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D-dimer levels for risk stratification in patients with suspected covid-19 - a prospective observational study

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D-dimer levels for risk stratification in patients with suspected covid-19 - a prospective observational study. / Jauslin, Andrea S.; Kellett, John; Brabrand, Mikkel; Simon, Noemi R.; Rueegg, Marco; Twerenbold, Raphael; Osswald, Stefan; Bassetti, Stefano; Tschudin-Sutter, Sarah; Siegemund, Martin; Rentsch, Katharina; Bingisser, Roland; Nickel, Christian H.

In: Acute Medicine, Vol. 20, No. 3, 2021, p. 193-203.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Jauslin, AS, Kellett, J, Brabrand, M, Simon, NR, Rueegg, M, Twerenbold, R, Osswald, S, Bassetti, S, Tschudin-Sutter, S, Siegemund, M, Rentsch, K, Bingisser, R & Nickel, CH 2021, 'D-dimer levels for risk stratification in patients with suspected covid-19 - a prospective observational study', Acute Medicine, vol. 20, no. 3, pp. 193-203. https://doi.org/10.52964/AMJA.0864

APA

Jauslin, A. S., Kellett, J., Brabrand, M., Simon, N. R., Rueegg, M., Twerenbold, R., Osswald, S., Bassetti, S., Tschudin-Sutter, S., Siegemund, M., Rentsch, K., Bingisser, R., & Nickel, C. H. (2021). D-dimer levels for risk stratification in patients with suspected covid-19 - a prospective observational study. Acute Medicine, 20(3), 193-203. https://doi.org/10.52964/AMJA.0864

Vancouver

Jauslin AS, Kellett J, Brabrand M, Simon NR, Rueegg M, Twerenbold R et al. D-dimer levels for risk stratification in patients with suspected covid-19 - a prospective observational study. Acute Medicine. 2021;20(3):193-203. https://doi.org/10.52964/AMJA.0864

Bibtex

@article{ae0350af5733485382c1762d106a402a,
title = "D-dimer levels for risk stratification in patients with suspected covid-19 - a prospective observational study",
abstract = "Background: Elevated D-dimer levels have been observed in COVID-19 and are of prognostic value, but have not been compared to an appropriate control group. Methods: Observational cohort study including emergency patients with suspected or confirmed COVID-19. Logistic regression defined the association of D-dimer levels, COVID-19 positivity, age, and gender with 30-day-mortality. Results: 953 consecutive patients (median age 58, 43% women) presented with suspected COVID-19: 12 (7.4%) patients with confirmed SARS-CoV-2-infection died, compared with 28 (3.5%) patients without SARS-CoV-2-infection. Overall, most (56%) patients had elevated D-dimer levels (≥0.5mg/l). Age (OR 1.07, CI 1.05-1.10), D-dimer levels ≥0.5mg/l (OR 2.44, CI 0.98-7.39), and COVID-19 (OR 2.79, CI 1.28-5.80) were associated with 30-day-mortality. Conclusion: D-dimer levels are effective prognosticators in both patient groups. ",
keywords = "COVID-19, D-dimer levels, NEWS, prognosis, risk-stratification",
author = "Jauslin, {Andrea S.} and John Kellett and Mikkel Brabrand and Simon, {Noemi R.} and Marco Rueegg and Raphael Twerenbold and Stefan Osswald and Stefano Bassetti and Sarah Tschudin-Sutter and Martin Siegemund and Katharina Rentsch and Roland Bingisser and Nickel, {Christian H.}",
note = "Publisher Copyright: {\textcopyright} 2021 Rila Publications Ltd.",
year = "2021",
doi = "10.52964/AMJA.0864",
language = "English",
volume = "20",
pages = "193--203",
journal = "Acute Medicine",
issn = "1747-4884",
publisher = "Rila Publications Ltd",
number = "3",

}

RIS

TY - JOUR

T1 - D-dimer levels for risk stratification in patients with suspected covid-19 - a prospective observational study

AU - Jauslin, Andrea S.

AU - Kellett, John

AU - Brabrand, Mikkel

AU - Simon, Noemi R.

AU - Rueegg, Marco

AU - Twerenbold, Raphael

AU - Osswald, Stefan

AU - Bassetti, Stefano

AU - Tschudin-Sutter, Sarah

AU - Siegemund, Martin

AU - Rentsch, Katharina

AU - Bingisser, Roland

AU - Nickel, Christian H.

N1 - Publisher Copyright: © 2021 Rila Publications Ltd.

PY - 2021

Y1 - 2021

N2 - Background: Elevated D-dimer levels have been observed in COVID-19 and are of prognostic value, but have not been compared to an appropriate control group. Methods: Observational cohort study including emergency patients with suspected or confirmed COVID-19. Logistic regression defined the association of D-dimer levels, COVID-19 positivity, age, and gender with 30-day-mortality. Results: 953 consecutive patients (median age 58, 43% women) presented with suspected COVID-19: 12 (7.4%) patients with confirmed SARS-CoV-2-infection died, compared with 28 (3.5%) patients without SARS-CoV-2-infection. Overall, most (56%) patients had elevated D-dimer levels (≥0.5mg/l). Age (OR 1.07, CI 1.05-1.10), D-dimer levels ≥0.5mg/l (OR 2.44, CI 0.98-7.39), and COVID-19 (OR 2.79, CI 1.28-5.80) were associated with 30-day-mortality. Conclusion: D-dimer levels are effective prognosticators in both patient groups.

AB - Background: Elevated D-dimer levels have been observed in COVID-19 and are of prognostic value, but have not been compared to an appropriate control group. Methods: Observational cohort study including emergency patients with suspected or confirmed COVID-19. Logistic regression defined the association of D-dimer levels, COVID-19 positivity, age, and gender with 30-day-mortality. Results: 953 consecutive patients (median age 58, 43% women) presented with suspected COVID-19: 12 (7.4%) patients with confirmed SARS-CoV-2-infection died, compared with 28 (3.5%) patients without SARS-CoV-2-infection. Overall, most (56%) patients had elevated D-dimer levels (≥0.5mg/l). Age (OR 1.07, CI 1.05-1.10), D-dimer levels ≥0.5mg/l (OR 2.44, CI 0.98-7.39), and COVID-19 (OR 2.79, CI 1.28-5.80) were associated with 30-day-mortality. Conclusion: D-dimer levels are effective prognosticators in both patient groups.

KW - COVID-19

KW - D-dimer levels

KW - NEWS

KW - prognosis

KW - risk-stratification

UR - http://www.scopus.com/inward/record.url?scp=85119685214&partnerID=8YFLogxK

U2 - 10.52964/AMJA.0864

DO - 10.52964/AMJA.0864

M3 - SCORING: Journal article

C2 - 34679137

AN - SCOPUS:85119685214

VL - 20

SP - 193

EP - 203

JO - Acute Medicine

JF - Acute Medicine

SN - 1747-4884

IS - 3

ER -