL
JF - RADIOTHER ONCOL
SN - 0167-8140
IS - 1
M1 - 1
ER -
