73-jährige leber- und nierentransplantierte Patientin mit dumpfen Oberbauchschmerzen und rezidivierendem Nasenbluten

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73-jährige leber- und nierentransplantierte Patientin mit dumpfen Oberbauchschmerzen und rezidivierendem Nasenbluten. / Zinser, M E; Salzer, H J F; Stein, A; von Petersdorff-Campen, Mareike; Koops, A; Holzhüter, J.

in: INTERNIST, Jahrgang 56, Nr. 5, 05.2015, S. 566-72.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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Bibtex

@article{49dee28d402141de806997ea905d003f,
title = "73-j{\"a}hrige leber- und nierentransplantierte Patientin mit dumpfen Oberbauchschmerzen und rezidivierendem Nasenbluten",
abstract = "A 73-year-old female patient who had received a liver and kidney transplantation presented with symptomatic pancytopenia and right-sided upper abdominal pain. The histological investigation of a bone marrow biopsy showed the extremely rare manifestation of a disseminated Merkel cell carcinoma with infiltration of the bone marrow and suppression of hematopoiesis. Also a Coombs test positive hemolytic anemia did not show a significant response to high-dose steroid therapy. Palliative chemotherapy with carboplatin and etoposide at reduced dosage had to be terminated due to deterioration of the patient's general condition. The patient died 2 days after initiation of chemotherapy.",
author = "Zinser, {M E} and Salzer, {H J F} and A Stein and {von Petersdorff-Campen}, Mareike and A Koops and J Holzh{\"u}ter",
year = "2015",
month = may,
doi = "10.1007/s00108-015-3700-5",
language = "Deutsch",
volume = "56",
pages = "566--72",
journal = "INTERNIST",
issn = "0020-9554",
publisher = "Springer",
number = "5",

}

RIS

TY - JOUR

T1 - 73-jährige leber- und nierentransplantierte Patientin mit dumpfen Oberbauchschmerzen und rezidivierendem Nasenbluten

AU - Zinser, M E

AU - Salzer, H J F

AU - Stein, A

AU - von Petersdorff-Campen, Mareike

AU - Koops, A

AU - Holzhüter, J

PY - 2015/5

Y1 - 2015/5

N2 - A 73-year-old female patient who had received a liver and kidney transplantation presented with symptomatic pancytopenia and right-sided upper abdominal pain. The histological investigation of a bone marrow biopsy showed the extremely rare manifestation of a disseminated Merkel cell carcinoma with infiltration of the bone marrow and suppression of hematopoiesis. Also a Coombs test positive hemolytic anemia did not show a significant response to high-dose steroid therapy. Palliative chemotherapy with carboplatin and etoposide at reduced dosage had to be terminated due to deterioration of the patient's general condition. The patient died 2 days after initiation of chemotherapy.

AB - A 73-year-old female patient who had received a liver and kidney transplantation presented with symptomatic pancytopenia and right-sided upper abdominal pain. The histological investigation of a bone marrow biopsy showed the extremely rare manifestation of a disseminated Merkel cell carcinoma with infiltration of the bone marrow and suppression of hematopoiesis. Also a Coombs test positive hemolytic anemia did not show a significant response to high-dose steroid therapy. Palliative chemotherapy with carboplatin and etoposide at reduced dosage had to be terminated due to deterioration of the patient's general condition. The patient died 2 days after initiation of chemotherapy.

U2 - 10.1007/s00108-015-3700-5

DO - 10.1007/s00108-015-3700-5

M3 - SCORING: Zeitschriftenaufsatz

C2 - 25874738

VL - 56

SP - 566

EP - 572

JO - INTERNIST

JF - INTERNIST

SN - 0020-9554

IS - 5

ER -