A public health perspective on mitigating the global burden of chronic liver disease
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A public health perspective on mitigating the global burden of chronic liver disease. / Balakrishnan, Maya; Rehm, Jürgen.
in: HEPATOLOGY, Jahrgang 79, Nr. 2, 01.02.2024, S. 451-459.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - A public health perspective on mitigating the global burden of chronic liver disease
AU - Balakrishnan, Maya
AU - Rehm, Jürgen
N1 - Copyright © 2023 American Association for the Study of Liver Diseases.
PY - 2024/2/1
Y1 - 2024/2/1
N2 - Chronic liver disease is a significant global health problem. Epidemiological trends do not show improvement in chronic liver disease incidence but rather a shift in etiologies, with steatotic liver disease (SLD) from metabolic dysfunction and alcohol becoming increasingly important causes. Consequently, there is a pressing need to develop a comprehensive public health approach for SLD. To that end, we propose a public health framework for preventing and controlling SLD. The framework is anchored on evidence linking physical inactivity, unhealthy dietary patterns, alcohol use, and obesity with both incidence and progression of SLD. Guided by the framework, we review examples of federal/state-level, community-level, and individual-level interventions with the potential to address these determinants of SLD. Ultimately, mitigating SLD's burden requires primary risk factor reduction at multiple socioecological levels, by scaling up the World Health Organization's "best buys," in addition to developing and implementing SLD-specific control interventions.
AB - Chronic liver disease is a significant global health problem. Epidemiological trends do not show improvement in chronic liver disease incidence but rather a shift in etiologies, with steatotic liver disease (SLD) from metabolic dysfunction and alcohol becoming increasingly important causes. Consequently, there is a pressing need to develop a comprehensive public health approach for SLD. To that end, we propose a public health framework for preventing and controlling SLD. The framework is anchored on evidence linking physical inactivity, unhealthy dietary patterns, alcohol use, and obesity with both incidence and progression of SLD. Guided by the framework, we review examples of federal/state-level, community-level, and individual-level interventions with the potential to address these determinants of SLD. Ultimately, mitigating SLD's burden requires primary risk factor reduction at multiple socioecological levels, by scaling up the World Health Organization's "best buys," in addition to developing and implementing SLD-specific control interventions.
KW - Humans
KW - Public Health
KW - Liver Diseases/epidemiology
KW - Risk Factors
KW - Alcohol Drinking
KW - Obesity
KW - Fatty Liver
KW - Global Health
U2 - 10.1097/HEP.0000000000000679
DO - 10.1097/HEP.0000000000000679
M3 - SCORING: Journal article
C2 - 37943874
VL - 79
SP - 451
EP - 459
JO - HEPATOLOGY
JF - HEPATOLOGY
SN - 0270-9139
IS - 2
ER -