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A seven-marker signature and clinical outcome in malignant melanoma: a large-scale tissue-microarray study with two independent patient cohorts.

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A seven-marker signature and clinical outcome in malignant melanoma: a large-scale tissue-microarray study with two independent patient cohorts. / Meyer, Stefanie; Fuchs, Thomas J; Bosserhoff, Anja K; Hofstädter, Ferdinand; Pauer, Armin; Roth, Volker; Buhmann, Joachim M; Moll, Ingrid; Anagnostou, Nikos; Brandner, Johanna; Ikenberg, Kristian; Moch, Holger; Landthaler, Michael; Vogt, Thomas; Wild, Peter J.

in: PLOS ONE, Jahrgang 7, Nr. 6, 6, 2012, S. 38222.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Meyer, S, Fuchs, TJ, Bosserhoff, AK, Hofstädter, F, Pauer, A, Roth, V, Buhmann, JM, Moll, I, Anagnostou, N, Brandner, J, Ikenberg, K, Moch, H, Landthaler, M, Vogt, T & Wild, PJ 2012, 'A seven-marker signature and clinical outcome in malignant melanoma: a large-scale tissue-microarray study with two independent patient cohorts.', PLOS ONE, Jg. 7, Nr. 6, 6, S. 38222. https://doi.org/10.1371/journal.pone.0038222

APA

Meyer, S., Fuchs, T. J., Bosserhoff, A. K., Hofstädter, F., Pauer, A., Roth, V., Buhmann, J. M., Moll, I., Anagnostou, N., Brandner, J., Ikenberg, K., Moch, H., Landthaler, M., Vogt, T., & Wild, P. J. (2012). A seven-marker signature and clinical outcome in malignant melanoma: a large-scale tissue-microarray study with two independent patient cohorts. PLOS ONE, 7(6), 38222. [6]. https://doi.org/10.1371/journal.pone.0038222

Vancouver

Meyer S, Fuchs TJ, Bosserhoff AK, Hofstädter F, Pauer A, Roth V et al. A seven-marker signature and clinical outcome in malignant melanoma: a large-scale tissue-microarray study with two independent patient cohorts. PLOS ONE. 2012;7(6):38222. 6. https://doi.org/10.1371/journal.pone.0038222

Bibtex

@article{66bfb0b6cda64d078fbf49ecdcc9c36d,
title = "A seven-marker signature and clinical outcome in malignant melanoma: a large-scale tissue-microarray study with two independent patient cohorts.",
abstract = "Current staging methods such as tumor thickness, ulceration and invasion of the sentinel node are known to be prognostic parameters in patients with malignant melanoma (MM). However, predictive molecular marker profiles for risk stratification and therapy optimization are not yet available for routine clinical assessment.",
keywords = "Adult, Humans, Male, Aged, Female, Middle Aged, Treatment Outcome, Cohort Studies, Prognosis, Proportional Hazards Models, Cells, Cultured, Cell Line, Tumor, Kaplan-Meier Estimate, Tumor Markers, Biological/*metabolism, Antigens, CD20/metabolism, Cyclooxygenase 2/metabolism, Immunohistochemistry/statistics & numerical data, Melanoma/*metabolism/pathology/therapy, PTEN Phosphohydrolase/metabolism, Purine-Nucleoside Phosphorylase/metabolism, Skin Neoplasms/*metabolism/pathology/therapy, Tissue Array Analysis/*methods, bcl-2-Associated X Protein/metabolism, bcl-X Protein/metabolism, beta Catenin/metabolism, Adult, Humans, Male, Aged, Female, Middle Aged, Treatment Outcome, Cohort Studies, Prognosis, Proportional Hazards Models, Cells, Cultured, Cell Line, Tumor, Kaplan-Meier Estimate, Tumor Markers, Biological/*metabolism, Antigens, CD20/metabolism, Cyclooxygenase 2/metabolism, Immunohistochemistry/statistics & numerical data, Melanoma/*metabolism/pathology/therapy, PTEN Phosphohydrolase/metabolism, Purine-Nucleoside Phosphorylase/metabolism, Skin Neoplasms/*metabolism/pathology/therapy, Tissue Array Analysis/*methods, bcl-2-Associated X Protein/metabolism, bcl-X Protein/metabolism, beta Catenin/metabolism",
author = "Stefanie Meyer and Fuchs, {Thomas J} and Bosserhoff, {Anja K} and Ferdinand Hofst{\"a}dter and Armin Pauer and Volker Roth and Buhmann, {Joachim M} and Ingrid Moll and Nikos Anagnostou and Johanna Brandner and Kristian Ikenberg and Holger Moch and Michael Landthaler and Thomas Vogt and Wild, {Peter J}",
year = "2012",
doi = "10.1371/journal.pone.0038222",
language = "English",
volume = "7",
pages = "38222",
journal = "PLOS ONE",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "6",

}

RIS

TY - JOUR

T1 - A seven-marker signature and clinical outcome in malignant melanoma: a large-scale tissue-microarray study with two independent patient cohorts.

AU - Meyer, Stefanie

AU - Fuchs, Thomas J

AU - Bosserhoff, Anja K

AU - Hofstädter, Ferdinand

AU - Pauer, Armin

AU - Roth, Volker

AU - Buhmann, Joachim M

AU - Moll, Ingrid

AU - Anagnostou, Nikos

AU - Brandner, Johanna

AU - Ikenberg, Kristian

AU - Moch, Holger

AU - Landthaler, Michael

AU - Vogt, Thomas

AU - Wild, Peter J

PY - 2012

Y1 - 2012

N2 - Current staging methods such as tumor thickness, ulceration and invasion of the sentinel node are known to be prognostic parameters in patients with malignant melanoma (MM). However, predictive molecular marker profiles for risk stratification and therapy optimization are not yet available for routine clinical assessment.

AB - Current staging methods such as tumor thickness, ulceration and invasion of the sentinel node are known to be prognostic parameters in patients with malignant melanoma (MM). However, predictive molecular marker profiles for risk stratification and therapy optimization are not yet available for routine clinical assessment.

KW - Adult

KW - Humans

KW - Male

KW - Aged

KW - Female

KW - Middle Aged

KW - Treatment Outcome

KW - Cohort Studies

KW - Prognosis

KW - Proportional Hazards Models

KW - Cells, Cultured

KW - Cell Line, Tumor

KW - Kaplan-Meier Estimate

KW - Tumor Markers, Biological/metabolism

KW - Antigens, CD20/metabolism

KW - Cyclooxygenase 2/metabolism

KW - Immunohistochemistry/statistics & numerical data

KW - Melanoma/metabolism/pathology/therapy

KW - PTEN Phosphohydrolase/metabolism

KW - Purine-Nucleoside Phosphorylase/metabolism

KW - Skin Neoplasms/metabolism/pathology/therapy

KW - Tissue Array Analysis/methods

KW - bcl-2-Associated X Protein/metabolism

KW - bcl-X Protein/metabolism

KW - beta Catenin/metabolism

KW - Adult

KW - Humans

KW - Male

KW - Aged

KW - Female

KW - Middle Aged

KW - Treatment Outcome

KW - Cohort Studies

KW - Prognosis

KW - Proportional Hazards Models

KW - Cells, Cultured

KW - Cell Line, Tumor

KW - Kaplan-Meier Estimate

KW - Tumor Markers, Biological/metabolism

KW - Antigens, CD20/metabolism

KW - Cyclooxygenase 2/metabolism

KW - Immunohistochemistry/statistics & numerical data

KW - Melanoma/metabolism/pathology/therapy

KW - PTEN Phosphohydrolase/metabolism

KW - Purine-Nucleoside Phosphorylase/metabolism

KW - Skin Neoplasms/metabolism/pathology/therapy

KW - Tissue Array Analysis/methods

KW - bcl-2-Associated X Protein/metabolism

KW - bcl-X Protein/metabolism

KW - beta Catenin/metabolism

U2 - 10.1371/journal.pone.0038222

DO - 10.1371/journal.pone.0038222

M3 - SCORING: Journal article

VL - 7

SP - 38222

JO - PLOS ONE

JF - PLOS ONE

SN - 1932-6203

IS - 6

M1 - 6

ER -