A novel risk-scoring system conducing to chemotherapy decision for patients with pancreatic ductal adenocarcinoma after pancreatectomy
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A novel risk-scoring system conducing to chemotherapy decision for patients with pancreatic ductal adenocarcinoma after pancreatectomy. / Li, Yuqiang; Tian, Mengxiang; Zhou, Yuan; Tan, Fengbo; Liu, Wenxue; Zhao, Lilan; Perez, Daniel; Song, Xiangping; Wang, Dan; Nitschke, Christine; Pei, Qian; Güngör, Cenap.
in: J CANCER, Jahrgang 12, Nr. 14, 2021, S. 4433-4442.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - A novel risk-scoring system conducing to chemotherapy decision for patients with pancreatic ductal adenocarcinoma after pancreatectomy
AU - Li, Yuqiang
AU - Tian, Mengxiang
AU - Zhou, Yuan
AU - Tan, Fengbo
AU - Liu, Wenxue
AU - Zhao, Lilan
AU - Perez, Daniel
AU - Song, Xiangping
AU - Wang, Dan
AU - Nitschke, Christine
AU - Pei, Qian
AU - Güngör, Cenap
N1 - © The author(s).
PY - 2021
Y1 - 2021
N2 - Background: Chemotherapy is suggested to use in all stages of pancreatic cancer. Is it reasonable to recommend chemotherapy for all PDAC patients? It is necessary to distinguish low-risk PDAC patients underwent pancreatectomy, who may not lose survival time due to missed chemotherapy and not need to endure pain, nausea, tiredness, drowsiness, and breath shortness caused by chemotherapy. Methods: Nomograms were constructed with basis from the multivariate Cox regression analysis. X-tile software was utilized to perform risk stratification. Survival curves were used to display the effect of chemotherapy in different risk-stratification. Results: All of the significant variables were used to create the nomograms for overall survival (OS). The total risk score of each patient was calculated by summing the scores related to each variable. X-tile software was utilized to classify patients into high-risk (score >283), median-risk (197
AB - Background: Chemotherapy is suggested to use in all stages of pancreatic cancer. Is it reasonable to recommend chemotherapy for all PDAC patients? It is necessary to distinguish low-risk PDAC patients underwent pancreatectomy, who may not lose survival time due to missed chemotherapy and not need to endure pain, nausea, tiredness, drowsiness, and breath shortness caused by chemotherapy. Methods: Nomograms were constructed with basis from the multivariate Cox regression analysis. X-tile software was utilized to perform risk stratification. Survival curves were used to display the effect of chemotherapy in different risk-stratification. Results: All of the significant variables were used to create the nomograms for overall survival (OS). The total risk score of each patient was calculated by summing the scores related to each variable. X-tile software was utilized to classify patients into high-risk (score >283), median-risk (197
U2 - 10.7150/jca.57768
DO - 10.7150/jca.57768
M3 - SCORING: Journal article
C2 - 34093844
VL - 12
SP - 4433
EP - 4442
JO - J CANCER
JF - J CANCER
SN - 1837-9664
IS - 14
ER -