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УНИВЕРСАЛЬНАЯ МОДУЛЬНАЯ СИСТЕМА СКРИНИНГА IN VITRO ПОТЕНЦИАЛЬНЫХ ИНГИБИТОРОВ РЕПЛИКАЦИИ ВИЧ-1

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УНИВЕРСАЛЬНАЯ МОДУЛЬНАЯ СИСТЕМА СКРИНИНГА IN VITRO ПОТЕНЦИАЛЬНЫХ ИНГИБИТОРОВ РЕПЛИКАЦИИ ВИЧ-1. / Prokof'eva, M M; Orlova, N N; Gornostaeva, A S; Shul'gin, A A; Nikitenko, N A; Senchenko, V N; Lebedev, T D; Spirin, P V; Riecken, Kristoffer; Fehse, B; Stocking, C; Prasolov, V S.

in: MOL BIOL (MOSK), Jahrgang 48, Nr. 2, 09.04.2015, S. 344-8.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Prokof'eva, MM, Orlova, NN, Gornostaeva, AS, Shul'gin, AA, Nikitenko, NA, Senchenko, VN, Lebedev, TD, Spirin, PV, Riecken, K, Fehse, B, Stocking, C & Prasolov, VS 2015, 'УНИВЕРСАЛЬНАЯ МОДУЛЬНАЯ СИСТЕМА СКРИНИНГА IN VITRO ПОТЕНЦИАЛЬНЫХ ИНГИБИТОРОВ РЕПЛИКАЦИИ ВИЧ-1', MOL BIOL (MOSK), Jg. 48, Nr. 2, S. 344-8.

APA

Prokof'eva, M. M., Orlova, N. N., Gornostaeva, A. S., Shul'gin, A. A., Nikitenko, N. A., Senchenko, V. N., Lebedev, T. D., Spirin, P. V., Riecken, K., Fehse, B., Stocking, C., & Prasolov, V. S. (2015). УНИВЕРСАЛЬНАЯ МОДУЛЬНАЯ СИСТЕМА СКРИНИНГА IN VITRO ПОТЕНЦИАЛЬНЫХ ИНГИБИТОРОВ РЕПЛИКАЦИИ ВИЧ-1. MOL BIOL (MOSK), 48(2), 344-8.

Vancouver

Prokof'eva MM, Orlova NN, Gornostaeva AS, Shul'gin AA, Nikitenko NA, Senchenko VN et al. УНИВЕРСАЛЬНАЯ МОДУЛЬНАЯ СИСТЕМА СКРИНИНГА IN VITRO ПОТЕНЦИАЛЬНЫХ ИНГИБИТОРОВ РЕПЛИКАЦИИ ВИЧ-1. MOL BIOL (MOSK). 2015 Apr 9;48(2):344-8.

Bibtex

@article{1f25037c913a4d82814a04fcf8700532,
title = "УНИВЕРСАЛЬНАЯ МОДУЛЬНАЯ СИСТЕМА СКРИНИНГА IN VITRO ПОТЕНЦИАЛЬНЫХ ИНГИБИТОРОВ РЕПЛИКАЦИИ ВИЧ-1",
abstract = "Here we describe a system based on recombinant lentiviral vectors for the safe screening of potential anti-HIV drugs. The system allows to evaluate the sensitivity of HIVl-1 reverse transcriptase and integrase (wild-type as well as mutant forms of these enzymes detected in drug-resistant virus isolates) towards different drugs and substances, but also to screen inhibitors of other stages of HIV-1 life cycle.",
keywords = "Anti-HIV Agents, Drug Resistance, Viral, Flow Cytometry, Gene Expression, Genes, Reporter, Genetic Vectors, Green Fluorescent Proteins, HEK293 Cells, HIV Integrase, HIV Integrase Inhibitors, HIV Reverse Transcriptase, HIV-1, High-Throughput Screening Assays, Humans, Lentivirus, Transduction, Genetic, Virion, Virus Replication",
author = "Prokof'eva, {M M} and Orlova, {N N} and Gornostaeva, {A S} and Shul'gin, {A A} and Nikitenko, {N A} and Senchenko, {V N} and Lebedev, {T D} and Spirin, {P V} and Kristoffer Riecken and B Fehse and C Stocking and Prasolov, {V S}",
year = "2015",
month = apr,
day = "9",
language = "Russisch",
volume = "48",
pages = "344--8",
journal = "MOL BIOL (MOSK)",
issn = "0026-8984",
publisher = "Russian Academy of Sciences",
number = "2",

}

RIS

TY - JOUR

T1 - УНИВЕРСАЛЬНАЯ МОДУЛЬНАЯ СИСТЕМА СКРИНИНГА IN VITRO ПОТЕНЦИАЛЬНЫХ ИНГИБИТОРОВ РЕПЛИКАЦИИ ВИЧ-1

AU - Prokof'eva, M M

AU - Orlova, N N

AU - Gornostaeva, A S

AU - Shul'gin, A A

AU - Nikitenko, N A

AU - Senchenko, V N

AU - Lebedev, T D

AU - Spirin, P V

AU - Riecken, Kristoffer

AU - Fehse, B

AU - Stocking, C

AU - Prasolov, V S

PY - 2015/4/9

Y1 - 2015/4/9

N2 - Here we describe a system based on recombinant lentiviral vectors for the safe screening of potential anti-HIV drugs. The system allows to evaluate the sensitivity of HIVl-1 reverse transcriptase and integrase (wild-type as well as mutant forms of these enzymes detected in drug-resistant virus isolates) towards different drugs and substances, but also to screen inhibitors of other stages of HIV-1 life cycle.

AB - Here we describe a system based on recombinant lentiviral vectors for the safe screening of potential anti-HIV drugs. The system allows to evaluate the sensitivity of HIVl-1 reverse transcriptase and integrase (wild-type as well as mutant forms of these enzymes detected in drug-resistant virus isolates) towards different drugs and substances, but also to screen inhibitors of other stages of HIV-1 life cycle.

KW - Anti-HIV Agents

KW - Drug Resistance, Viral

KW - Flow Cytometry

KW - Gene Expression

KW - Genes, Reporter

KW - Genetic Vectors

KW - Green Fluorescent Proteins

KW - HEK293 Cells

KW - HIV Integrase

KW - HIV Integrase Inhibitors

KW - HIV Reverse Transcriptase

KW - HIV-1

KW - High-Throughput Screening Assays

KW - Humans

KW - Lentivirus

KW - Transduction, Genetic

KW - Virion

KW - Virus Replication

M3 - SCORING: Zeitschriftenaufsatz

C2 - 25850304

VL - 48

SP - 344

EP - 348

JO - MOL BIOL (MOSK)

JF - MOL BIOL (MOSK)

SN - 0026-8984

IS - 2

ER -