Optimization of intraocular lens constant improves refractive outcomes in combined endothelial keratoplasty and cataract surgery

Gustavo Bonfadini; John G Ladas; Hamilton Moreira; Mauro Campos; Mario Matthaei; Beatriz Muñoz; Kim Pratzer; Albert S Jun

doi:10.1016/j.ophtha.2012.08.003

Optimization of intraocular lens constant improves refractive outcomes in combined endothelial keratoplasty and cataract surgery

Standard

Optimization of intraocular lens constant improves refractive outcomes in combined endothelial keratoplasty and cataract surgery. / Bonfadini, Gustavo; Ladas, John G; Moreira, Hamilton; Campos, Mauro; Matthaei, Mario; Muñoz, Beatriz; Pratzer, Kim; Jun, Albert S.

In: OPHTHALMOLOGY, Vol. 120, No. 2, 01.02.2013, p. 234-9.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Bonfadini, G, Ladas, JG, Moreira, H, Campos, M, Matthaei, M, Muñoz, B, Pratzer, K & Jun, AS 2013, 'Optimization of intraocular lens constant improves refractive outcomes in combined endothelial keratoplasty and cataract surgery', OPHTHALMOLOGY, vol. 120, no. 2, pp. 234-9. https://doi.org/10.1016/j.ophtha.2012.08.003

APA

Bonfadini, G., Ladas, J. G., Moreira, H., Campos, M., Matthaei, M., Muñoz, B., Pratzer, K., & Jun, A. S. (2013). Optimization of intraocular lens constant improves refractive outcomes in combined endothelial keratoplasty and cataract surgery. OPHTHALMOLOGY, 120(2), 234-9. https://doi.org/10.1016/j.ophtha.2012.08.003

Vancouver

Bonfadini G, Ladas JG, Moreira H, Campos M, Matthaei M, Muñoz B et al. Optimization of intraocular lens constant improves refractive outcomes in combined endothelial keratoplasty and cataract surgery. OPHTHALMOLOGY. 2013 Feb 1;120(2):234-9. https://doi.org/10.1016/j.ophtha.2012.08.003

Bibtex

@article{56eb204e71bd490e8c9d0a930d59944c,

title = "Optimization of intraocular lens constant improves refractive outcomes in combined endothelial keratoplasty and cataract surgery",

abstract = "PURPOSE: To evaluate the accuracy of intraocular lens (IOL) power calculations with A-constant optimization in Descemet's stripping automated endothelial keratoplasty (DSAEK) combined with cataract extraction and intraocular lens implantation (DSAEK triple procedure).DESIGN: Retrospective case series.PARTICIPANTS: Thirty eyes of 22 patients with Fuchs' endothelial dystrophy who underwent the DSAEK triple procedure performed by a single surgeon.METHODS: Prediction errors were calculated retrospectively for consecutive DSAEK triple procedures. These prediction errors then were used to determine an IOL constant for this cohort of patients. The new optimized IOL constant subsequently was compared with the manufacturer's IOL constant, allowing evaluation and quantification of refractive benefits of optimization.MAIN OUTCOMES MEASURES: The error in diopters (D) of the predicted refraction with the manufacturer's and optimized IOL constants.RESULTS: Optimization of the A constant decreased the mean absolute error (MAE) from 1.09 ± 0.63 D (range, 0.12-2.41 D) to 0.61 ± 0.4 D (range, 0-1.58 D; P = 0.004). Comparing the intended and final postoperative refractions calculated with the original manufacturer's constant and the optimized constant, 20% versus 43% of all eyes were in the less than 0.5-D range and 50% versus 83% of all eyes were in the less than 1.0-D range of the target refraction. Furthermore, optimization decreased the number of eyes that were more than 1.0 D from the target refraction from 50% to 17%.CONCLUSIONS: Optimization of the IOL constant showed significantly improved accuracy of predicted postoperative refraction compared with the manufacturer's IOL constant, which may help improve the postoperative refractive outcomes in patients undergoing the DSAEK triple procedure.",

keywords = "Aged, Aged, 80 and over, Biometry, Cataract, Descemet Stripping Endothelial Keratoplasty, Female, Fuchs' Endothelial Dystrophy, Humans, Keratoplasty, Penetrating, Lens Implantation, Intraocular, Lenses, Intraocular, Male, Middle Aged, Optics and Photonics, Pseudophakia, Refraction, Ocular, Reproducibility of Results, Retrospective Studies, Treatment Outcome, Visual Acuity",

author = "Gustavo Bonfadini and Ladas, {John G} and Hamilton Moreira and Mauro Campos and Mario Matthaei and Beatriz Mu{\~n}oz and Kim Pratzer and Jun, {Albert S}",

year = "2013",

month = feb,

day = "1",

doi = "10.1016/j.ophtha.2012.08.003",

language = "English",

volume = "120",

pages = "234--9",

journal = "OPHTHALMOLOGY",

issn = "0161-6420",

publisher = "Elsevier Inc.",

number = "2",

}

RIS

TY - JOUR

T1 - Optimization of intraocular lens constant improves refractive outcomes in combined endothelial keratoplasty and cataract surgery

AU - Bonfadini, Gustavo

AU - Ladas, John G

AU - Moreira, Hamilton

AU - Campos, Mauro

AU - Matthaei, Mario

AU - Muñoz, Beatriz

AU - Pratzer, Kim

AU - Jun, Albert S

PY - 2013/2/1

Y1 - 2013/2/1

N2 - PURPOSE: To evaluate the accuracy of intraocular lens (IOL) power calculations with A-constant optimization in Descemet's stripping automated endothelial keratoplasty (DSAEK) combined with cataract extraction and intraocular lens implantation (DSAEK triple procedure).DESIGN: Retrospective case series.PARTICIPANTS: Thirty eyes of 22 patients with Fuchs' endothelial dystrophy who underwent the DSAEK triple procedure performed by a single surgeon.METHODS: Prediction errors were calculated retrospectively for consecutive DSAEK triple procedures. These prediction errors then were used to determine an IOL constant for this cohort of patients. The new optimized IOL constant subsequently was compared with the manufacturer's IOL constant, allowing evaluation and quantification of refractive benefits of optimization.MAIN OUTCOMES MEASURES: The error in diopters (D) of the predicted refraction with the manufacturer's and optimized IOL constants.RESULTS: Optimization of the A constant decreased the mean absolute error (MAE) from 1.09 ± 0.63 D (range, 0.12-2.41 D) to 0.61 ± 0.4 D (range, 0-1.58 D; P = 0.004). Comparing the intended and final postoperative refractions calculated with the original manufacturer's constant and the optimized constant, 20% versus 43% of all eyes were in the less than 0.5-D range and 50% versus 83% of all eyes were in the less than 1.0-D range of the target refraction. Furthermore, optimization decreased the number of eyes that were more than 1.0 D from the target refraction from 50% to 17%.CONCLUSIONS: Optimization of the IOL constant showed significantly improved accuracy of predicted postoperative refraction compared with the manufacturer's IOL constant, which may help improve the postoperative refractive outcomes in patients undergoing the DSAEK triple procedure.

AB - PURPOSE: To evaluate the accuracy of intraocular lens (IOL) power calculations with A-constant optimization in Descemet's stripping automated endothelial keratoplasty (DSAEK) combined with cataract extraction and intraocular lens implantation (DSAEK triple procedure).DESIGN: Retrospective case series.PARTICIPANTS: Thirty eyes of 22 patients with Fuchs' endothelial dystrophy who underwent the DSAEK triple procedure performed by a single surgeon.METHODS: Prediction errors were calculated retrospectively for consecutive DSAEK triple procedures. These prediction errors then were used to determine an IOL constant for this cohort of patients. The new optimized IOL constant subsequently was compared with the manufacturer's IOL constant, allowing evaluation and quantification of refractive benefits of optimization.MAIN OUTCOMES MEASURES: The error in diopters (D) of the predicted refraction with the manufacturer's and optimized IOL constants.RESULTS: Optimization of the A constant decreased the mean absolute error (MAE) from 1.09 ± 0.63 D (range, 0.12-2.41 D) to 0.61 ± 0.4 D (range, 0-1.58 D; P = 0.004). Comparing the intended and final postoperative refractions calculated with the original manufacturer's constant and the optimized constant, 20% versus 43% of all eyes were in the less than 0.5-D range and 50% versus 83% of all eyes were in the less than 1.0-D range of the target refraction. Furthermore, optimization decreased the number of eyes that were more than 1.0 D from the target refraction from 50% to 17%.CONCLUSIONS: Optimization of the IOL constant showed significantly improved accuracy of predicted postoperative refraction compared with the manufacturer's IOL constant, which may help improve the postoperative refractive outcomes in patients undergoing the DSAEK triple procedure.

KW - Aged

KW - Aged, 80 and over

KW - Biometry

KW - Cataract

KW - Descemet Stripping Endothelial Keratoplasty

KW - Female

KW - Fuchs' Endothelial Dystrophy

KW - Humans

KW - Keratoplasty, Penetrating

KW - Lens Implantation, Intraocular

KW - Lenses, Intraocular

KW - Male

KW - Middle Aged

KW - Optics and Photonics

KW - Pseudophakia

KW - Refraction, Ocular

KW - Reproducibility of Results

KW - Retrospective Studies

KW - Treatment Outcome

KW - Visual Acuity

U2 - 10.1016/j.ophtha.2012.08.003

DO - 10.1016/j.ophtha.2012.08.003

M3 - SCORING: Journal article

C2 - 23107582

VL - 120

SP - 234

EP - 239

JO - OPHTHALMOLOGY

JF - OPHTHALMOLOGY

SN - 0161-6420

IS - 2

ER -