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Catheter ablation of atrial fibrillation in the young: insights from the German Ablation Registry

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Catheter ablation of atrial fibrillation in the young: insights from the German Ablation Registry. / Chun, K R Julian; Schmidt, Boris; Kuck, Karl-Heinz; Andresen, Dietrich; Willems, Stefan; Spitzer, Stefan G; Hoffmann, Ellen; Schumacher, Burghard; Eckardt, Lars; Seidl, Karlheinz; Jünger, Claus; Horack, Martin; Brachmann, Johannes; Senges, Jochen.

In: CLIN RES CARDIOL, Vol. 102, No. 6, 06.2013, p. 459-468.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Chun, KRJ, Schmidt, B, Kuck, K-H, Andresen, D, Willems, S, Spitzer, SG, Hoffmann, E, Schumacher, B, Eckardt, L, Seidl, K, Jünger, C, Horack, M, Brachmann, J & Senges, J 2013, 'Catheter ablation of atrial fibrillation in the young: insights from the German Ablation Registry', CLIN RES CARDIOL, vol. 102, no. 6, pp. 459-468. https://doi.org/10.1007/s00392-013-0553-6

APA

Chun, K. R. J., Schmidt, B., Kuck, K-H., Andresen, D., Willems, S., Spitzer, S. G., Hoffmann, E., Schumacher, B., Eckardt, L., Seidl, K., Jünger, C., Horack, M., Brachmann, J., & Senges, J. (2013). Catheter ablation of atrial fibrillation in the young: insights from the German Ablation Registry. CLIN RES CARDIOL, 102(6), 459-468. https://doi.org/10.1007/s00392-013-0553-6

Vancouver

Chun KRJ, Schmidt B, Kuck K-H, Andresen D, Willems S, Spitzer SG et al. Catheter ablation of atrial fibrillation in the young: insights from the German Ablation Registry. CLIN RES CARDIOL. 2013 Jun;102(6):459-468. https://doi.org/10.1007/s00392-013-0553-6

Bibtex

@article{dc7dc93ceb27453eb2766e88361c8521,
title = "Catheter ablation of atrial fibrillation in the young: insights from the German Ablation Registry",
abstract = "INTRODUCTION: Catheter ablation of paroxysmal atrial fibrillation (PAF) has been suggested as first-line treatment for selected patients (pts). However, patient characteristics, procedural data, and complication rate in the group of young patients remain undetermined.METHODS: The German Ablation Registry has been designed as a multi-center prospective registry. AF ablation data were collected from 51 German centers between March 2007 to September 2012 and 2 groups were defined (group A: ≤45 years, group B: >45 years). Data were analyzed according to patient characteristics, procedural data, and complications. To calculate differences between both groups CHI2 or Mann-Whitney-Wilcoxon tests was utilized.RESULTS: A total of 7243 patients undergoing AF ablation were included (group A: 593, 8.2 %; group B: 6650, 91.8 %). Male gender and PAF were significantly more often present in group A. Patient characteristic revealed decreased co-morbidities in the young. In both groups circumferential pulmonary vein isolation represented the procedural cornerstone, whereas substrate modification was significantly more often performed in group B. Procedure-, and fluoroscopy-time was similar but there was a shorter hospital stay and a favorable complication profile in the young. After 12 months AF recurrence and use of antiarrhythmic drugs were less common in group A.CONCLUSION: The young AF ablation patient has typically paroxysmal AF and less comorbidities. In this group, catheter ablation of AF is associated with a lower major complication rate, shorter hospitalization, and a favorable clinical outcome.",
keywords = "Adult, Age Factors, Aged, Atrial Fibrillation/surgery, Catheter Ablation/methods, Female, Fluoroscopy, Follow-Up Studies, Germany, Hospitalization/statistics & numerical data, Humans, Length of Stay, Male, Middle Aged, Prospective Studies, Pulmonary Veins/surgery, Recurrence, Registries, Sex Factors, Statistics, Nonparametric, Time Factors, Treatment Outcome",
author = "Chun, {K R Julian} and Boris Schmidt and Karl-Heinz Kuck and Dietrich Andresen and Stefan Willems and Spitzer, {Stefan G} and Ellen Hoffmann and Burghard Schumacher and Lars Eckardt and Karlheinz Seidl and Claus J{\"u}nger and Martin Horack and Johannes Brachmann and Jochen Senges",
year = "2013",
month = jun,
doi = "10.1007/s00392-013-0553-6",
language = "English",
volume = "102",
pages = "459--468",
journal = "CLIN RES CARDIOL",
issn = "1861-0684",
publisher = "D. Steinkopff-Verlag",
number = "6",

}

RIS

TY - JOUR

T1 - Catheter ablation of atrial fibrillation in the young: insights from the German Ablation Registry

AU - Chun, K R Julian

AU - Schmidt, Boris

AU - Kuck, Karl-Heinz

AU - Andresen, Dietrich

AU - Willems, Stefan

AU - Spitzer, Stefan G

AU - Hoffmann, Ellen

AU - Schumacher, Burghard

AU - Eckardt, Lars

AU - Seidl, Karlheinz

AU - Jünger, Claus

AU - Horack, Martin

AU - Brachmann, Johannes

AU - Senges, Jochen

PY - 2013/6

Y1 - 2013/6

N2 - INTRODUCTION: Catheter ablation of paroxysmal atrial fibrillation (PAF) has been suggested as first-line treatment for selected patients (pts). However, patient characteristics, procedural data, and complication rate in the group of young patients remain undetermined.METHODS: The German Ablation Registry has been designed as a multi-center prospective registry. AF ablation data were collected from 51 German centers between March 2007 to September 2012 and 2 groups were defined (group A: ≤45 years, group B: >45 years). Data were analyzed according to patient characteristics, procedural data, and complications. To calculate differences between both groups CHI2 or Mann-Whitney-Wilcoxon tests was utilized.RESULTS: A total of 7243 patients undergoing AF ablation were included (group A: 593, 8.2 %; group B: 6650, 91.8 %). Male gender and PAF were significantly more often present in group A. Patient characteristic revealed decreased co-morbidities in the young. In both groups circumferential pulmonary vein isolation represented the procedural cornerstone, whereas substrate modification was significantly more often performed in group B. Procedure-, and fluoroscopy-time was similar but there was a shorter hospital stay and a favorable complication profile in the young. After 12 months AF recurrence and use of antiarrhythmic drugs were less common in group A.CONCLUSION: The young AF ablation patient has typically paroxysmal AF and less comorbidities. In this group, catheter ablation of AF is associated with a lower major complication rate, shorter hospitalization, and a favorable clinical outcome.

AB - INTRODUCTION: Catheter ablation of paroxysmal atrial fibrillation (PAF) has been suggested as first-line treatment for selected patients (pts). However, patient characteristics, procedural data, and complication rate in the group of young patients remain undetermined.METHODS: The German Ablation Registry has been designed as a multi-center prospective registry. AF ablation data were collected from 51 German centers between March 2007 to September 2012 and 2 groups were defined (group A: ≤45 years, group B: >45 years). Data were analyzed according to patient characteristics, procedural data, and complications. To calculate differences between both groups CHI2 or Mann-Whitney-Wilcoxon tests was utilized.RESULTS: A total of 7243 patients undergoing AF ablation were included (group A: 593, 8.2 %; group B: 6650, 91.8 %). Male gender and PAF were significantly more often present in group A. Patient characteristic revealed decreased co-morbidities in the young. In both groups circumferential pulmonary vein isolation represented the procedural cornerstone, whereas substrate modification was significantly more often performed in group B. Procedure-, and fluoroscopy-time was similar but there was a shorter hospital stay and a favorable complication profile in the young. After 12 months AF recurrence and use of antiarrhythmic drugs were less common in group A.CONCLUSION: The young AF ablation patient has typically paroxysmal AF and less comorbidities. In this group, catheter ablation of AF is associated with a lower major complication rate, shorter hospitalization, and a favorable clinical outcome.

KW - Adult

KW - Age Factors

KW - Aged

KW - Atrial Fibrillation/surgery

KW - Catheter Ablation/methods

KW - Female

KW - Fluoroscopy

KW - Follow-Up Studies

KW - Germany

KW - Hospitalization/statistics & numerical data

KW - Humans

KW - Length of Stay

KW - Male

KW - Middle Aged

KW - Prospective Studies

KW - Pulmonary Veins/surgery

KW - Recurrence

KW - Registries

KW - Sex Factors

KW - Statistics, Nonparametric

KW - Time Factors

KW - Treatment Outcome

U2 - 10.1007/s00392-013-0553-6

DO - 10.1007/s00392-013-0553-6

M3 - SCORING: Journal article

C2 - 23503755

VL - 102

SP - 459

EP - 468

JO - CLIN RES CARDIOL

JF - CLIN RES CARDIOL

SN - 1861-0684

IS - 6

ER -