Intensity and inhalation of smoking in the aetiology of laryngeal cancer

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Intensity and inhalation of smoking in the aetiology of laryngeal cancer. / Ramroth, Heribert; Dietz, Andreas; Becher, Heiko.

In: INT J ENV RES PUB HE, Vol. 8, No. 4, 01.04.2011, p. 976-84.

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@article{e244ee1c0eff41a492c5e171156f60d1,
title = "Intensity and inhalation of smoking in the aetiology of laryngeal cancer",
abstract = "The carcinogenic effect of smoking on laryngeal cancer is well established; however, the risk pattern for detailed smoking characteristics is less clear. Thus, the aim of this analysis was to quantify the impact of different inhalation behaviours on the risk of laryngeal cancer. We conducted a population-based case control study in Germany, frequency-matched for sex and age, using a standardized questionnaire covering lifelong smoking details, including age at start, time since quitting, types of smoking products, duration, intensity and inhalation behaviour. We found higher risks for increasing duration and intensity of smoking. A clear dose-response relationship was found in all inhalation subgroups, i.e., not only for deep inhalers, but also for those puffing on a cigarette. Clearly reduced risks could be observed for quitting smoking. Changing inhalation habits might be considered as a first step to reducing the risk of developing laryngeal cancer. However, the best way to effectively reduce laryngeal cancer risk is to quit smoking.",
keywords = "Aged, Alcohol Drinking, Case-Control Studies, Female, Germany, Humans, Inhalation, Laryngeal Neoplasms, Male, Middle Aged, Risk Factors, Smoking",
author = "Heribert Ramroth and Andreas Dietz and Heiko Becher",
year = "2011",
month = apr,
day = "1",
doi = "10.3390/ijerph8040976",
language = "English",
volume = "8",
pages = "976--84",
journal = "INT J ENV RES PUB HE",
issn = "1660-4601",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "4",

}

RIS

TY - JOUR

T1 - Intensity and inhalation of smoking in the aetiology of laryngeal cancer

AU - Ramroth, Heribert

AU - Dietz, Andreas

AU - Becher, Heiko

PY - 2011/4/1

Y1 - 2011/4/1

N2 - The carcinogenic effect of smoking on laryngeal cancer is well established; however, the risk pattern for detailed smoking characteristics is less clear. Thus, the aim of this analysis was to quantify the impact of different inhalation behaviours on the risk of laryngeal cancer. We conducted a population-based case control study in Germany, frequency-matched for sex and age, using a standardized questionnaire covering lifelong smoking details, including age at start, time since quitting, types of smoking products, duration, intensity and inhalation behaviour. We found higher risks for increasing duration and intensity of smoking. A clear dose-response relationship was found in all inhalation subgroups, i.e., not only for deep inhalers, but also for those puffing on a cigarette. Clearly reduced risks could be observed for quitting smoking. Changing inhalation habits might be considered as a first step to reducing the risk of developing laryngeal cancer. However, the best way to effectively reduce laryngeal cancer risk is to quit smoking.

AB - The carcinogenic effect of smoking on laryngeal cancer is well established; however, the risk pattern for detailed smoking characteristics is less clear. Thus, the aim of this analysis was to quantify the impact of different inhalation behaviours on the risk of laryngeal cancer. We conducted a population-based case control study in Germany, frequency-matched for sex and age, using a standardized questionnaire covering lifelong smoking details, including age at start, time since quitting, types of smoking products, duration, intensity and inhalation behaviour. We found higher risks for increasing duration and intensity of smoking. A clear dose-response relationship was found in all inhalation subgroups, i.e., not only for deep inhalers, but also for those puffing on a cigarette. Clearly reduced risks could be observed for quitting smoking. Changing inhalation habits might be considered as a first step to reducing the risk of developing laryngeal cancer. However, the best way to effectively reduce laryngeal cancer risk is to quit smoking.

KW - Aged

KW - Alcohol Drinking

KW - Case-Control Studies

KW - Female

KW - Germany

KW - Humans

KW - Inhalation

KW - Laryngeal Neoplasms

KW - Male

KW - Middle Aged

KW - Risk Factors

KW - Smoking

U2 - 10.3390/ijerph8040976

DO - 10.3390/ijerph8040976

M3 - SCORING: Journal article

C2 - 21695025

VL - 8

SP - 976

EP - 984

JO - INT J ENV RES PUB HE

JF - INT J ENV RES PUB HE

SN - 1660-4601

IS - 4

ER -