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5-Year Outcome of Pulmonary Vein Isolation by Loss of Pace Capture on the Ablation Line Versus Electrical Circumferential Pulmonary Vein Isolation

Standard

5-Year Outcome of Pulmonary Vein Isolation by Loss of Pace Capture on the Ablation Line Versus Electrical Circumferential Pulmonary Vein Isolation. / Moser, Julia; Sultan, Arian; Lüker, Jakob; Servatius, Helge; Salzbrunn, Tim; Altenburg, Manuel; Schäffer, Benjamin; Schreiber, Doreen; Akbulak, Ruken Ö; Vogler, Julia; Hoffmann, Boris A; Willems, Stephan; Steven, Daniel.

in: JACC-CLIN ELECTROPHY, Jahrgang 3, Nr. 11, 11.2017, S. 1262-1271.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Moser, J, Sultan, A, Lüker, J, Servatius, H, Salzbrunn, T, Altenburg, M, Schäffer, B, Schreiber, D, Akbulak, RÖ, Vogler, J, Hoffmann, BA, Willems, S & Steven, D 2017, '5-Year Outcome of Pulmonary Vein Isolation by Loss of Pace Capture on the Ablation Line Versus Electrical Circumferential Pulmonary Vein Isolation', JACC-CLIN ELECTROPHY, Jg. 3, Nr. 11, S. 1262-1271. https://doi.org/10.1016/j.jacep.2017.04.019

APA

Moser, J., Sultan, A., Lüker, J., Servatius, H., Salzbrunn, T., Altenburg, M., Schäffer, B., Schreiber, D., Akbulak, R. Ö., Vogler, J., Hoffmann, B. A., Willems, S., & Steven, D. (2017). 5-Year Outcome of Pulmonary Vein Isolation by Loss of Pace Capture on the Ablation Line Versus Electrical Circumferential Pulmonary Vein Isolation. JACC-CLIN ELECTROPHY, 3(11), 1262-1271. https://doi.org/10.1016/j.jacep.2017.04.019

Vancouver

Moser J, Sultan A, Lüker J, Servatius H, Salzbrunn T, Altenburg M et al. 5-Year Outcome of Pulmonary Vein Isolation by Loss of Pace Capture on the Ablation Line Versus Electrical Circumferential Pulmonary Vein Isolation. JACC-CLIN ELECTROPHY. 2017 Nov;3(11):1262-1271. https://doi.org/10.1016/j.jacep.2017.04.019

Bibtex

@article{bdfdeca435694d04af04af9790996e02,
title = "5-Year Outcome of Pulmonary Vein Isolation by Loss of Pace Capture on the Ablation Line Versus Electrical Circumferential Pulmonary Vein Isolation",
abstract = "OBJECTIVES: This study sought to compare long-term arrhythmia-free survival between electrical circumferential pulmonary vein isolation (PVI) and PVI with the endpoint of unexcitability along the ablation line.BACKGROUND: PVI is the standard ablation strategy of paroxysmal atrial fibrillation, although arrhythmia recurrence in long-term follow-up (FU) is high. The endpoint of unexcitability along the ablation line results in decreased arrhythmia recurrence compared to electrical PVI in 1-year FU.METHODS: Seventy-four consecutive patients (age 62.5 ± 10.6 years; 70.3% male) with de novo paroxysmal atrial fibrillation who were initially included in our randomized trial and underwent catheter ablation at our institution were analyzed. Patients who were randomized to either a conventional group (PVI, guided by circumferential catheter signals) or a pace-guided group (PG, anatomical ablation line encircling, ablation until loss of pace capture at 10 V, 2-ms pulse width on the ablation line) underwent long-term FU. The primary endpoint was recurrence of any atrial fibrillation or atrial tachycardia after a blanking period of 3 months.RESULTS: Sixty-nine patients completed a mean FU period of 5.14 ± 0.98 years. Arrhythmia-free survival without antiarrhythmic drug therapy was significantly higher in the PG group (71.05% vs. 25.81%, p = 0.002). Furthermore, multiple procedure success (1.29 ± 0.61 procedures in PG vs. 1.97 ± 1.06 procedures in conventional group, p < 0.001) was higher in the PG group compared to the conventional group (89.47% vs. 58.06%, p = 0.005).CONCLUSIONS: The endpoint of unexcitability along the PVI line improves success rates, resulting in a significant reduction of exposure to invasive procedures in 5-year FU.",
keywords = "Aged, Atrial Fibrillation/physiopathology, Cardiac Pacing, Artificial/methods, Catheter Ablation/instrumentation, Electric Stimulation Therapy/methods, Female, Follow-Up Studies, Humans, Male, Middle Aged, Pulmonary Veins/physiology, Recurrence, Treatment Outcome",
author = "Julia Moser and Arian Sultan and Jakob L{\"u}ker and Helge Servatius and Tim Salzbrunn and Manuel Altenburg and Benjamin Sch{\"a}ffer and Doreen Schreiber and Akbulak, {Ruken {\"O}} and Julia Vogler and Hoffmann, {Boris A} and Stephan Willems and Daniel Steven",
note = "Copyright {\textcopyright} 2017 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.",
year = "2017",
month = nov,
doi = "10.1016/j.jacep.2017.04.019",
language = "English",
volume = "3",
pages = "1262--1271",
journal = "JACC-CLIN ELECTROPHY",
issn = "2405-500X",
publisher = "Elsevier USA",
number = "11",

}

RIS

TY - JOUR

T1 - 5-Year Outcome of Pulmonary Vein Isolation by Loss of Pace Capture on the Ablation Line Versus Electrical Circumferential Pulmonary Vein Isolation

AU - Moser, Julia

AU - Sultan, Arian

AU - Lüker, Jakob

AU - Servatius, Helge

AU - Salzbrunn, Tim

AU - Altenburg, Manuel

AU - Schäffer, Benjamin

AU - Schreiber, Doreen

AU - Akbulak, Ruken Ö

AU - Vogler, Julia

AU - Hoffmann, Boris A

AU - Willems, Stephan

AU - Steven, Daniel

N1 - Copyright © 2017 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

PY - 2017/11

Y1 - 2017/11

N2 - OBJECTIVES: This study sought to compare long-term arrhythmia-free survival between electrical circumferential pulmonary vein isolation (PVI) and PVI with the endpoint of unexcitability along the ablation line.BACKGROUND: PVI is the standard ablation strategy of paroxysmal atrial fibrillation, although arrhythmia recurrence in long-term follow-up (FU) is high. The endpoint of unexcitability along the ablation line results in decreased arrhythmia recurrence compared to electrical PVI in 1-year FU.METHODS: Seventy-four consecutive patients (age 62.5 ± 10.6 years; 70.3% male) with de novo paroxysmal atrial fibrillation who were initially included in our randomized trial and underwent catheter ablation at our institution were analyzed. Patients who were randomized to either a conventional group (PVI, guided by circumferential catheter signals) or a pace-guided group (PG, anatomical ablation line encircling, ablation until loss of pace capture at 10 V, 2-ms pulse width on the ablation line) underwent long-term FU. The primary endpoint was recurrence of any atrial fibrillation or atrial tachycardia after a blanking period of 3 months.RESULTS: Sixty-nine patients completed a mean FU period of 5.14 ± 0.98 years. Arrhythmia-free survival without antiarrhythmic drug therapy was significantly higher in the PG group (71.05% vs. 25.81%, p = 0.002). Furthermore, multiple procedure success (1.29 ± 0.61 procedures in PG vs. 1.97 ± 1.06 procedures in conventional group, p < 0.001) was higher in the PG group compared to the conventional group (89.47% vs. 58.06%, p = 0.005).CONCLUSIONS: The endpoint of unexcitability along the PVI line improves success rates, resulting in a significant reduction of exposure to invasive procedures in 5-year FU.

AB - OBJECTIVES: This study sought to compare long-term arrhythmia-free survival between electrical circumferential pulmonary vein isolation (PVI) and PVI with the endpoint of unexcitability along the ablation line.BACKGROUND: PVI is the standard ablation strategy of paroxysmal atrial fibrillation, although arrhythmia recurrence in long-term follow-up (FU) is high. The endpoint of unexcitability along the ablation line results in decreased arrhythmia recurrence compared to electrical PVI in 1-year FU.METHODS: Seventy-four consecutive patients (age 62.5 ± 10.6 years; 70.3% male) with de novo paroxysmal atrial fibrillation who were initially included in our randomized trial and underwent catheter ablation at our institution were analyzed. Patients who were randomized to either a conventional group (PVI, guided by circumferential catheter signals) or a pace-guided group (PG, anatomical ablation line encircling, ablation until loss of pace capture at 10 V, 2-ms pulse width on the ablation line) underwent long-term FU. The primary endpoint was recurrence of any atrial fibrillation or atrial tachycardia after a blanking period of 3 months.RESULTS: Sixty-nine patients completed a mean FU period of 5.14 ± 0.98 years. Arrhythmia-free survival without antiarrhythmic drug therapy was significantly higher in the PG group (71.05% vs. 25.81%, p = 0.002). Furthermore, multiple procedure success (1.29 ± 0.61 procedures in PG vs. 1.97 ± 1.06 procedures in conventional group, p < 0.001) was higher in the PG group compared to the conventional group (89.47% vs. 58.06%, p = 0.005).CONCLUSIONS: The endpoint of unexcitability along the PVI line improves success rates, resulting in a significant reduction of exposure to invasive procedures in 5-year FU.

KW - Aged

KW - Atrial Fibrillation/physiopathology

KW - Cardiac Pacing, Artificial/methods

KW - Catheter Ablation/instrumentation

KW - Electric Stimulation Therapy/methods

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Male

KW - Middle Aged

KW - Pulmonary Veins/physiology

KW - Recurrence

KW - Treatment Outcome

U2 - 10.1016/j.jacep.2017.04.019

DO - 10.1016/j.jacep.2017.04.019

M3 - SCORING: Journal article

C2 - 29759622

VL - 3

SP - 1262

EP - 1271

JO - JACC-CLIN ELECTROPHY

JF - JACC-CLIN ELECTROPHY

SN - 2405-500X

IS - 11

ER -