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Use of an implantable loop recorder to increase the diagnostic yield in unexplained syncope: results from the PICTURE registry

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Use of an implantable loop recorder to increase the diagnostic yield in unexplained syncope: results from the PICTURE registry. / Edvardsson, Nils; Frykman, Viveka; van Mechelen, Rob; Mitro, Peter; Mohii-Oskarsson, Afsaneh; Pasquié, Jean-Luc; Ramanna, Hemanth; Schwertfeger, Frank; Ventura, Rodolfo; Voulgaraki, Despina; Garutti, Claudio; Stolt, Pelle; Linker, Nicholas J; PICTURE Study Group.

In: EUROPACE, Vol. 13, No. 2, 02.2011, p. 262-269.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Edvardsson, N, Frykman, V, van Mechelen, R, Mitro, P, Mohii-Oskarsson, A, Pasquié, J-L, Ramanna, H, Schwertfeger, F, Ventura, R, Voulgaraki, D, Garutti, C, Stolt, P, Linker, NJ & PICTURE Study Group 2011, 'Use of an implantable loop recorder to increase the diagnostic yield in unexplained syncope: results from the PICTURE registry', EUROPACE, vol. 13, no. 2, pp. 262-269. https://doi.org/10.1093/europace/euq418

APA

Edvardsson, N., Frykman, V., van Mechelen, R., Mitro, P., Mohii-Oskarsson, A., Pasquié, J-L., Ramanna, H., Schwertfeger, F., Ventura, R., Voulgaraki, D., Garutti, C., Stolt, P., Linker, N. J., & PICTURE Study Group (2011). Use of an implantable loop recorder to increase the diagnostic yield in unexplained syncope: results from the PICTURE registry. EUROPACE, 13(2), 262-269. https://doi.org/10.1093/europace/euq418

Vancouver

Edvardsson N, Frykman V, van Mechelen R, Mitro P, Mohii-Oskarsson A, Pasquié J-L et al. Use of an implantable loop recorder to increase the diagnostic yield in unexplained syncope: results from the PICTURE registry. EUROPACE. 2011 Feb;13(2):262-269. https://doi.org/10.1093/europace/euq418

Bibtex

@article{f712f480dede43c78ae0393d6b346d41,
title = "Use of an implantable loop recorder to increase the diagnostic yield in unexplained syncope: results from the PICTURE registry",
abstract = "AIMS: To collect information on the use of the Reveal implantable loop recorder (ILR) in the patient care pathway and to investigate its effectiveness in the diagnosis of unexplained recurrent syncope in everyday clinical practice.METHODS AND RESULTS: Prospective, multicentre, observational study conducted in 2006-2009 in 10 European countries and Israel. Eligible patients had recurrent unexplained syncope or pre-syncope. Subjects received a Reveal Plus, DX or XT. Follow up was until the first recurrence of a syncopal event leading to a diagnosis or for ≥1 year. In the course of the study, patients were evaluated by an average of three different specialists for management of their syncope and underwent a median of 13 tests (range 9-20). Significant physical trauma had been experienced in association with a syncopal episode by 36% of patients. Average follow-up time after ILR implant was 10±6 months. Follow-up visit data were available for 570 subjects. The percentages of patients with recurrence of syncope were 19, 26, and 36% after 3, 6, and 12 months, respectively. Of 218 events within the study, ILR-guided diagnosis was obtained in 170 cases (78%), of which 128 (75%) were cardiac.CONCLUSION: A large number of diagnostic tests were undertaken in patients with unexplained syncope without providing conclusive data. In contrast, the ILR revealed or contributed to establishing the mechanism of syncope in the vast majority of patients. The findings support the recommendation in current guidelines that an ILR should be implanted early rather than late in the evaluation of unexplained syncope.",
keywords = "Adult, Aged, Arrhythmias, Cardiac/complications, Diagnostic Tests, Routine, Electrocardiography, Ambulatory/instrumentation, Electrodes, Implanted, Europe, Female, Follow-Up Studies, Humans, Israel, Male, Middle Aged, Monitoring, Physiologic/instrumentation, Practice Guidelines as Topic, Prospective Studies, Recurrence, Registries, Retrospective Studies, Syncope/epidemiology",
author = "Nils Edvardsson and Viveka Frykman and {van Mechelen}, Rob and Peter Mitro and Afsaneh Mohii-Oskarsson and Jean-Luc Pasqui{\'e} and Hemanth Ramanna and Frank Schwertfeger and Rodolfo Ventura and Despina Voulgaraki and Claudio Garutti and Pelle Stolt and Linker, {Nicholas J} and {PICTURE Study Group}",
year = "2011",
month = feb,
doi = "10.1093/europace/euq418",
language = "English",
volume = "13",
pages = "262--269",
journal = "EUROPACE",
issn = "1099-5129",
publisher = "Oxford University Press",
number = "2",

}

RIS

TY - JOUR

T1 - Use of an implantable loop recorder to increase the diagnostic yield in unexplained syncope: results from the PICTURE registry

AU - Edvardsson, Nils

AU - Frykman, Viveka

AU - van Mechelen, Rob

AU - Mitro, Peter

AU - Mohii-Oskarsson, Afsaneh

AU - Pasquié, Jean-Luc

AU - Ramanna, Hemanth

AU - Schwertfeger, Frank

AU - Ventura, Rodolfo

AU - Voulgaraki, Despina

AU - Garutti, Claudio

AU - Stolt, Pelle

AU - Linker, Nicholas J

AU - PICTURE Study Group

PY - 2011/2

Y1 - 2011/2

N2 - AIMS: To collect information on the use of the Reveal implantable loop recorder (ILR) in the patient care pathway and to investigate its effectiveness in the diagnosis of unexplained recurrent syncope in everyday clinical practice.METHODS AND RESULTS: Prospective, multicentre, observational study conducted in 2006-2009 in 10 European countries and Israel. Eligible patients had recurrent unexplained syncope or pre-syncope. Subjects received a Reveal Plus, DX or XT. Follow up was until the first recurrence of a syncopal event leading to a diagnosis or for ≥1 year. In the course of the study, patients were evaluated by an average of three different specialists for management of their syncope and underwent a median of 13 tests (range 9-20). Significant physical trauma had been experienced in association with a syncopal episode by 36% of patients. Average follow-up time after ILR implant was 10±6 months. Follow-up visit data were available for 570 subjects. The percentages of patients with recurrence of syncope were 19, 26, and 36% after 3, 6, and 12 months, respectively. Of 218 events within the study, ILR-guided diagnosis was obtained in 170 cases (78%), of which 128 (75%) were cardiac.CONCLUSION: A large number of diagnostic tests were undertaken in patients with unexplained syncope without providing conclusive data. In contrast, the ILR revealed or contributed to establishing the mechanism of syncope in the vast majority of patients. The findings support the recommendation in current guidelines that an ILR should be implanted early rather than late in the evaluation of unexplained syncope.

AB - AIMS: To collect information on the use of the Reveal implantable loop recorder (ILR) in the patient care pathway and to investigate its effectiveness in the diagnosis of unexplained recurrent syncope in everyday clinical practice.METHODS AND RESULTS: Prospective, multicentre, observational study conducted in 2006-2009 in 10 European countries and Israel. Eligible patients had recurrent unexplained syncope or pre-syncope. Subjects received a Reveal Plus, DX or XT. Follow up was until the first recurrence of a syncopal event leading to a diagnosis or for ≥1 year. In the course of the study, patients were evaluated by an average of three different specialists for management of their syncope and underwent a median of 13 tests (range 9-20). Significant physical trauma had been experienced in association with a syncopal episode by 36% of patients. Average follow-up time after ILR implant was 10±6 months. Follow-up visit data were available for 570 subjects. The percentages of patients with recurrence of syncope were 19, 26, and 36% after 3, 6, and 12 months, respectively. Of 218 events within the study, ILR-guided diagnosis was obtained in 170 cases (78%), of which 128 (75%) were cardiac.CONCLUSION: A large number of diagnostic tests were undertaken in patients with unexplained syncope without providing conclusive data. In contrast, the ILR revealed or contributed to establishing the mechanism of syncope in the vast majority of patients. The findings support the recommendation in current guidelines that an ILR should be implanted early rather than late in the evaluation of unexplained syncope.

KW - Adult

KW - Aged

KW - Arrhythmias, Cardiac/complications

KW - Diagnostic Tests, Routine

KW - Electrocardiography, Ambulatory/instrumentation

KW - Electrodes, Implanted

KW - Europe

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Israel

KW - Male

KW - Middle Aged

KW - Monitoring, Physiologic/instrumentation

KW - Practice Guidelines as Topic

KW - Prospective Studies

KW - Recurrence

KW - Registries

KW - Retrospective Studies

KW - Syncope/epidemiology

U2 - 10.1093/europace/euq418

DO - 10.1093/europace/euq418

M3 - SCORING: Journal article

C2 - 21097478

VL - 13

SP - 262

EP - 269

JO - EUROPACE

JF - EUROPACE

SN - 1099-5129

IS - 2

ER -