Progress in the development of vision prostheses.
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Progress in the development of vision prostheses. / Matthaei, Mario; Zeitz, Oliver; Keserü, Matthias; Wagenfeld, Lars; Hornig, Ralf; Post, Nils; Richard, Gisbert.
In: OPHTHALMOLOGICA, Vol. 225, No. 4, 4, 2011, p. 187-192.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Progress in the development of vision prostheses.
AU - Matthaei, Mario
AU - Zeitz, Oliver
AU - Keserü, Matthias
AU - Wagenfeld, Lars
AU - Hornig, Ralf
AU - Post, Nils
AU - Richard, Gisbert
PY - 2011
Y1 - 2011
N2 - Degenerative retinal diseases like retinitis pigmentosa and age-related macular degeneration are among the most common causes of blindness worldwide. Electronic visual prostheses represent a potential therapeutic option of increasing importance in otherwise incurably impaired patients. Based on extensive animal experiments, several devices are now being tested in clinical trials. According to the placement of the electrodes, possible stimulation sites are located subretinally, epiretinally, along the optic nerve or cortically. Anatomical, physiological and pathophysiological aspects must be considered in development and clinical application. To provide an appropriate retinal substitute, the optimal integration and adaptation of the prosthesis into the highly complex system of the visual pathway is important. This article aims to summarize the relevant studies and provides an overview of the current status of developments and challenges that still need to be mastered.
AB - Degenerative retinal diseases like retinitis pigmentosa and age-related macular degeneration are among the most common causes of blindness worldwide. Electronic visual prostheses represent a potential therapeutic option of increasing importance in otherwise incurably impaired patients. Based on extensive animal experiments, several devices are now being tested in clinical trials. According to the placement of the electrodes, possible stimulation sites are located subretinally, epiretinally, along the optic nerve or cortically. Anatomical, physiological and pathophysiological aspects must be considered in development and clinical application. To provide an appropriate retinal substitute, the optimal integration and adaptation of the prosthesis into the highly complex system of the visual pathway is important. This article aims to summarize the relevant studies and provides an overview of the current status of developments and challenges that still need to be mastered.
M3 - SCORING: Journal article
VL - 225
SP - 187
EP - 192
JO - OPHTHALMOLOGICA
JF - OPHTHALMOLOGICA
SN - 0030-3755
IS - 4
M1 - 4
ER -