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Ultrasound-based "CEUS-Bosniak"classification for cystic renal lesions: an 8-year clinical experience

Standard

Ultrasound-based "CEUS-Bosniak"classification for cystic renal lesions: an 8-year clinical experience. / Herms, Elena; Weirich, Gregor; Maurer, Tobias; Wagenpfeil, Stefan; Preuss, Stephanie; Sauter, Andreas; Heck, Matthias; Gärtner, Anita; Hauner, Katharina; Autenrieth, Michael; Kübler, Hubert P; Holzapfel, Konstantin; Schwarz-Boeger, Ulrike; Heemann, Uwe; Slotta-Huspenina, Julia; Stock, Konrad Friedrich.

In: WORLD J UROL, Vol. 41, No. 3, 03.2023, p. 679-685.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Herms, E, Weirich, G, Maurer, T, Wagenpfeil, S, Preuss, S, Sauter, A, Heck, M, Gärtner, A, Hauner, K, Autenrieth, M, Kübler, HP, Holzapfel, K, Schwarz-Boeger, U, Heemann, U, Slotta-Huspenina, J & Stock, KF 2023, 'Ultrasound-based "CEUS-Bosniak"classification for cystic renal lesions: an 8-year clinical experience', WORLD J UROL, vol. 41, no. 3, pp. 679-685. https://doi.org/10.1007/s00345-022-04094-0

APA

Herms, E., Weirich, G., Maurer, T., Wagenpfeil, S., Preuss, S., Sauter, A., Heck, M., Gärtner, A., Hauner, K., Autenrieth, M., Kübler, H. P., Holzapfel, K., Schwarz-Boeger, U., Heemann, U., Slotta-Huspenina, J., & Stock, K. F. (2023). Ultrasound-based "CEUS-Bosniak"classification for cystic renal lesions: an 8-year clinical experience. WORLD J UROL, 41(3), 679-685. https://doi.org/10.1007/s00345-022-04094-0

Vancouver

Herms E, Weirich G, Maurer T, Wagenpfeil S, Preuss S, Sauter A et al. Ultrasound-based "CEUS-Bosniak"classification for cystic renal lesions: an 8-year clinical experience. WORLD J UROL. 2023 Mar;41(3):679-685. https://doi.org/10.1007/s00345-022-04094-0

Bibtex

@article{14e513b7f49245798ec11d885ede2c57,
title = "Ultrasound-based {"}CEUS-Bosniak{"}classification for cystic renal lesions: an 8-year clinical experience",
abstract = "PURPOSE: Renal cysts comprise benign and malignant entities. Risk assessment profits from CT/MRI imaging using the Bosniak classification. While Bosniak-IIF, -III, and -IV cover complex cyst variants, Bosniak-IIF and -III stand out due to notorious overestimation. Contrast-enhanced ultrasound (CEUS) is promising to overcome this deficit but warrants standardization. This study addresses the benefits of a combined CEUS and CT/MRI evaluation of renal cysts. The study provides a realistic account of kidney tumor boards' intricacies in trying to validate renal cysts.METHODS: 247 patients were examined over 8 years. CEUS lesions were graded according to CEUS-Bosniak (IIF, III, IV). 55 lesions were resected, CEUS-Bosniak- and CT/MRI-Bosniak-classification were correlated with histopathological diagnosis. Interobserver agreement between the classifications was evaluated statistically. 105 lesions were followed by ultrasound, and change in CEUS-Bosniak-types and lesion size were documented.RESULTS: 146 patients (156 lesions) were included. CEUS classified 67 lesions as CEUS-Bosniak-IIF, 44 as CEUS-Bosniak-III, and 45 as CEUS-Bosniak-IV. Histopathology of 55 resected lesions revealed benign cysts in all CEUS-Bosniak-IIF lesions (2/2), 40% of CEUS-Bosniak-III and 8% of CEUS-Bosniak-IV, whereas malignancy was uncovered in 60% of CEUS-Bosniak-III and 92% of CEUS-Bosniak-IV. Overall, CEUS-Bosniak-types matched CT/MRI-Bosniak types in 58% (fair agreement, κ = 0.28). CEUS-Bosniak resulted in higher stages than CT/MRI-Bosniak (40%). Ultrasound follow-up of 105 lesions detected no relevant differences between CEUS-Bosniak-types concerning cysts size. 99% of lesions showed the same CEUS-Bosniak-type.CONCLUSION: The CEUS-Bosniak classification is an essential tool in clinical practice to differentiate and monitor renal cystic lesions and empowers diagnostic work-up and patient care.",
author = "Elena Herms and Gregor Weirich and Tobias Maurer and Stefan Wagenpfeil and Stephanie Preuss and Andreas Sauter and Matthias Heck and Anita G{\"a}rtner and Katharina Hauner and Michael Autenrieth and K{\"u}bler, {Hubert P} and Konstantin Holzapfel and Ulrike Schwarz-Boeger and Uwe Heemann and Julia Slotta-Huspenina and Stock, {Konrad Friedrich}",
note = "{\textcopyright} 2022. The Author(s).",
year = "2023",
month = mar,
doi = "10.1007/s00345-022-04094-0",
language = "English",
volume = "41",
pages = "679--685",
journal = "WORLD J UROL",
issn = "0724-4983",
publisher = "Springer",
number = "3",

}

RIS

TY - JOUR

T1 - Ultrasound-based "CEUS-Bosniak"classification for cystic renal lesions: an 8-year clinical experience

AU - Herms, Elena

AU - Weirich, Gregor

AU - Maurer, Tobias

AU - Wagenpfeil, Stefan

AU - Preuss, Stephanie

AU - Sauter, Andreas

AU - Heck, Matthias

AU - Gärtner, Anita

AU - Hauner, Katharina

AU - Autenrieth, Michael

AU - Kübler, Hubert P

AU - Holzapfel, Konstantin

AU - Schwarz-Boeger, Ulrike

AU - Heemann, Uwe

AU - Slotta-Huspenina, Julia

AU - Stock, Konrad Friedrich

N1 - © 2022. The Author(s).

PY - 2023/3

Y1 - 2023/3

N2 - PURPOSE: Renal cysts comprise benign and malignant entities. Risk assessment profits from CT/MRI imaging using the Bosniak classification. While Bosniak-IIF, -III, and -IV cover complex cyst variants, Bosniak-IIF and -III stand out due to notorious overestimation. Contrast-enhanced ultrasound (CEUS) is promising to overcome this deficit but warrants standardization. This study addresses the benefits of a combined CEUS and CT/MRI evaluation of renal cysts. The study provides a realistic account of kidney tumor boards' intricacies in trying to validate renal cysts.METHODS: 247 patients were examined over 8 years. CEUS lesions were graded according to CEUS-Bosniak (IIF, III, IV). 55 lesions were resected, CEUS-Bosniak- and CT/MRI-Bosniak-classification were correlated with histopathological diagnosis. Interobserver agreement between the classifications was evaluated statistically. 105 lesions were followed by ultrasound, and change in CEUS-Bosniak-types and lesion size were documented.RESULTS: 146 patients (156 lesions) were included. CEUS classified 67 lesions as CEUS-Bosniak-IIF, 44 as CEUS-Bosniak-III, and 45 as CEUS-Bosniak-IV. Histopathology of 55 resected lesions revealed benign cysts in all CEUS-Bosniak-IIF lesions (2/2), 40% of CEUS-Bosniak-III and 8% of CEUS-Bosniak-IV, whereas malignancy was uncovered in 60% of CEUS-Bosniak-III and 92% of CEUS-Bosniak-IV. Overall, CEUS-Bosniak-types matched CT/MRI-Bosniak types in 58% (fair agreement, κ = 0.28). CEUS-Bosniak resulted in higher stages than CT/MRI-Bosniak (40%). Ultrasound follow-up of 105 lesions detected no relevant differences between CEUS-Bosniak-types concerning cysts size. 99% of lesions showed the same CEUS-Bosniak-type.CONCLUSION: The CEUS-Bosniak classification is an essential tool in clinical practice to differentiate and monitor renal cystic lesions and empowers diagnostic work-up and patient care.

AB - PURPOSE: Renal cysts comprise benign and malignant entities. Risk assessment profits from CT/MRI imaging using the Bosniak classification. While Bosniak-IIF, -III, and -IV cover complex cyst variants, Bosniak-IIF and -III stand out due to notorious overestimation. Contrast-enhanced ultrasound (CEUS) is promising to overcome this deficit but warrants standardization. This study addresses the benefits of a combined CEUS and CT/MRI evaluation of renal cysts. The study provides a realistic account of kidney tumor boards' intricacies in trying to validate renal cysts.METHODS: 247 patients were examined over 8 years. CEUS lesions were graded according to CEUS-Bosniak (IIF, III, IV). 55 lesions were resected, CEUS-Bosniak- and CT/MRI-Bosniak-classification were correlated with histopathological diagnosis. Interobserver agreement between the classifications was evaluated statistically. 105 lesions were followed by ultrasound, and change in CEUS-Bosniak-types and lesion size were documented.RESULTS: 146 patients (156 lesions) were included. CEUS classified 67 lesions as CEUS-Bosniak-IIF, 44 as CEUS-Bosniak-III, and 45 as CEUS-Bosniak-IV. Histopathology of 55 resected lesions revealed benign cysts in all CEUS-Bosniak-IIF lesions (2/2), 40% of CEUS-Bosniak-III and 8% of CEUS-Bosniak-IV, whereas malignancy was uncovered in 60% of CEUS-Bosniak-III and 92% of CEUS-Bosniak-IV. Overall, CEUS-Bosniak-types matched CT/MRI-Bosniak types in 58% (fair agreement, κ = 0.28). CEUS-Bosniak resulted in higher stages than CT/MRI-Bosniak (40%). Ultrasound follow-up of 105 lesions detected no relevant differences between CEUS-Bosniak-types concerning cysts size. 99% of lesions showed the same CEUS-Bosniak-type.CONCLUSION: The CEUS-Bosniak classification is an essential tool in clinical practice to differentiate and monitor renal cystic lesions and empowers diagnostic work-up and patient care.

U2 - 10.1007/s00345-022-04094-0

DO - 10.1007/s00345-022-04094-0

M3 - SCORING: Journal article

C2 - 35986781

VL - 41

SP - 679

EP - 685

JO - WORLD J UROL

JF - WORLD J UROL

SN - 0724-4983

IS - 3

ER -