Childhood trauma and psychosis - what is the evidence?
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Childhood trauma and psychosis - what is the evidence? / Schäfer, Ingo; Fisher, Helen L.
In: DIALOGUES CLIN NEURO, Vol. 13, No. 3, 3, 2011, p. 360-365.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Childhood trauma and psychosis - what is the evidence?
AU - Schäfer, Ingo
AU - Fisher, Helen L
PY - 2011
Y1 - 2011
N2 - In the last decade, a substantial number of population-based studies have suggested that childhood trauma is a risk factor for psychosis. In several studies, the effects held after adjusting for a wide range of potentially confounding variables, including genetic liability for psychosis. Less is known about the mechanisms underlying the association between childhood trauma and psychosis. Possible pathways include relationships between negative perceptions of the self, negative affect, and psychotic symptoms, as well as biological mechanisms such as dysregulated cortisol and increased sensitivity to stress. Psychotic patients with a history of childhood trauma tend to present with a variety of additional problems, including post-traumatic stress disorder, greater substance abuse, higher levels of depression and anxiety, and more frequent suicide attempts. Initial studies suggest that trauma-specific treatments are as beneficial for these patients as for other diagnostic groups.
AB - In the last decade, a substantial number of population-based studies have suggested that childhood trauma is a risk factor for psychosis. In several studies, the effects held after adjusting for a wide range of potentially confounding variables, including genetic liability for psychosis. Less is known about the mechanisms underlying the association between childhood trauma and psychosis. Possible pathways include relationships between negative perceptions of the self, negative affect, and psychotic symptoms, as well as biological mechanisms such as dysregulated cortisol and increased sensitivity to stress. Psychotic patients with a history of childhood trauma tend to present with a variety of additional problems, including post-traumatic stress disorder, greater substance abuse, higher levels of depression and anxiety, and more frequent suicide attempts. Initial studies suggest that trauma-specific treatments are as beneficial for these patients as for other diagnostic groups.
KW - Humans
KW - Risk Factors
KW - Child
KW - Psychotic Disorders/epidemiology
KW - Community Health Planning
KW - Stress Disorders, Post-Traumatic/epidemiology
KW - Humans
KW - Risk Factors
KW - Child
KW - Psychotic Disorders/epidemiology
KW - Community Health Planning
KW - Stress Disorders, Post-Traumatic/epidemiology
M3 - SCORING: Journal article
VL - 13
SP - 360
EP - 365
JO - DIALOGUES CLIN NEURO
JF - DIALOGUES CLIN NEURO
SN - 1294-8322
IS - 3
M1 - 3
ER -