[28-year old female patient with respiratory insufficiency, elevated liver enzymes, pancytopenia and fever].
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[28-year old female patient with respiratory insufficiency, elevated liver enzymes, pancytopenia and fever]. / Wolschke, Christine; Fiedler, Walter; Habermann, Christian; Janka-Schaub, Gritta; Kluge, Stefan.
in: INTERNIST, Jahrgang 51, Nr. 11, 11, 2010, S. 1434-1438.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - [28-year old female patient with respiratory insufficiency, elevated liver enzymes, pancytopenia and fever].
AU - Wolschke, Christine
AU - Fiedler, Walter
AU - Habermann, Christian
AU - Janka-Schaub, Gritta
AU - Kluge, Stefan
PY - 2010
Y1 - 2010
N2 - We report on a 28-year old female patient with fever and severe respiratory insufficiency requiring mechanical ventilation. Cytomegalovirus pneumonia was diagnosed by bronchoalveolar lavage, and antiviral therapy was initiated. However fever persisted and laboratory workup showed pancytopenia and elevated liver enzymes. Additional blood tests demonstrated a markedly elevated ferritin level and high concentrations of inflammatory cytokines. A diagnosis of hemophagocytic lymphohistiocytosis was made and immunosuppressive therapy was started. The patient's condition and laboratory values improved rapidly.
AB - We report on a 28-year old female patient with fever and severe respiratory insufficiency requiring mechanical ventilation. Cytomegalovirus pneumonia was diagnosed by bronchoalveolar lavage, and antiviral therapy was initiated. However fever persisted and laboratory workup showed pancytopenia and elevated liver enzymes. Additional blood tests demonstrated a markedly elevated ferritin level and high concentrations of inflammatory cytokines. A diagnosis of hemophagocytic lymphohistiocytosis was made and immunosuppressive therapy was started. The patient's condition and laboratory values improved rapidly.
M3 - SCORING: Zeitschriftenaufsatz
VL - 51
SP - 1434
EP - 1438
JO - INTERNIST
JF - INTERNIST
SN - 0020-9554
IS - 11
M1 - 11
ER -