A transcription-dependent increase in miniature EPSC frequency accompanies late-phase plasticity in cultured hippocampal neurons.

J. Simon Wiegert; Frank Hofmann; Hilmar Bading; C Peter Bengtson

A transcription-dependent increase in miniature EPSC frequency accompanies late-phase plasticity in cultured hippocampal neurons.

Standard

A transcription-dependent increase in miniature EPSC frequency accompanies late-phase plasticity in cultured hippocampal neurons. / Wiegert, J. Simon; Hofmann, Frank; Bading, Hilmar; Bengtson, C Peter.

in: BMC NEUROSCI, Jahrgang 10, 2009, S. 124.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Wiegert, JS, Hofmann, F, Bading, H & Bengtson, CP 2009, 'A transcription-dependent increase in miniature EPSC frequency accompanies late-phase plasticity in cultured hippocampal neurons.', BMC NEUROSCI, Jg. 10, S. 124. <http://www.ncbi.nlm.nih.gov/pubmed/19788723?dopt=Citation>

APA

Wiegert, J. S., Hofmann, F., Bading, H., & Bengtson, C. P. (2009). A transcription-dependent increase in miniature EPSC frequency accompanies late-phase plasticity in cultured hippocampal neurons. BMC NEUROSCI, 10, 124. http://www.ncbi.nlm.nih.gov/pubmed/19788723?dopt=Citation

Vancouver

Wiegert JS, Hofmann F, Bading H, Bengtson CP. A transcription-dependent increase in miniature EPSC frequency accompanies late-phase plasticity in cultured hippocampal neurons. BMC NEUROSCI. 2009;10:124.

Bibtex

@article{0748f55d5c4144179ddf41954e162462,

title = "A transcription-dependent increase in miniature EPSC frequency accompanies late-phase plasticity in cultured hippocampal neurons.",

abstract = "The magnitude and longevity of synaptic activity-induced changes in synaptic efficacy is quantified by measuring evoked responses whose potentiation requires gene transcription to persist for more than 2-3 hours. While miniature EPSCs (mEPSCs) are also increased in amplitude and/or frequency during long-term potentiation (LTP), it is not known how long such changes persist or whether gene transcription is required.",

keywords = "Animals, Time Factors, Cells, Cultured, Rats, Rats, Sprague-Dawley, Blotting, Western, Animals, Newborn, Patch-Clamp Techniques, Action Potentials/physiology, Excitatory Postsynaptic Potentials/*genetics/physiology, Hippocampus/cytology/metabolism/*physiology, Miniature Postsynaptic Potentials/*genetics/physiology, Nerve Net/metabolism/physiology, Neuronal Plasticity/*genetics/physiology, Neurons/cytology/metabolism/*physiology, Proto-Oncogene Proteins c-fos/metabolism, Synaptic Transmission/genetics/physiology, Transcription, Genetic/*physiology, Animals, Time Factors, Cells, Cultured, Rats, Rats, Sprague-Dawley, Blotting, Western, Animals, Newborn, Patch-Clamp Techniques, Action Potentials/physiology, Excitatory Postsynaptic Potentials/*genetics/physiology, Hippocampus/cytology/metabolism/*physiology, Miniature Postsynaptic Potentials/*genetics/physiology, Nerve Net/metabolism/physiology, Neuronal Plasticity/*genetics/physiology, Neurons/cytology/metabolism/*physiology, Proto-Oncogene Proteins c-fos/metabolism, Synaptic Transmission/genetics/physiology, Transcription, Genetic/*physiology",

author = "Wiegert, {J. Simon} and Frank Hofmann and Hilmar Bading and Bengtson, {C Peter}",

year = "2009",

language = "English",

volume = "10",

pages = "124",

journal = "BMC NEUROSCI",

issn = "1471-2202",

publisher = "BioMed Central Ltd.",

}

RIS

TY - JOUR

T1 - A transcription-dependent increase in miniature EPSC frequency accompanies late-phase plasticity in cultured hippocampal neurons.

AU - Wiegert, J. Simon

AU - Hofmann, Frank

AU - Bading, Hilmar

AU - Bengtson, C Peter

PY - 2009

Y1 - 2009

N2 - The magnitude and longevity of synaptic activity-induced changes in synaptic efficacy is quantified by measuring evoked responses whose potentiation requires gene transcription to persist for more than 2-3 hours. While miniature EPSCs (mEPSCs) are also increased in amplitude and/or frequency during long-term potentiation (LTP), it is not known how long such changes persist or whether gene transcription is required.

AB - The magnitude and longevity of synaptic activity-induced changes in synaptic efficacy is quantified by measuring evoked responses whose potentiation requires gene transcription to persist for more than 2-3 hours. While miniature EPSCs (mEPSCs) are also increased in amplitude and/or frequency during long-term potentiation (LTP), it is not known how long such changes persist or whether gene transcription is required.

KW - Animals

KW - Time Factors

KW - Cells, Cultured

KW - Rats

KW - Rats, Sprague-Dawley

KW - Blotting, Western

KW - Animals, Newborn

KW - Patch-Clamp Techniques

KW - Action Potentials/physiology

KW - Excitatory Postsynaptic Potentials/genetics/physiology

KW - Hippocampus/cytology/metabolism/physiology

KW - Miniature Postsynaptic Potentials/genetics/physiology

KW - Nerve Net/metabolism/physiology

KW - Neuronal Plasticity/genetics/physiology

KW - Neurons/cytology/metabolism/physiology

KW - Proto-Oncogene Proteins c-fos/metabolism

KW - Synaptic Transmission/genetics/physiology

KW - Transcription, Genetic/physiology