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4D flow cardiovascular magnetic resonance for monitoring of aortic valve repair in bicuspid aortic valve disease

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4D flow cardiovascular magnetic resonance for monitoring of aortic valve repair in bicuspid aortic valve disease. / Lenz, Alexander; Petersen, Johannes; Riedel, Christoph; Weinrich, Julius M; Kooijman, Hendrik; Schoennagel, Bjoern P; Adam, Gerhard; Kodolitsch, Yskert; Reichenspurner, Hermann; Girdauskas, Evaldas; Bannas, Peter.

in: J CARDIOVASC MAGN R, Jahrgang 22, Nr. 1, 30.04.2020, S. 29.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Lenz, A, Petersen, J, Riedel, C, Weinrich, JM, Kooijman, H, Schoennagel, BP, Adam, G, Kodolitsch, Y, Reichenspurner, H, Girdauskas, E & Bannas, P 2020, '4D flow cardiovascular magnetic resonance for monitoring of aortic valve repair in bicuspid aortic valve disease', J CARDIOVASC MAGN R, Jg. 22, Nr. 1, S. 29. https://doi.org/10.1186/s12968-020-00608-0

APA

Lenz, A., Petersen, J., Riedel, C., Weinrich, J. M., Kooijman, H., Schoennagel, B. P., Adam, G., Kodolitsch, Y., Reichenspurner, H., Girdauskas, E., & Bannas, P. (2020). 4D flow cardiovascular magnetic resonance for monitoring of aortic valve repair in bicuspid aortic valve disease. J CARDIOVASC MAGN R, 22(1), 29. https://doi.org/10.1186/s12968-020-00608-0

Vancouver

Lenz A, Petersen J, Riedel C, Weinrich JM, Kooijman H, Schoennagel BP et al. 4D flow cardiovascular magnetic resonance for monitoring of aortic valve repair in bicuspid aortic valve disease. J CARDIOVASC MAGN R. 2020 Apr 30;22(1):29. https://doi.org/10.1186/s12968-020-00608-0

Bibtex

@article{3b3fd9b81b7c400a88204cadf4c4ea8a,
title = "4D flow cardiovascular magnetic resonance for monitoring of aortic valve repair in bicuspid aortic valve disease",
abstract = "BACKGROUND: Aortic valve repair has become a treatment option for adults with symptomatic bicuspid (BAV) or unicuspid (UAV) aortic valve insufficiency. Our aim was to demonstrate the feasibility of 4D flow cardiovascular magnetic resonance (CMR) to assess the impact of aortic valve repair on changes in blood flow dynamics in patients with symptomatic BAV or UAV.METHODS: Twenty patients with adult congenital heart disease (median 35 years, range 18-64; 16 male) and symptomatic aortic valve regurgitation (15 BAV, 5 UAV) were prospectively studied. All patients underwent 4D flow CMR before and after aortic valve repair. Aortic valve regurgitant fraction and systolic peak velocity were estimated. The degree of helical and vortical flow was evaluated according to a 3-point scale. Relative flow displacement and wall shear stress (WSS) were quantified at predefined levels in the thoracic aorta.RESULTS: All patients underwent successful aortic valve repair with a significant reduction of aortic valve regurgitation (16.7 ± 9.8% to 6.4 ± 4.4%, p < 0.001) and systolic peak velocity (2.3 ± 0.9 to 1.9 ± 0.4 m/s, p = 0.014). Both helical flow (1.6 ± 0.6 vs. 0.9 ± 0.5, p < 0.001) and vortical flow (1.2 ± 0.8 vs. 0.5 ± 0.6, p = 0.002) as well as both flow displacement (0.3 ± 0.1 vs. 0.25 ± 0.1, p = 0.031) and WSS (0.8 ± 0.2 N/m2 vs. 0.5 ± 0.2 N/m2, p < 0.001) in the ascending aorta were significantly reduced after aortic valve repair.CONCLUSIONS: 4D flow CMR allows assessment of the impact of aortic valve repair on changes in blood flow dynamics in patients with bicuspid aortic valve disease.",
author = "Alexander Lenz and Johannes Petersen and Christoph Riedel and Weinrich, {Julius M} and Hendrik Kooijman and Schoennagel, {Bjoern P} and Gerhard Adam and Yskert Kodolitsch and Hermann Reichenspurner and Evaldas Girdauskas and Peter Bannas",
year = "2020",
month = apr,
day = "30",
doi = "10.1186/s12968-020-00608-0",
language = "English",
volume = "22",
pages = "29",
journal = "J CARDIOVASC MAGN R",
issn = "1097-6647",
publisher = "BioMed Central Ltd.",
number = "1",

}

RIS

TY - JOUR

T1 - 4D flow cardiovascular magnetic resonance for monitoring of aortic valve repair in bicuspid aortic valve disease

AU - Lenz, Alexander

AU - Petersen, Johannes

AU - Riedel, Christoph

AU - Weinrich, Julius M

AU - Kooijman, Hendrik

AU - Schoennagel, Bjoern P

AU - Adam, Gerhard

AU - Kodolitsch, Yskert

AU - Reichenspurner, Hermann

AU - Girdauskas, Evaldas

AU - Bannas, Peter

PY - 2020/4/30

Y1 - 2020/4/30

N2 - BACKGROUND: Aortic valve repair has become a treatment option for adults with symptomatic bicuspid (BAV) or unicuspid (UAV) aortic valve insufficiency. Our aim was to demonstrate the feasibility of 4D flow cardiovascular magnetic resonance (CMR) to assess the impact of aortic valve repair on changes in blood flow dynamics in patients with symptomatic BAV or UAV.METHODS: Twenty patients with adult congenital heart disease (median 35 years, range 18-64; 16 male) and symptomatic aortic valve regurgitation (15 BAV, 5 UAV) were prospectively studied. All patients underwent 4D flow CMR before and after aortic valve repair. Aortic valve regurgitant fraction and systolic peak velocity were estimated. The degree of helical and vortical flow was evaluated according to a 3-point scale. Relative flow displacement and wall shear stress (WSS) were quantified at predefined levels in the thoracic aorta.RESULTS: All patients underwent successful aortic valve repair with a significant reduction of aortic valve regurgitation (16.7 ± 9.8% to 6.4 ± 4.4%, p < 0.001) and systolic peak velocity (2.3 ± 0.9 to 1.9 ± 0.4 m/s, p = 0.014). Both helical flow (1.6 ± 0.6 vs. 0.9 ± 0.5, p < 0.001) and vortical flow (1.2 ± 0.8 vs. 0.5 ± 0.6, p = 0.002) as well as both flow displacement (0.3 ± 0.1 vs. 0.25 ± 0.1, p = 0.031) and WSS (0.8 ± 0.2 N/m2 vs. 0.5 ± 0.2 N/m2, p < 0.001) in the ascending aorta were significantly reduced after aortic valve repair.CONCLUSIONS: 4D flow CMR allows assessment of the impact of aortic valve repair on changes in blood flow dynamics in patients with bicuspid aortic valve disease.

AB - BACKGROUND: Aortic valve repair has become a treatment option for adults with symptomatic bicuspid (BAV) or unicuspid (UAV) aortic valve insufficiency. Our aim was to demonstrate the feasibility of 4D flow cardiovascular magnetic resonance (CMR) to assess the impact of aortic valve repair on changes in blood flow dynamics in patients with symptomatic BAV or UAV.METHODS: Twenty patients with adult congenital heart disease (median 35 years, range 18-64; 16 male) and symptomatic aortic valve regurgitation (15 BAV, 5 UAV) were prospectively studied. All patients underwent 4D flow CMR before and after aortic valve repair. Aortic valve regurgitant fraction and systolic peak velocity were estimated. The degree of helical and vortical flow was evaluated according to a 3-point scale. Relative flow displacement and wall shear stress (WSS) were quantified at predefined levels in the thoracic aorta.RESULTS: All patients underwent successful aortic valve repair with a significant reduction of aortic valve regurgitation (16.7 ± 9.8% to 6.4 ± 4.4%, p < 0.001) and systolic peak velocity (2.3 ± 0.9 to 1.9 ± 0.4 m/s, p = 0.014). Both helical flow (1.6 ± 0.6 vs. 0.9 ± 0.5, p < 0.001) and vortical flow (1.2 ± 0.8 vs. 0.5 ± 0.6, p = 0.002) as well as both flow displacement (0.3 ± 0.1 vs. 0.25 ± 0.1, p = 0.031) and WSS (0.8 ± 0.2 N/m2 vs. 0.5 ± 0.2 N/m2, p < 0.001) in the ascending aorta were significantly reduced after aortic valve repair.CONCLUSIONS: 4D flow CMR allows assessment of the impact of aortic valve repair on changes in blood flow dynamics in patients with bicuspid aortic valve disease.

U2 - 10.1186/s12968-020-00608-0

DO - 10.1186/s12968-020-00608-0

M3 - SCORING: Journal article

C2 - 32354361

VL - 22

SP - 29

JO - J CARDIOVASC MAGN R

JF - J CARDIOVASC MAGN R

SN - 1097-6647

IS - 1

ER -