PortalPublikationen19p13.1 is a triple-negative-specific breast cancer suscepti...

19p13.1 is a triple-negative-specific breast cancer susceptibility locus.

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19p13.1 is a triple-negative-specific breast cancer susceptibility locus. / Stevens, Kristen N; Fredericksen, Zachary; Vachon, Celine M; Wang, Xianshu; Margolin, Sara; Lindblom, Annika; Nevanlinna, Heli; Greco, Dario; Aittomäki, Kristiina; Blomqvist, Carl; Chang-Claude, Jenny; Vrieling, Alina; Flesch-Janys, Dieter; Sinn, Hans-Peter; Wang-Gohrke, Shan; Nickels, Stefan; Brauch, Hiltrud; Network, GENICA; Ko, Yon-Dschun; Fischer, Hans-Peter; Schmutzler, Rita K; Meindl, Alfons; Bartram, Claus R; Schott, Sarah; Engel, Christoph; Godwin, Andrew K; Weaver, Joellen; Pathak, Harsh B; Sharma, Priyanka; Brenner, Hermann; Müller, Heiko; Arndt, Volker; Stegmaier, Christa; Miron, Penelope; Yannoukakos, Drakoulis; Stavropoulou, Alexandra; Fountzilas, George; Gogas, Helen J; Swann, Ruth; Dwek, Miriam; Perkins, Annie; Milne, Roger L; Benítez, Javier; Zamora, María Pilar; Pérez, José Ignacio Arias; Bojesen, Stig E; Nielsen, Sune F; Nordestgaard, Børge G; Flyger, Henrik; Guénel, Pascal; Truong, Thérèse; Menegaux, Florence; Cordina-Duverger, Emilie; Burwinkel, Barbara; Marmé, Frederick; Schneeweiss, Andreas; Sohn, Christof; Sawyer, Elinor; Tomlinson, Ian; Kerin, Michael J; Peto, Julian; Johnson, Nichola; Fletcher, Olivia; Isabel, Dos Santos Silva; Fasching, Peter A; Beckmann, Matthias W; Hartmann, Arndt; Ekici, Arif B; Lophatananon, Artitaya; Muir, Kenneth; Puttawibul, Puttisak; Wiangnon, Surapon; Schmidt, Marjanka K; Broeks, Annegien; Braaf, Linde M; Rosenberg, Efraim H; Hopper, John L; Apicella, Carmel; Park, Daniel J; Southey, Melissa C; Swerdlow, Anthony J; Ashworth, Alan; Orr, Nicholas; Schoemaker, Minouk J; Anton-Culver, Hoda; Ziogas, Argyrios; Bernstein, Leslie; Dur, Christina Clarke; Shen, Chen-Yang; Yu, Jyh-Cherng; Hsu, Huan-Ming; Hsiung, Chia-Ni; Hamann, Ute; Dünnebier, Thomas; Rüdiger, Thomas; Ulmer, Hans Ulrich; Pharoah, Paul P; Dunning, Alison M; Humphreys, Manjeet K; Wang, Qin; Cox, Angela; Cross, Simon S; Reed, Malcom W; Hall, Per; Czene, Kamila; Ambrosone, Christine B; Ademuyiwa, Foluso; Hwang, Helena; Eccles, Diana M; Garcia-Closas, Montserrat; Figueroa, Jonine D; Sherman, Mark E; Lissowska, Jolanta; Devilee, Peter; Seynaeve, Caroline; Tollenaar, Rob A E M; Hooning, Maartje J; Andrulis, Irene L; Knight, Julia A; Glendon, Gord; Mulligan, Anna Marie; Winqvist, Robert; Pylkäs, Katri; Jukkola-Vuorinen, Arja; Grip, Mervi; John, Esther M; Miron, Alexander; Alnæs, Grethe Grenaker; Kristensen, Vessela; Børresen-Dale, Anne-Lise; Giles, Graham G; Baglietto, Laura; McLean, Catriona A; Severi, Gianluca; Kosel, Matthew L; Pankratz, V S; Slager, Susan; Olson, Janet E; Radice, Paolo; Peterlongo, Paolo; Manoukian, Siranoush; Barile, Monica; Lambrechts, Diether; Hatse, Sigrid; Dieudonne, Anne-Sophie; Christiaens, Marie-Rose; Chenevix-Trench, Georgia; Group, AOCS; Beesley, Jonathan; Chen, Xiaoqing; Mannermaa, Arto; Kosma, Veli-Matti; Hartikainen, Jaana M; Soini, Ylermi; Easton, Douglas F; Couch, Fergus J.

in: CANCER RES, Jahrgang 72, Nr. 7, 7, 2012, S. 1795-1803.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Stevens, KN, Fredericksen, Z, Vachon, CM, Wang, X, Margolin, S, Lindblom, A, Nevanlinna, H, Greco, D, Aittomäki, K, Blomqvist, C, Chang-Claude, J, Vrieling, A, Flesch-Janys, D, Sinn, H-P, Wang-Gohrke, S, Nickels, S, Brauch, H, Network, GENICA, Ko, Y-D, Fischer, H-P, Schmutzler, RK, Meindl, A, Bartram, CR, Schott, S, Engel, C, Godwin, AK, Weaver, J, Pathak, HB, Sharma, P, Brenner, H, Müller, H, Arndt, V, Stegmaier, C, Miron, P, Yannoukakos, D, Stavropoulou, A, Fountzilas, G, Gogas, HJ, Swann, R, Dwek, M, Perkins, A, Milne, RL, Benítez, J, Zamora, MP, Pérez, JIA, Bojesen, SE, Nielsen, SF, Nordestgaard, BG, Flyger, H, Guénel, P, Truong, T, Menegaux, F, Cordina-Duverger, E, Burwinkel, B, Marmé, F, Schneeweiss, A, Sohn, C, Sawyer, E, Tomlinson, I, Kerin, MJ, Peto, J, Johnson, N, Fletcher, O, Isabel, DSS, Fasching, PA, Beckmann, MW, Hartmann, A, Ekici, AB, Lophatananon, A, Muir, K, Puttawibul, P, Wiangnon, S, Schmidt, MK, Broeks, A, Braaf, LM, Rosenberg, EH, Hopper, JL, Apicella, C, Park, DJ, Southey, MC, Swerdlow, AJ, Ashworth, A, Orr, N, Schoemaker, MJ, Anton-Culver, H, Ziogas, A, Bernstein, L, Dur, CC, Shen, C-Y, Yu, J-C, Hsu, H-M, Hsiung, C-N, Hamann, U, Dünnebier, T, Rüdiger, T, Ulmer, HU, Pharoah, PP, Dunning, AM, Humphreys, MK, Wang, Q, Cox, A, Cross, SS, Reed, MW, Hall, P, Czene, K, Ambrosone, CB, Ademuyiwa, F, Hwang, H, Eccles, DM, Garcia-Closas, M, Figueroa, JD, Sherman, ME, Lissowska, J, Devilee, P, Seynaeve, C, Tollenaar, RAEM, Hooning, MJ, Andrulis, IL, Knight, JA, Glendon, G, Mulligan, AM, Winqvist, R, Pylkäs, K, Jukkola-Vuorinen, A, Grip, M, John, EM, Miron, A, Alnæs, GG, Kristensen, V, Børresen-Dale, A-L, Giles, GG, Baglietto, L, McLean, CA, Severi, G, Kosel, ML, Pankratz, VS, Slager, S, Olson, JE, Radice, P, Peterlongo, P, Manoukian, S, Barile, M, Lambrechts, D, Hatse, S, Dieudonne, A-S, Christiaens, M-R, Chenevix-Trench, G, Group, AOCS, Beesley, J, Chen, X, Mannermaa, A, Kosma, V-M, Hartikainen, JM, Soini, Y, Easton, DF & Couch, FJ 2012, '19p13.1 is a triple-negative-specific breast cancer susceptibility locus.', CANCER RES, Jg. 72, Nr. 7, 7, S. 1795-1803. <http://www.ncbi.nlm.nih.gov/pubmed/22331459?dopt=Citation>

APA

Stevens, K. N., Fredericksen, Z., Vachon, C. M., Wang, X., Margolin, S., Lindblom, A., Nevanlinna, H., Greco, D., Aittomäki, K., Blomqvist, C., Chang-Claude, J., Vrieling, A., Flesch-Janys, D., Sinn, H-P., Wang-Gohrke, S., Nickels, S., Brauch, H., Network, GENICA., Ko, Y-D., ... Couch, F. J. (2012). 19p13.1 is a triple-negative-specific breast cancer susceptibility locus. CANCER RES, 72(7), 1795-1803. [7]. http://www.ncbi.nlm.nih.gov/pubmed/22331459?dopt=Citation

Vancouver

Stevens KN, Fredericksen Z, Vachon CM, Wang X, Margolin S, Lindblom A et al. 19p13.1 is a triple-negative-specific breast cancer susceptibility locus. CANCER RES. 2012;72(7):1795-1803. 7.

Bibtex

@article{fd963c22928b4b4db0d8111c90f1118e,
title = "19p13.1 is a triple-negative-specific breast cancer susceptibility locus.",
abstract = "The 19p13.1 breast cancer susceptibility locus is a modifier of breast cancer risk in BRCA1 mutation carriers and is also associated with the risk of ovarian cancer. Here, we investigated 19p13.1 variation and risk of breast cancer subtypes, defined by estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor-2 (HER2) status, using 48,869 breast cancer cases and 49,787 controls from the Breast Cancer Association Consortium (BCAC). Variants from 19p13.1 were not associated with breast cancer overall or with ER-positive breast cancer but were significantly associated with ER-negative breast cancer risk [rs8170 OR, 1.10; 95% confidence interval (CI), 1.05-1.15; P = 3.49 × 10(-5)] and triple-negative (ER-, PR-, and HER2-negative) breast cancer (rs8170: OR, 1.22; 95% CI, 1.13-1.31; P = 2.22 × 10(-7)). However, rs8170 was no longer associated with ER-negative breast cancer risk when triple-negative cases were excluded (OR, 0.98; 95% CI, 0.89-1.07; P = 0.62). In addition, a combined analysis of triple-negative cases from BCAC and the Triple Negative Breast Cancer Consortium (TNBCC; N = 3,566) identified a genome-wide significant association between rs8170 and triple-negative breast cancer risk (OR, 1.25; 95% CI, 1.18-1.33; P = 3.31 × 10(-13)]. Thus, 19p13.1 is the first triple-negative-specific breast cancer risk locus and the first locus specific to a histologic subtype defined by ER, PR, and HER2 to be identified. These findings provide convincing evidence that genetic susceptibility to breast cancer varies by tumor subtype and that triple-negative tumors and other subtypes likely arise through distinct etiologic pathways.",
keywords = "Humans, Female, Chromosome Mapping, Genetic Loci, Risk, Receptors, Progesterone/analysis, Receptors, Estrogen/*analysis, *Genetic Predisposition to Disease, Breast Neoplasms/chemistry/*genetics, *Chromosomes, Human, Pair 19, Receptor, erbB-2/*analysis, Humans, Female, Chromosome Mapping, Genetic Loci, Risk, Receptors, Progesterone/analysis, Receptors, Estrogen/*analysis, *Genetic Predisposition to Disease, Breast Neoplasms/chemistry/*genetics, *Chromosomes, Human, Pair 19, Receptor, erbB-2/*analysis",
author = "Stevens, {Kristen N} and Zachary Fredericksen and Vachon, {Celine M} and Xianshu Wang and Sara Margolin and Annika Lindblom and Heli Nevanlinna and Dario Greco and Kristiina Aittom{\"a}ki and Carl Blomqvist and Jenny Chang-Claude and Alina Vrieling and Dieter Flesch-Janys and Hans-Peter Sinn and Shan Wang-Gohrke and Stefan Nickels and Hiltrud Brauch and GENICA Network and Yon-Dschun Ko and Hans-Peter Fischer and Schmutzler, {Rita K} and Alfons Meindl and Bartram, {Claus R} and Sarah Schott and Christoph Engel and Godwin, {Andrew K} and Joellen Weaver and Pathak, {Harsh B} and Priyanka Sharma and Hermann Brenner and Heiko M{\"u}ller and Volker Arndt and Christa Stegmaier and Penelope Miron and Drakoulis Yannoukakos and Alexandra Stavropoulou and George Fountzilas and Gogas, {Helen J} and Ruth Swann and Miriam Dwek and Annie Perkins and Milne, {Roger L} and Javier Ben{\'i}tez and Zamora, {Mar{\'i}a Pilar} and P{\'e}rez, {Jos{\'e} Ignacio Arias} and Bojesen, {Stig E} and Nielsen, {Sune F} and Nordestgaard, {B{\o}rge G} and Henrik Flyger and Pascal Gu{\'e}nel and Th{\'e}r{\`e}se Truong and Florence Menegaux and Emilie Cordina-Duverger and Barbara Burwinkel and Frederick Marm{\'e} and Andreas Schneeweiss and Christof Sohn and Elinor Sawyer and Ian Tomlinson and Kerin, {Michael J} and Julian Peto and Nichola Johnson and Olivia Fletcher and Isabel, {Dos Santos Silva} and Fasching, {Peter A} and Beckmann, {Matthias W} and Arndt Hartmann and Ekici, {Arif B} and Artitaya Lophatananon and Kenneth Muir and Puttisak Puttawibul and Surapon Wiangnon and Schmidt, {Marjanka K} and Annegien Broeks and Braaf, {Linde M} and Rosenberg, {Efraim H} and Hopper, {John L} and Carmel Apicella and Park, {Daniel J} and Southey, {Melissa C} and Swerdlow, {Anthony J} and Alan Ashworth and Nicholas Orr and Schoemaker, {Minouk J} and Hoda Anton-Culver and Argyrios Ziogas and Leslie Bernstein and Dur, {Christina Clarke} and Chen-Yang Shen and Jyh-Cherng Yu and Huan-Ming Hsu and Chia-Ni Hsiung and Ute Hamann and Thomas D{\"u}nnebier and Thomas R{\"u}diger and Ulmer, {Hans Ulrich} and Pharoah, {Paul P} and Dunning, {Alison M} and Humphreys, {Manjeet K} and Qin Wang and Angela Cox and Cross, {Simon S} and Reed, {Malcom W} and Per Hall and Kamila Czene and Ambrosone, {Christine B} and Foluso Ademuyiwa and Helena Hwang and Eccles, {Diana M} and Montserrat Garcia-Closas and Figueroa, {Jonine D} and Sherman, {Mark E} and Jolanta Lissowska and Peter Devilee and Caroline Seynaeve and Tollenaar, {Rob A E M} and Hooning, {Maartje J} and Andrulis, {Irene L} and Knight, {Julia A} and Gord Glendon and Mulligan, {Anna Marie} and Robert Winqvist and Katri Pylk{\"a}s and Arja Jukkola-Vuorinen and Mervi Grip and John, {Esther M} and Alexander Miron and Aln{\ae}s, {Grethe Grenaker} and Vessela Kristensen and Anne-Lise B{\o}rresen-Dale and Giles, {Graham G} and Laura Baglietto and McLean, {Catriona A} and Gianluca Severi and Kosel, {Matthew L} and Pankratz, {V S} and Susan Slager and Olson, {Janet E} and Paolo Radice and Paolo Peterlongo and Siranoush Manoukian and Monica Barile and Diether Lambrechts and Sigrid Hatse and Anne-Sophie Dieudonne and Marie-Rose Christiaens and Georgia Chenevix-Trench and AOCS Group and Jonathan Beesley and Xiaoqing Chen and Arto Mannermaa and Veli-Matti Kosma and Hartikainen, {Jaana M} and Ylermi Soini and Easton, {Douglas F} and Couch, {Fergus J}",
year = "2012",
language = "English",
volume = "72",
pages = "1795--1803",
journal = "CANCER RES",
issn = "0008-5472",
publisher = "American Association for Cancer Research Inc.",
number = "7",

}

RIS

TY - JOUR

T1 - 19p13.1 is a triple-negative-specific breast cancer susceptibility locus.

AU - Stevens, Kristen N

AU - Fredericksen, Zachary

AU - Vachon, Celine M

AU - Wang, Xianshu

AU - Margolin, Sara

AU - Lindblom, Annika

AU - Nevanlinna, Heli

AU - Greco, Dario

AU - Aittomäki, Kristiina

AU - Blomqvist, Carl

AU - Chang-Claude, Jenny

AU - Vrieling, Alina

AU - Flesch-Janys, Dieter

AU - Sinn, Hans-Peter

AU - Wang-Gohrke, Shan

AU - Nickels, Stefan

AU - Brauch, Hiltrud

AU - Network, GENICA

AU - Ko, Yon-Dschun

AU - Fischer, Hans-Peter

AU - Schmutzler, Rita K

AU - Meindl, Alfons

AU - Bartram, Claus R

AU - Schott, Sarah

AU - Engel, Christoph

AU - Godwin, Andrew K

AU - Weaver, Joellen

AU - Pathak, Harsh B

AU - Sharma, Priyanka

AU - Brenner, Hermann

AU - Müller, Heiko

AU - Arndt, Volker

AU - Stegmaier, Christa

AU - Miron, Penelope

AU - Yannoukakos, Drakoulis

AU - Stavropoulou, Alexandra

AU - Fountzilas, George

AU - Gogas, Helen J

AU - Swann, Ruth

AU - Dwek, Miriam

AU - Perkins, Annie

AU - Milne, Roger L

AU - Benítez, Javier

AU - Zamora, María Pilar

AU - Pérez, José Ignacio Arias

AU - Bojesen, Stig E

AU - Nielsen, Sune F

AU - Nordestgaard, Børge G

AU - Flyger, Henrik

AU - Guénel, Pascal

AU - Truong, Thérèse

AU - Menegaux, Florence

AU - Cordina-Duverger, Emilie

AU - Burwinkel, Barbara

AU - Marmé, Frederick

AU - Schneeweiss, Andreas

AU - Sohn, Christof

AU - Sawyer, Elinor

AU - Tomlinson, Ian

AU - Kerin, Michael J

AU - Peto, Julian

AU - Johnson, Nichola

AU - Fletcher, Olivia

AU - Isabel, Dos Santos Silva

AU - Fasching, Peter A

AU - Beckmann, Matthias W

AU - Hartmann, Arndt

AU - Ekici, Arif B

AU - Lophatananon, Artitaya

AU - Muir, Kenneth

AU - Puttawibul, Puttisak

AU - Wiangnon, Surapon

AU - Schmidt, Marjanka K

AU - Broeks, Annegien

AU - Braaf, Linde M

AU - Rosenberg, Efraim H

AU - Hopper, John L

AU - Apicella, Carmel

AU - Park, Daniel J

AU - Southey, Melissa C

AU - Swerdlow, Anthony J

AU - Ashworth, Alan

AU - Orr, Nicholas

AU - Schoemaker, Minouk J

AU - Anton-Culver, Hoda

AU - Ziogas, Argyrios

AU - Bernstein, Leslie

AU - Dur, Christina Clarke

AU - Shen, Chen-Yang

AU - Yu, Jyh-Cherng

AU - Hsu, Huan-Ming

AU - Hsiung, Chia-Ni

AU - Hamann, Ute

AU - Dünnebier, Thomas

AU - Rüdiger, Thomas

AU - Ulmer, Hans Ulrich

AU - Pharoah, Paul P

AU - Dunning, Alison M

AU - Humphreys, Manjeet K

AU - Wang, Qin

AU - Cox, Angela

AU - Cross, Simon S

AU - Reed, Malcom W

AU - Hall, Per

AU - Czene, Kamila

AU - Ambrosone, Christine B

AU - Ademuyiwa, Foluso

AU - Hwang, Helena

AU - Eccles, Diana M

AU - Garcia-Closas, Montserrat

AU - Figueroa, Jonine D

AU - Sherman, Mark E

AU - Lissowska, Jolanta

AU - Devilee, Peter

AU - Seynaeve, Caroline

AU - Tollenaar, Rob A E M

AU - Hooning, Maartje J

AU - Andrulis, Irene L

AU - Knight, Julia A

AU - Glendon, Gord

AU - Mulligan, Anna Marie

AU - Winqvist, Robert

AU - Pylkäs, Katri

AU - Jukkola-Vuorinen, Arja

AU - Grip, Mervi

AU - John, Esther M

AU - Miron, Alexander

AU - Alnæs, Grethe Grenaker

AU - Kristensen, Vessela

AU - Børresen-Dale, Anne-Lise

AU - Giles, Graham G

AU - Baglietto, Laura

AU - McLean, Catriona A

AU - Severi, Gianluca

AU - Kosel, Matthew L

AU - Pankratz, V S

AU - Slager, Susan

AU - Olson, Janet E

AU - Radice, Paolo

AU - Peterlongo, Paolo

AU - Manoukian, Siranoush

AU - Barile, Monica

AU - Lambrechts, Diether

AU - Hatse, Sigrid

AU - Dieudonne, Anne-Sophie

AU - Christiaens, Marie-Rose

AU - Chenevix-Trench, Georgia

AU - Group, AOCS

AU - Beesley, Jonathan

AU - Chen, Xiaoqing

AU - Mannermaa, Arto

AU - Kosma, Veli-Matti

AU - Hartikainen, Jaana M

AU - Soini, Ylermi

AU - Easton, Douglas F

AU - Couch, Fergus J

PY - 2012

Y1 - 2012

N2 - The 19p13.1 breast cancer susceptibility locus is a modifier of breast cancer risk in BRCA1 mutation carriers and is also associated with the risk of ovarian cancer. Here, we investigated 19p13.1 variation and risk of breast cancer subtypes, defined by estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor-2 (HER2) status, using 48,869 breast cancer cases and 49,787 controls from the Breast Cancer Association Consortium (BCAC). Variants from 19p13.1 were not associated with breast cancer overall or with ER-positive breast cancer but were significantly associated with ER-negative breast cancer risk [rs8170 OR, 1.10; 95% confidence interval (CI), 1.05-1.15; P = 3.49 × 10(-5)] and triple-negative (ER-, PR-, and HER2-negative) breast cancer (rs8170: OR, 1.22; 95% CI, 1.13-1.31; P = 2.22 × 10(-7)). However, rs8170 was no longer associated with ER-negative breast cancer risk when triple-negative cases were excluded (OR, 0.98; 95% CI, 0.89-1.07; P = 0.62). In addition, a combined analysis of triple-negative cases from BCAC and the Triple Negative Breast Cancer Consortium (TNBCC; N = 3,566) identified a genome-wide significant association between rs8170 and triple-negative breast cancer risk (OR, 1.25; 95% CI, 1.18-1.33; P = 3.31 × 10(-13)]. Thus, 19p13.1 is the first triple-negative-specific breast cancer risk locus and the first locus specific to a histologic subtype defined by ER, PR, and HER2 to be identified. These findings provide convincing evidence that genetic susceptibility to breast cancer varies by tumor subtype and that triple-negative tumors and other subtypes likely arise through distinct etiologic pathways.

AB - The 19p13.1 breast cancer susceptibility locus is a modifier of breast cancer risk in BRCA1 mutation carriers and is also associated with the risk of ovarian cancer. Here, we investigated 19p13.1 variation and risk of breast cancer subtypes, defined by estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor-2 (HER2) status, using 48,869 breast cancer cases and 49,787 controls from the Breast Cancer Association Consortium (BCAC). Variants from 19p13.1 were not associated with breast cancer overall or with ER-positive breast cancer but were significantly associated with ER-negative breast cancer risk [rs8170 OR, 1.10; 95% confidence interval (CI), 1.05-1.15; P = 3.49 × 10(-5)] and triple-negative (ER-, PR-, and HER2-negative) breast cancer (rs8170: OR, 1.22; 95% CI, 1.13-1.31; P = 2.22 × 10(-7)). However, rs8170 was no longer associated with ER-negative breast cancer risk when triple-negative cases were excluded (OR, 0.98; 95% CI, 0.89-1.07; P = 0.62). In addition, a combined analysis of triple-negative cases from BCAC and the Triple Negative Breast Cancer Consortium (TNBCC; N = 3,566) identified a genome-wide significant association between rs8170 and triple-negative breast cancer risk (OR, 1.25; 95% CI, 1.18-1.33; P = 3.31 × 10(-13)]. Thus, 19p13.1 is the first triple-negative-specific breast cancer risk locus and the first locus specific to a histologic subtype defined by ER, PR, and HER2 to be identified. These findings provide convincing evidence that genetic susceptibility to breast cancer varies by tumor subtype and that triple-negative tumors and other subtypes likely arise through distinct etiologic pathways.

KW - Humans

KW - Female

KW - Chromosome Mapping

KW - Genetic Loci

KW - Risk

KW - Receptors, Progesterone/analysis

KW - Receptors, Estrogen/analysis

KW - Genetic Predisposition to Disease

KW - Breast Neoplasms/chemistry/genetics

KW - Chromosomes, Human, Pair 19

KW - Receptor, erbB-2/analysis

KW - Humans

KW - Female

KW - Chromosome Mapping

KW - Genetic Loci

KW - Risk

KW - Receptors, Progesterone/analysis

KW - Receptors, Estrogen/analysis

KW - Genetic Predisposition to Disease

KW - Breast Neoplasms/chemistry/genetics

KW - Chromosomes, Human, Pair 19

KW - Receptor, erbB-2/analysis

M3 - SCORING: Journal article

VL - 72

SP - 1795

EP - 1803

JO - CANCER RES

JF - CANCER RES

SN - 0008-5472

IS - 7

M1 - 7

ER -