44-jährige Patientin mit hereditärem nichtpolypösem Kolonkarzinom

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44-jährige Patientin mit hereditärem nichtpolypösem Kolonkarzinom : Vorsorgeuntersuchungen nichtkolonischer Tumoren. / Holzhüter, J; Rösch, T; Block, A; Lohse, A W; Lüth, S.

in: INTERNIST, Jahrgang 54, Nr. 3, 01.03.2013, S. 353-8.

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@article{b94addd9d1ef4d75ada1cd276402d018,
title = "44-j{\"a}hrige Patientin mit heredit{\"a}rem nichtpolyp{\"o}sem Kolonkarzinom: Vorsorgeuntersuchungen nichtkolonischer Tumoren",
abstract = "A 44-year-old woman presented in March 2010 for surveillance esophagogastroduodenoscopy (EGD). In October 2004, rectal cancer had been diagnosed and treated by resection of the rectum with adjuvant chemotherapy. A diagnosis of hereditary nonpolyposis colon carcinoma (HNPCC) was established on the basis of the Amsterdam II criteria. Due to a lack of clear guidelines we decided to perform annual systematic surveillance examinations of the stomach and the most frequent tumor manifestations. Until 2009, extracolonic tumors were not observed in the patient. In March 2010, EGD showed a discrete erosive lesion in the gastric antrum, which was biopsied. Most notably, the histopathological examination revealed a poorly differentiated mucinous adenocarcinoma. Due to the poor differentiation, we decided against technically possible, endoscopic resection. The patient underwent subtotal gastrectomy and is still doing fine 28 months after surgery. This case prompted us to evaluate our surveillance approach in HNPCC patients and to review the literature.",
keywords = "Adult, Colonic Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis, Diagnosis, Differential, Female, Humans, Mass Screening, Stomach Neoplasms",
author = "J Holzh{\"u}ter and T R{\"o}sch and A Block and Lohse, {A W} and S L{\"u}th",
year = "2013",
month = mar,
day = "1",
doi = "10.1007/s00108-012-3224-1",
language = "Deutsch",
volume = "54",
pages = "353--8",
journal = "INTERNIST",
issn = "0020-9554",
publisher = "Springer",
number = "3",

}

RIS

TY - JOUR

T1 - 44-jährige Patientin mit hereditärem nichtpolypösem Kolonkarzinom

T2 - Vorsorgeuntersuchungen nichtkolonischer Tumoren

AU - Holzhüter, J

AU - Rösch, T

AU - Block, A

AU - Lohse, A W

AU - Lüth, S

PY - 2013/3/1

Y1 - 2013/3/1

N2 - A 44-year-old woman presented in March 2010 for surveillance esophagogastroduodenoscopy (EGD). In October 2004, rectal cancer had been diagnosed and treated by resection of the rectum with adjuvant chemotherapy. A diagnosis of hereditary nonpolyposis colon carcinoma (HNPCC) was established on the basis of the Amsterdam II criteria. Due to a lack of clear guidelines we decided to perform annual systematic surveillance examinations of the stomach and the most frequent tumor manifestations. Until 2009, extracolonic tumors were not observed in the patient. In March 2010, EGD showed a discrete erosive lesion in the gastric antrum, which was biopsied. Most notably, the histopathological examination revealed a poorly differentiated mucinous adenocarcinoma. Due to the poor differentiation, we decided against technically possible, endoscopic resection. The patient underwent subtotal gastrectomy and is still doing fine 28 months after surgery. This case prompted us to evaluate our surveillance approach in HNPCC patients and to review the literature.

AB - A 44-year-old woman presented in March 2010 for surveillance esophagogastroduodenoscopy (EGD). In October 2004, rectal cancer had been diagnosed and treated by resection of the rectum with adjuvant chemotherapy. A diagnosis of hereditary nonpolyposis colon carcinoma (HNPCC) was established on the basis of the Amsterdam II criteria. Due to a lack of clear guidelines we decided to perform annual systematic surveillance examinations of the stomach and the most frequent tumor manifestations. Until 2009, extracolonic tumors were not observed in the patient. In March 2010, EGD showed a discrete erosive lesion in the gastric antrum, which was biopsied. Most notably, the histopathological examination revealed a poorly differentiated mucinous adenocarcinoma. Due to the poor differentiation, we decided against technically possible, endoscopic resection. The patient underwent subtotal gastrectomy and is still doing fine 28 months after surgery. This case prompted us to evaluate our surveillance approach in HNPCC patients and to review the literature.

KW - Adult

KW - Colonic Neoplasms

KW - Colorectal Neoplasms, Hereditary Nonpolyposis

KW - Diagnosis, Differential

KW - Female

KW - Humans

KW - Mass Screening

KW - Stomach Neoplasms

U2 - 10.1007/s00108-012-3224-1

DO - 10.1007/s00108-012-3224-1

M3 - SCORING: Zeitschriftenaufsatz

C2 - 23392234

VL - 54

SP - 353

EP - 358

JO - INTERNIST

JF - INTERNIST

SN - 0020-9554

IS - 3

ER -