Research ExplorerPublicationsContinuous intra-arterial nimodipine infusion in refractory ...

Continuous intra-arterial nimodipine infusion in refractory symptomatic vasospasm after subarachnoid hemorrhage

Standard

Continuous intra-arterial nimodipine infusion in refractory symptomatic vasospasm after subarachnoid hemorrhage. / Helbok, Raimund; Zangerle, Alexandra; Chemelli, Andreas; Beer, Ronny; Benke, Thomas; Ehling, Rainer; Fischer, Marlene; Sojer, Martin; Pfausler, Bettina; Thome, Claudius; Schmutzhard, Erich.

In: SPRINGERPLUS, Vol. 5, No. 1, 2016, p. 1807.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Helbok, R, Zangerle, A, Chemelli, A, Beer, R, Benke, T, Ehling, R, Fischer, M, Sojer, M, Pfausler, B, Thome, C & Schmutzhard, E 2016, 'Continuous intra-arterial nimodipine infusion in refractory symptomatic vasospasm after subarachnoid hemorrhage', SPRINGERPLUS, vol. 5, no. 1, pp. 1807. https://doi.org/10.1186/s40064-016-3495-4

APA

Helbok, R., Zangerle, A., Chemelli, A., Beer, R., Benke, T., Ehling, R., Fischer, M., Sojer, M., Pfausler, B., Thome, C., & Schmutzhard, E. (2016). Continuous intra-arterial nimodipine infusion in refractory symptomatic vasospasm after subarachnoid hemorrhage. SPRINGERPLUS, 5(1), 1807. https://doi.org/10.1186/s40064-016-3495-4

Vancouver

Helbok R, Zangerle A, Chemelli A, Beer R, Benke T, Ehling R et al. Continuous intra-arterial nimodipine infusion in refractory symptomatic vasospasm after subarachnoid hemorrhage. SPRINGERPLUS. 2016;5(1):1807. https://doi.org/10.1186/s40064-016-3495-4

Bibtex

@article{67128d97c14d44b6ad366e1e19332932,
title = "Continuous intra-arterial nimodipine infusion in refractory symptomatic vasospasm after subarachnoid hemorrhage",
abstract = "INTRODUCTION: Vasospasm still is a major cause of morbidity after aneurysmal subarachnoid hemorrhage. The purpose of this report is to describe the successful management of severe refractory vasospasm with continuous intra-arterial nimodipine (IAN) treatment.CASE DESCRIPTION: A 72-year old right handed woman was admitted with non-traumatic SAH WFNS grade 1. Cerebral computed tomography demonstrated thick blood filling of the basal cisterns, and intraventricular hemorrhage. Cerebral angiogram failed to detect a vascular abnormality. After an uneventful initial course the patient developed symptomatic left middle cerebral artery vasospasm with aphasia and corresponding restriction in diffusion weighted images in the left frontal lobe. Bolus IAN only transiently improved cerebral circulation and clinical signs and symptoms. Continuous-IAN was started and led to full clinical recovery and normalisation of MRI diffusion restrictions.DISCUSSION AND CONCLUSIONS: Continuous selective intra-arterial infusion of nimodipine may be an option in selected patients with symptomatic vasospasm refractory to conventional treatment after careful consideration of benefits and procedure-related risks.",
author = "Raimund Helbok and Alexandra Zangerle and Andreas Chemelli and Ronny Beer and Thomas Benke and Rainer Ehling and Marlene Fischer and Martin Sojer and Bettina Pfausler and Claudius Thome and Erich Schmutzhard",
year = "2016",
doi = "10.1186/s40064-016-3495-4",
language = "English",
volume = "5",
pages = "1807",
journal = "SPRINGERPLUS",
issn = "2193-1801",
publisher = "Springer Science and Business Media Deutschland GmbH",
number = "1",

}

RIS

TY - JOUR

T1 - Continuous intra-arterial nimodipine infusion in refractory symptomatic vasospasm after subarachnoid hemorrhage

AU - Helbok, Raimund

AU - Zangerle, Alexandra

AU - Chemelli, Andreas

AU - Beer, Ronny

AU - Benke, Thomas

AU - Ehling, Rainer

AU - Fischer, Marlene

AU - Sojer, Martin

AU - Pfausler, Bettina

AU - Thome, Claudius

AU - Schmutzhard, Erich

PY - 2016

Y1 - 2016

N2 - INTRODUCTION: Vasospasm still is a major cause of morbidity after aneurysmal subarachnoid hemorrhage. The purpose of this report is to describe the successful management of severe refractory vasospasm with continuous intra-arterial nimodipine (IAN) treatment.CASE DESCRIPTION: A 72-year old right handed woman was admitted with non-traumatic SAH WFNS grade 1. Cerebral computed tomography demonstrated thick blood filling of the basal cisterns, and intraventricular hemorrhage. Cerebral angiogram failed to detect a vascular abnormality. After an uneventful initial course the patient developed symptomatic left middle cerebral artery vasospasm with aphasia and corresponding restriction in diffusion weighted images in the left frontal lobe. Bolus IAN only transiently improved cerebral circulation and clinical signs and symptoms. Continuous-IAN was started and led to full clinical recovery and normalisation of MRI diffusion restrictions.DISCUSSION AND CONCLUSIONS: Continuous selective intra-arterial infusion of nimodipine may be an option in selected patients with symptomatic vasospasm refractory to conventional treatment after careful consideration of benefits and procedure-related risks.

AB - INTRODUCTION: Vasospasm still is a major cause of morbidity after aneurysmal subarachnoid hemorrhage. The purpose of this report is to describe the successful management of severe refractory vasospasm with continuous intra-arterial nimodipine (IAN) treatment.CASE DESCRIPTION: A 72-year old right handed woman was admitted with non-traumatic SAH WFNS grade 1. Cerebral computed tomography demonstrated thick blood filling of the basal cisterns, and intraventricular hemorrhage. Cerebral angiogram failed to detect a vascular abnormality. After an uneventful initial course the patient developed symptomatic left middle cerebral artery vasospasm with aphasia and corresponding restriction in diffusion weighted images in the left frontal lobe. Bolus IAN only transiently improved cerebral circulation and clinical signs and symptoms. Continuous-IAN was started and led to full clinical recovery and normalisation of MRI diffusion restrictions.DISCUSSION AND CONCLUSIONS: Continuous selective intra-arterial infusion of nimodipine may be an option in selected patients with symptomatic vasospasm refractory to conventional treatment after careful consideration of benefits and procedure-related risks.

U2 - 10.1186/s40064-016-3495-4

DO - 10.1186/s40064-016-3495-4

M3 - SCORING: Journal article

C2 - 27812447

VL - 5

SP - 1807

JO - SPRINGERPLUS

JF - SPRINGERPLUS

SN - 2193-1801

IS - 1

ER -