Central serotonin transporter levels are associated with stress hormone response and anxiety.

  • Matthias Reimold
  • Astrid Knobel
  • Michael A Rapp
  • Anil Batra
  • Klaus Wiedemann
  • Andreas Ströhle
  • Anke Zimmer
  • Peter Schönknecht
  • Michael N Smolka
  • Daniel R Weinberger
  • David Goldman
  • Hans-Jürgen Machulla
  • Roland Bares
  • Andreas Heinz

Abstract

Negative mood states are characterized by both stress hormone dysregulation and serotonergic dysfunction, reflected by altered thalamic serotonin transporter (5-HTT) levels. However, so far, no study examined the individual association between cortisol response and cerebral in vivo 5-HTT levels in patients suffering from negative mood states.

Bibliographical data

Original languageGerman
Article number2-3
ISSN0033-3158
Publication statusPublished - 2011
pubmed 20585760