Occupational asbestos exposure as a risk factor for laryngeal carcinoma in a population-based case-control study from Germany

Standard

Occupational asbestos exposure as a risk factor for laryngeal carcinoma in a population-based case-control study from Germany. / Ramroth, Heribert; Ahrens, Wolfgang; Dietz, Andreas; Becher, Heiko.

In: AM J IND MED, Vol. 54, No. 7, 01.07.2011, p. 510-4.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

APA

Vancouver

Bibtex

@article{9205deab598a4150a0ad0247d012bdea,
title = "Occupational asbestos exposure as a risk factor for laryngeal carcinoma in a population-based case-control study from Germany",
abstract = "BACKGROUND: As several studies have identified asbestos exposure as an independent occupational risk factor for laryngeal cancer, the aim of our study was to confirm this association.METHODS: In a population-based case-control study on laryngeal cancer in South-West Germany occupational exposures and other risk factors were obtained by face-to-face interviews using a detailed standardized questionnaire covering the complete individual working history, supplemented by job-specific questionnaires (JSQ) especially for selected jobs known to entail exposure to asbestos. Detailed exposure information was collected over a wide range of asbestos related jobs and branches and analyzed using different modeling strategies.RESULTS: Seventy-three (28.4%) cases and 158 (20.5%) controls reported any exposure to asbestos. Elevated risk estimates for asbestos exposure were found. However, those became substantially reduced after adjustment for smoking and alcohol.CONCLUSION: Moderately elevated risks for laryngeal cancer after exposure to asbestos were confirmed. Difficulties in the collection of adequate exposure data were demonstrated.",
keywords = "Aged, Asbestos, Case-Control Studies, Confidence Intervals, Female, Germany, Humans, Laryngeal Neoplasms, Logistic Models, Male, Middle Aged, Occupational Diseases, Occupational Exposure, Odds Ratio, Questionnaires, Risk Factors",
author = "Heribert Ramroth and Wolfgang Ahrens and Andreas Dietz and Heiko Becher",
note = "Copyright {\textcopyright} 2011 Wiley-Liss, Inc.",
year = "2011",
month = jul,
day = "1",
doi = "10.1002/ajim.20963",
language = "English",
volume = "54",
pages = "510--4",
journal = "AM J IND MED",
issn = "0271-3586",
publisher = "Wiley-Liss Inc.",
number = "7",

}

RIS

TY - JOUR

T1 - Occupational asbestos exposure as a risk factor for laryngeal carcinoma in a population-based case-control study from Germany

AU - Ramroth, Heribert

AU - Ahrens, Wolfgang

AU - Dietz, Andreas

AU - Becher, Heiko

N1 - Copyright © 2011 Wiley-Liss, Inc.

PY - 2011/7/1

Y1 - 2011/7/1

N2 - BACKGROUND: As several studies have identified asbestos exposure as an independent occupational risk factor for laryngeal cancer, the aim of our study was to confirm this association.METHODS: In a population-based case-control study on laryngeal cancer in South-West Germany occupational exposures and other risk factors were obtained by face-to-face interviews using a detailed standardized questionnaire covering the complete individual working history, supplemented by job-specific questionnaires (JSQ) especially for selected jobs known to entail exposure to asbestos. Detailed exposure information was collected over a wide range of asbestos related jobs and branches and analyzed using different modeling strategies.RESULTS: Seventy-three (28.4%) cases and 158 (20.5%) controls reported any exposure to asbestos. Elevated risk estimates for asbestos exposure were found. However, those became substantially reduced after adjustment for smoking and alcohol.CONCLUSION: Moderately elevated risks for laryngeal cancer after exposure to asbestos were confirmed. Difficulties in the collection of adequate exposure data were demonstrated.

AB - BACKGROUND: As several studies have identified asbestos exposure as an independent occupational risk factor for laryngeal cancer, the aim of our study was to confirm this association.METHODS: In a population-based case-control study on laryngeal cancer in South-West Germany occupational exposures and other risk factors were obtained by face-to-face interviews using a detailed standardized questionnaire covering the complete individual working history, supplemented by job-specific questionnaires (JSQ) especially for selected jobs known to entail exposure to asbestos. Detailed exposure information was collected over a wide range of asbestos related jobs and branches and analyzed using different modeling strategies.RESULTS: Seventy-three (28.4%) cases and 158 (20.5%) controls reported any exposure to asbestos. Elevated risk estimates for asbestos exposure were found. However, those became substantially reduced after adjustment for smoking and alcohol.CONCLUSION: Moderately elevated risks for laryngeal cancer after exposure to asbestos were confirmed. Difficulties in the collection of adequate exposure data were demonstrated.

KW - Aged

KW - Asbestos

KW - Case-Control Studies

KW - Confidence Intervals

KW - Female

KW - Germany

KW - Humans

KW - Laryngeal Neoplasms

KW - Logistic Models

KW - Male

KW - Middle Aged

KW - Occupational Diseases

KW - Occupational Exposure

KW - Odds Ratio

KW - Questionnaires

KW - Risk Factors

U2 - 10.1002/ajim.20963

DO - 10.1002/ajim.20963

M3 - SCORING: Journal article

C2 - 21538446

VL - 54

SP - 510

EP - 514

JO - AM J IND MED

JF - AM J IND MED

SN - 0271-3586

IS - 7

ER -