Identification of alternatively spliced Dab1 and Fyn isoforms in pig.

  • Huan Long
  • Hans H Bock
  • Ting Lei
  • Xuejun Chai
  • Jihong Yuan
  • Joachim Herz
  • Michael Frotscher
  • Zaiqing Yang

Abstract

Disabled-1 (Dab1) is an adaptor protein that is essential for the intracellular transduction of Reelin signaling, which regulates the migration and differentiation of postmitotic neurons during brain development in vertebrates. Dab1 function depends on its tyrosine phosphorylation by Src family kinases, especially Fyn.

Bibliographical data

Original languageEnglish
ISSN1471-2202
DOIs
Publication statusPublished - 2011
pubmed 21294906