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A Description of Reference Ranges for Organic Acids in Urine Samples from A Pediatric Population in Iran

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A Description of Reference Ranges for Organic Acids in Urine Samples from A Pediatric Population in Iran. / Keyfi, Fatemeh; Lukacs, Zoltan; Varasteh, Abdolreza.

in: REP BIOCHEM MOL BIOL, Jahrgang 6, Nr. 1, 10.2017, S. 40-50.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Keyfi, F, Lukacs, Z & Varasteh, A 2017, 'A Description of Reference Ranges for Organic Acids in Urine Samples from A Pediatric Population in Iran', REP BIOCHEM MOL BIOL, Jg. 6, Nr. 1, S. 40-50.

APA

Keyfi, F., Lukacs, Z., & Varasteh, A. (2017). A Description of Reference Ranges for Organic Acids in Urine Samples from A Pediatric Population in Iran. REP BIOCHEM MOL BIOL, 6(1), 40-50.

Vancouver

Keyfi F, Lukacs Z, Varasteh A. A Description of Reference Ranges for Organic Acids in Urine Samples from A Pediatric Population in Iran. REP BIOCHEM MOL BIOL. 2017 Okt;6(1):40-50.

Bibtex

@article{1fee8f4652f04fa8af73ba028ea7776b,
title = "A Description of Reference Ranges for Organic Acids in Urine Samples from A Pediatric Population in Iran",
abstract = "BACKGROUND: Organic acids refer to a family of compounds that are intermediates in a variety of metabolic pathways. Many organic acids are present in urine from clinically normal individuals. Elevated levels of urine organic acids cause to the organic acidurias, disorders in which some metabolic pathways in organic acid metabolism are blocked. The present work identified major and minor urinary acidic metabolites in normal subjects, and their quantitative ranges in a pediatric population of Iran.METHODS: Two hundred and fifty-one healthy subjects, including 132 males and 119 females, from 2 days to 15 years of age were enrolled. Urinary organic acids were extracted from urine with organic solvents and identified and quantified by gas chromatography-mass spectrometry.RESULTS: The results provide a foundation on which to check results for patients with potentially abnormal organic acidurias. By this method 98 organic acids were identified in a pediatric population of Iran.CONCLUSION: The present work identifies and quantifies major and minor urinary metabolites excreted by normal subjects. We also analyzed urine from 30 patients with organic acid metabolism abnormalities and compared the concentrations of specific organic acids with those from urines of normal individuals.",
keywords = "Journal Article",
author = "Fatemeh Keyfi and Zoltan Lukacs and Abdolreza Varasteh",
year = "2017",
month = oct,
language = "English",
volume = "6",
pages = "40--50",
journal = "REP BIOCHEM MOL BIOL",
issn = "2322-3480",
publisher = "Varastegan Institute for Medical Sciences",
number = "1",

}

RIS

TY - JOUR

T1 - A Description of Reference Ranges for Organic Acids in Urine Samples from A Pediatric Population in Iran

AU - Keyfi, Fatemeh

AU - Lukacs, Zoltan

AU - Varasteh, Abdolreza

PY - 2017/10

Y1 - 2017/10

N2 - BACKGROUND: Organic acids refer to a family of compounds that are intermediates in a variety of metabolic pathways. Many organic acids are present in urine from clinically normal individuals. Elevated levels of urine organic acids cause to the organic acidurias, disorders in which some metabolic pathways in organic acid metabolism are blocked. The present work identified major and minor urinary acidic metabolites in normal subjects, and their quantitative ranges in a pediatric population of Iran.METHODS: Two hundred and fifty-one healthy subjects, including 132 males and 119 females, from 2 days to 15 years of age were enrolled. Urinary organic acids were extracted from urine with organic solvents and identified and quantified by gas chromatography-mass spectrometry.RESULTS: The results provide a foundation on which to check results for patients with potentially abnormal organic acidurias. By this method 98 organic acids were identified in a pediatric population of Iran.CONCLUSION: The present work identifies and quantifies major and minor urinary metabolites excreted by normal subjects. We also analyzed urine from 30 patients with organic acid metabolism abnormalities and compared the concentrations of specific organic acids with those from urines of normal individuals.

AB - BACKGROUND: Organic acids refer to a family of compounds that are intermediates in a variety of metabolic pathways. Many organic acids are present in urine from clinically normal individuals. Elevated levels of urine organic acids cause to the organic acidurias, disorders in which some metabolic pathways in organic acid metabolism are blocked. The present work identified major and minor urinary acidic metabolites in normal subjects, and their quantitative ranges in a pediatric population of Iran.METHODS: Two hundred and fifty-one healthy subjects, including 132 males and 119 females, from 2 days to 15 years of age were enrolled. Urinary organic acids were extracted from urine with organic solvents and identified and quantified by gas chromatography-mass spectrometry.RESULTS: The results provide a foundation on which to check results for patients with potentially abnormal organic acidurias. By this method 98 organic acids were identified in a pediatric population of Iran.CONCLUSION: The present work identifies and quantifies major and minor urinary metabolites excreted by normal subjects. We also analyzed urine from 30 patients with organic acid metabolism abnormalities and compared the concentrations of specific organic acids with those from urines of normal individuals.

KW - Journal Article

M3 - SCORING: Journal article

C2 - 29090228

VL - 6

SP - 40

EP - 50

JO - REP BIOCHEM MOL BIOL

JF - REP BIOCHEM MOL BIOL

SN - 2322-3480

IS - 1

ER -